Is the Surgical Approach Very Important to Treatment for Phyllodes Tumors?

Objective & Hypothesis:Objective: The aim of the present study was to evaluate the treatment modalities andrecurrence status of patients diagnosed with phyllodes tumor in light of a literature search.Methods: All female patients who received treatment for phyllodes tumor between January2015 and January 2017 were included in our study.

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Key Findings & Data:Histopathological results, type of surgery, application of chemoradiotherapy, tumor size, recurrence rate, and demographic data were analyzed.Results: Twenty-five cases were evaluated.

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Conclusion & Impact:There is noconsensus for the application of chemo- and radiotherapy.

🔬Design:Research Article

📍Scope:2017 Verileri

⚙️Variables:Domain Parameters

Abstract

Objective: The aim of the present study was to evaluate the treatment modalities andrecurrence status of patients diagnosed with phyllodes tumor in light of a literature search.Methods: All female patients who received treatment for phyllodes tumor between January2015 and January 2017 were included in our study. All data were collected through retrospective analysis. Histopathological results, type of surgery, application of chemoradiotherapy, tumor size, recurrence rate, and demographic data were analyzed.Results: Twenty-five cases were evaluated. Of the 25 cases, 8 were diagnosed as malignant.The rest were 3 borderline and 14 benign and fibroadenomas. Three of 8 malignancies weretreated with mastectomy, and the other 5 were treated with wide local excision. Recurrenceoccurred in two cases; one of them received chemotherapy, and the other had chemoradiotherapy. All 17 remaining patients underwent wide local excision. A single case was treatedwith mastectomy due to large tumor size.Conclusion: There is still an ongoing debate for the treatment of phyllodes tumors. Negative margins for malignant cases play a major role for successful treatment. There is noconsensus for the application of chemo- and radiotherapy.

Özet

Amaç: Filoides tümörü tanısı alan hastaların kliniğimizdeki tedavi ve nüks durumunu literatür eşliğinde irdelemek. Gereç ve Yöntem: Ocak 2015 ile ocak 2017 tarihleri arasında fibroepitelyal tümör tanısı ile ameliyat edilen kadın hastalar dahil edildi. Veriler hasta dosyası incelenerek geriye dönük toplandı. Hastalar patoloji sonuçlarına göre yapılan ameliyat, kemoterapi ve radypterapi alıp almamaları, kitlenin büyüklüğü, nüks ve demografik özelliklerine göre değerlendirildi. Bulgular: Toplam 25 hasta değerlendirildi. Bunlardan sekizi malign filoides tümör, üçü Borderline filoides tümör, 14’ü benign filoides tümör ve fibroadenomatoz lezyon idi. Sekiz malign filoides tümörlü hastanın üçüne mastektomi beşine geniş lokal eksizyon (GLE) yapıldı. İki hastada nüks gelişti. Bunlardan birisine kemoterapi (KT), diğerine KT ve radyoterapi (RT) uygulanmıştı. Diğer 17 hastadan biri hariç (kitle memeyi tamamen kapladığı için mastektomi yapıldı) hepsine GLE uygulandı. Sonuç: Malign filoides tümör tedavisi için çeşitli görüşler bulunmaktadır. Ancak cerrahi sınır negatifliği ön plana çıkmaktadır. RT ve KT eklenip eklenmemesi halen tartışmalıdır.

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Cite This Article

KAYA, S., ÇETİN, K., KÜNDEŞ, M. F., KÜÇÜK, H. F. (2022). Is the Surgical Approach Very Important to Treatment for Phyllodes Tumors?. Southern Clinics of Istanbul Eurasia, Cilt: 30 - Sayı: 2, 130–134. https://ajindex.com/articles/592894

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