Journals / Southern Clinics of Istanbul Eurasia / 2018 / Cilt: 29 - Sayı: 3

Surgical Treatment of Pulmonary Metastasectomy: Analysis of 92 Cases

Pulmoner Metastazektomilerde Cerrahi Tedavi: 92 Olgu Analizi

Pages
147–150
Publication Date
2022-10-19
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

When the primary disease is under control and there is no other distant metastasis, metastasectomy with complete surgical resection can provide an extended period ofDFS, particularly for patients with epithelial or sarcomatous tumors.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: The lungs are the second most common site of metastasis, and for selectedpatients, pulmonary metastasectomy can be a curative option.
📊
Key Findings & Data:In well-selected cases,minimally invasive approaches can increase quality of life and offer equivalent oncologicaloutcomes.Methods: Patients diagnosed with pulmonary metastasis who underwent a metastasectomy in a single hospital between January 2012 and December 2017 were evaluated retrospectively.
💡
Conclusion & Impact:When the primary disease is under control and there is no other distant metastasis, metastasectomy with complete surgical resection can provide an extended period ofDFS, particularly for patients with epithelial or sarcomatous tumors.
🔬Design:Research Article
📍Scope:2012 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: The lungs are the second most common site of metastasis, and for selectedpatients, pulmonary metastasectomy can be a curative option. The surgical goal is completeresection with minimal parenchymal loss in order to prolong life. In well-selected cases,minimally invasive approaches can increase quality of life and offer equivalent oncologicaloutcomes.Methods: Patients diagnosed with pulmonary metastasis who underwent a metastasectomy in a single hospital between January 2012 and December 2017 were evaluated retrospectively. A total of 92 patients (55 male and 37 female) underwent thoracotomy orthoracoscopy procedures with the goal of complete resection.Results: Among the patients included in the study, 8 were symptomatic: cough was reported in 3, chest pain (pneumothorax) was experienced in 3, and hemoptysis occurred in2 cases. The longest disease-free survival (DFS) period was seen in cases of epithelial tumor(40.1 months) and sarcoma (28.2 months); the shortest survival was seen in those with germcell tumor (8.3 months) and melanoma (8.1 months).Conclusion: Patients with pulmonary metastasis require a multidisciplinary approach fortreatment. When the primary disease is under control and there is no other distant metastasis, metastasectomy with complete surgical resection can provide an extended period ofDFS, particularly for patients with epithelial or sarcomatous tumors.

Özet

Amaç: Akciğer, tüm vücut kanserleri için ikinci en sık metastaz organı olup seçilmiş hastalarda pulmoner metastazektomi küratif seçenektir. Operatif yaklaşımda temel amaç en az parankim kaybı ile komplet rezeksiyon yapmak ve doğru hasta seçimi ile sağ kalım süresini uzatmaktır. İyi seçilmiş hastalarda minimal invaziv girişimler hastanın ameliyat sonrası yaşam kalitesini, eşit onkolojik sonuçlarla artırabilmektedir. Gereç ve Yöntem: Ocak 2012–Aralık 2017 tarihleri arasında pulmoner metastaz tanısı ile kliniğimizde metastazektomi yapılan hastalar incelendi. Klinik değerlendirme sonrasında pulmoner rezeksiyona uygun olan 92 hasta (55 erkek ve 37 kadın) operasyona hazırlandı. Torakotomi ve torakoskopi prosedürleri ile cerrahi uygulanan hastalarda komplet rezeksiyon amaçlandı. Bulgular: Çalışmamıza alınan hastalar başvuru anında semptomlar açısından değerlendirildiğinde, 8 olgu semptomlu olarak saptandı ve bunlardan 3’ünde öksürük, 3’ünde göğüs ağrısı (pnömotoraks nedeni ile) mevcuttu. Histopatolojik tip ile hastalıksız yaşam süresi değerlendirmesinde ise en yüksek yaşam süresi epiteltal tümörlerde (40.1 ay) ve sarkomlarda (28.2 ay) saptanırken, germ hücreli tümörlerde (8.3 ay) ve melanomlarda (8.1) ise en düşük olarak izlendi. Sonuç: Multidisipliner bir tedavi yaklaşımı gerektiren pulmoner metastazlı hastaların; primer hastalığı kontrol altında, uzak metastazı olmayıp ve komplet cerrahi rezeksiyon uygulanabiliyor ise özellikle epitelyal tip ve sarkom tipi tümörlerde metastazektominin hastalıksız yaşam süresine ve ortalama sağkalıma ciddi katkısı olduğu kanaatindeyiz.

