AI Summary & Key Takeaways
AI InsightHowever, PRP was superior to PrT in terms of painlevel during exercise, range of motion, crepitus, total number of medications, VAS andTLS (p=0.004, p=0.038, p˂0.001, p=0.003, p=0.001 and p=0.026 respectively).Conclusions: PRP and PrT therapies applied with exercise were shown to be effectivein CMP treatment; however PRP therapy seems to be more effective than PrT.
📌 3 Key Takeaways
Abstract
Objective: Chondromalacia patella (CMP) is a frequently seen musculoskeletaldisorder. Platelet-rich plasma (PRP) is considerably useful in sports injuries.Prolotherapy (PrT) is a regenerative injection technique used in chronicmusculoskeletal disorders. The aim of this study is to compare PRP and PrT therapiesin CMP treatment.Materials and Methods: Seventy five patients with CMP symptoms refractory to threemonths of conservative treatment methods were included in this study. The patientswere divided into PRP (n=38) and PrT (n=37) groups. A questionnaire has beenapplied, VAS scores, Tegner and Lysholm knee scores (TLS) were obtained. Theywere repeated three, six weeks after the beginning of treatment, and 12 monthsfollowing the treatment. A standard 12-week exercise program was prescribed to all ofthe patients.Results: Pain and knee functions improved significantly after a minimum one year offollow-up in both groups (p˂0.05). However, PRP was superior to PrT in terms of painlevel during exercise, range of motion, crepitus, total number of medications, VAS andTLS (p=0.004, p=0.038, p˂0.001, p=0.003, p=0.001 and p=0.026 respectively).Conclusions: PRP and PrT therapies applied with exercise were shown to be effectivein CMP treatment; however PRP therapy seems to be more effective than PrT.
Özet
Amaç: Kondromalazi patella (CMP), sık görülen bir kas-iskelet sistemi hastalığıdır. Trombositten zengin plazmanın (PRP), spor yaralanmalarında önemli ölçüde faydalı olduğu bilinmektedir. Proloterapi (PrT) ise, kronik kas-iskelet sistemi hastalıkları için kullanılan rejeneratif bir enjeksiyon tekniğidir. Bu çalışmanın amacı, CMP tedavisinde PRP ve PrT tedavilerinin etkinliğini karşılaştırmaktır. Gereç ve Yöntemler: Üç ay süren konservatif tedaviye dirençli yetmiş beş CMP hastası çalışmaya alındı. Hastalar randomize olarak PRP veya PrT grupları olarak iki gruba ayrıldı. Hasta sorgulama anketi, VAS, Tegner ve Lysholm diz skorları (TLS) uygulandı. Bunlar tedavinin başlangıcından üç, altı hafta sonra ve tedaviden 12 ay sonra tekrarlandı. Tüm hastalara 12 haftalık standart egzersiz programı verildi. Bulgular: Her iki grubun da ağrı ve diz fonksiyonları bir yıllık izlemden sonra belirgin olarak düzeldi (p