SavedAdd your journal

Journals / Spor Hekimliği Dergisi / 2019 / Cilt: 54 - Sayı: 1

The Effects of Swimming on Blood Nitric Oxide and Haematological Parameters

Yüzmenin Kan Nitrik Oksit ve Hematolojik Parametreler Üzerine Etkisi

Ali Rıza ŞİŞMAN
Faruk TURGAY
M. Armağan ONGUN
M. Akın ONGUN
Muzaffer ÇOLAKOĞLU
Pages
24–32
Publication Date
2022-10-19
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

NOx was greater in RTP compared with DTP (p

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Background: Nitric oxide (NO) is a gas with atherosclerosis-inhibiting effect.
📊
Key Findings & Data:Ten trained male swimmers (11.1±0.6years old) joined the study.
💡
Conclusion & Impact:NOx was greater in RTP compared with DTP (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Background: Nitric oxide (NO) is a gas with atherosclerosis-inhibiting effect. NO isalso involved in the structure and function of erythrocytes (RBCs). Blood NO levels andhaematological parameters (HPs) and the relationship between these parameters inswimmers over one-year training season have not yet been evaluated.Material and Methods: The effects of training (TP), detraining (DTP), and retrainingperiod (RTP) on blood NOx (as total nitrite) levels and the relationships between NOand HPs in child swimmers were investigated. Ten trained male swimmers (11.1±0.6years old) joined the study. With intervals of two months; blood biochemistry, physicaland physiological measurements were performed after TP, DTP, and RTP. As anendurance criterion, critical speed (CS) was measured. Venous blood was obtainedafter 12 hours of fasting, serum iron, ferritin, total iron binding capacity, NOx (by Cd++mediated 'Griess' assay) levels were measured, and haemograms were assessed.Results: NOx levels during TP were below the baseline levels (19.3%) and increasedto the baseline during DTP. NOx was greater in RTP compared with DTP (p

Özet

Giriş: Nitrik oksit (NO), aterosklerozu engelleyici etkilere sahip bir gazdır. NO, aynı zamanda eritrositlerin (KKH) yapısı ve fonksiyonunda da rol alır. Bir yıllık yüzme sezonunun çocuklarda kan NO düzeyleri ve hematolojik parametreler (HPs) ile buparametreler arasındaki ilişkiler üzerine etkileri bilinmemektedir. Amaç: Bu çalışmada sekiz aylık bir antrenman periyodu (AP), deantrenman periyodu (DAP) ve reantrenman (RAP) periyotlarının kan NOx (total nitrit olarak) ve HPs’ler üzerine etkileri ve bu parametreler arasındaki ilişkiler araştırıldı. Gereç ve Yöntemler: Çalışmaya yaş ortalaması (11.1±0.6 yıl) olan 10 sağlıklı antrene yüzücü erkek çocuk katıldı. İki ay aralıklarla; AP, DAP ve RAP sonrası kan biyokimyası, fiziksel ve fizyolojik ölçümler yapıldı. Dayanıklılık kriteri olarak; kritik hız (KH) ölçüldü. Oniki saatlik açlık sonrası alınan venöz kan örneklerinden hemogram; serumda demir, ferritin, total demir bağlama kapasitesi ve NOx (Cd++ aracılı ‘Griess’ yöntemi ile) düzeyleri ölçüldü. Bulgular: NOx değeri, AP’de bazal değerlerinin altında (19.3%) iken DAP’de artarak bazal değerlerine döndü. RAP’de anlamlı olarak arttı (p

🔖

Cite This Article

ŞİŞMAN, A. R., TURGAY, F., ONGUN, M. A., ONGUN, M. A., ÇOLAKOĞLU, M. (2022). The Effects of Swimming on Blood Nitric Oxide and Haematological Parameters. Spor Hekimliği Dergisi, Cilt: 54 - Sayı: 1, 24–32. https://ajindex.com/articles/593268

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (14)

  1. Kingwell BA. Nitric oxide-mediated metabolic regulation during exercise: effects of training in health and cardiovascular disease (Review). FASEB J. 2000;14(12):1685-96
  2. Forstermann U. Nitric oxide and oxidative stress in vascular disease (Review). Pflugers Arch. 2010;459(6): 923-39
  3. Quyyumi AA, Dakak N, Andrews NP, et al. Nitric oxide activity in the human coronary circulation. Impact of risk factors for coronary atherosclerosis. J Clin Invest. 1995;95(4):1747-55
  4. Crawford JH, Chacko BK, Kevil CG, et al. The red blood cell and vascular function in health and disease (Review). Antioxid Redox Signal. 2004;6(6):992-9
  5. Gladwin MT, Crawford JH, Patel RP. The biochemistry of nitric oxide, nitrite, and hemoglobin: role in blood flow regulation (Review). Free Radic Biol Med. 2004; 36(6):707-17
  6. Schaer DJ, Buehler PW, Alayash AI, et al. Hemolysis and free hemoglobin revisited: exploring hemoglobin and hemin scavengers as a novel class of therapeutic proteins. Blood. 2013;121(8):1276-84
  7. Dufour SP, Patel RP, Brandon A, et al. Erythrocytedependent regulation of human skeletal muscle blood flow: role of varied oxyhemoglobin and exercise on nitrite, S-nitrosohemoglobin, and ATP. Am J Physiol Heart Circ Physiol. 2010;299(6):H1936-46
  8. Han TH, Qamirani E, Nelson AG, et al. Regulation of nitric oxide consumption by hypoxic red blood cells. Proc Natl Acad Sci U S A. 2003;100(21):12504-9
  9. Suhr F, Porten S, Hertrich T, et al. Intensive exercise induces changes of endothelial nitric oxide synthase pattern in human erythrocytes. Nitric Oxide. 2009;20(2): 95-103
  10. Sentürk UK, Gündüz F, Kuru O, et al. Exercise-induced oxidative stress affects erythrocytes in sedentary rats but not exercise-trained rats. J Appl Physiol (1985). 2001;91(5):1999-2004
  11. Qian ZM, Xiao DS, Ke Y, et al. Increased nitric oxide is one of the causes of changes of iron metabolism in strenuously exercised rats. Am J Physiol Regul Integr Comp Physiol. 2001;280(3):R739-43
  12. Lauer T, Preik M, Rassaf T, et al. Plasma nitrite rather than nitrate reflects regional endothelial nitric oxide synthase activity but lacks intrinsic vasodilator action. Proc Natl Acad Sci U S A. 2001;98(22):12814-9
  13. Zhang QJ, McMillin SL, Tanner JM, et al. Endothelial nitric oxide synthase phosphorylation in treadmill-running mice: role of vascular signalling kinases. J Physiol. 2009;587(Pt 15):3911-20
  14. Kerkweg U, Schmitz D, de Groot H. Screening for the formation of reactive oxygen species and