🔖

Cite This Article

ÖZDEMİR, A., ÖZER, K. B., ÖZLÜ, F. T., CESUR, E. E., DEMİRHAN, R. (2022). Surgical Treatment of Pulmonary Metastasectomy: Analysis of 92 Cases. Southern Clinics of Istanbul Eurasia, Cilt: 29 - Sayı: 3, 147–150. https://ajindex.com/articles/592916

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (12)

  1. Hornbeck K, Ravn J, Steinbruchel DA. Current status of pulmonary metastasectomy. European Journal of Cardio-Thoracic Surgery 2011;39:955–62
  2. Abecasis N, Cortez F, Bettencourt A, Costa CS, Orvalho F, de Almeida JM. Surgical treatment of lung metastases: prognostic factors for long-term survival. J Surg Oncol 1999;72:193–8
  3. Putnam JB. Secondary tumors of the lung. In: Shields TW, Locicero J, Ponn RB, editors. General thoracic surgery. 5th ed. Philadelphia: Lippincott Williams & Wilkins; 2000. p. 1555–76
  4. Şengül AT, Başoğlu A, Büyükkarabacak AB, Yetim TD, Kutlu T. Assessment of metastasectomy and prognostic factors in the treatment of metastatic lung tumors [Article in Turkish]. Türk Göğüs Kalp Damar Cer Derg 2009;17:87–91
  5. Robert JH, Ambrogi V, Mermillod B, Dahabreh D, Goldstraw P. Factors influencing long-term survival after lung metastasectomy. Ann Thorac Surg 1997;63:777–84
  6. Pastorino U, Buyse M, Friedel G, Ginsberg RJ, Girard P, Goldstraw P, et al; International Registry of Lung Metastases. Long-term results of lung metastasectomy: prognostic analyses based on 5206 cases. J Thorac Cardiovasc Surg 1997;113:37–49
  7. Petrella F, Diotti C, Rimessi A, Spaggiari L. Pulmonary Metastasectomy: an overview. J Thorac Dis 2017;9:S1291–8
  8. Lucas JD, O’Doherty MJ, Wong JC, Bingham JB, McKee PH, Fletcher CD, et al. Evaluation of fluorodeoxyglucose positron emission tomography in the management of soft-tissue sarcomas. J Bone Joint Surg Br 1998;80:441–7
  9. Monteiro A, Arce N, Bernardo J, Eugénio L, Antunes MJ. Surgical resection of lung metastases from epithelial tumors. Ann Thorac Surg 2004;77:431–7
  10. Turna A, İşcan M. Lymphdenectomy in Patients Undergoing Pulmonary Metastasectomy [Article in Turkish]. Turkiye Klinikleri J Thor Surg-Special Topics 2017;8:411–4
  11. Marina NM, Pratt CB, Rao BN, Shema SJ, Meyer WH. Improved prognosis of children with osteosarcoma metastatic to the lung(s) at the time of diagnosis. Cancer 1992;70:2722–7
  12. Evman S, Demirhan R, Çardak E, Özer KB. Who Actually Profits From Pulmonary Metastasectomy Operation? Retrospective Analysis of 12 Years. Eurasian J Pulmonol 2014;16:164–8.