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Journals / Retina-Vitreus / 2019 / Cilt: 28 - Sayı: 3

Evaluation of Lamina Cribrosa Layer in Multiple Sclerosis

Multiple Sklerozda Lamina Kribroza Tabakasının Araştırılması

Özkan KOCAMIŞ
Burç Esra ŞAHİN
Pages
296–301
Publication Date
2022-10-17
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

LCT was statistically significantly lower in the MS group than the control group (p

📌 3 Key Takeaways

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Objective & Hypothesis:Purpose: We aimed to measure lamina cribrosa thickness (LCT), lamina cribrosa depth (LCD) and retinal nerve fiber layer (RNFL) thickness in multiple sclerosis (MS) patients and compare the results with eyes of healthy subjects.Materials and Methods: The eyes of multiple sclerosis patients were compared with the eyes of a healthy control group.
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Key Findings & Data:Correlation analysis was conducted between the Expanded Disability Status Scale (EDSS) score and disease duration of the MS patients and the LCT, LCD, and RNFL thicknesses.Results: Mean LCT values were 171.86±62.81 μm in the MS group and 230.1±66.84 μm in the control group.
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Conclusion & Impact:LCT was statistically significantly lower in the MS group than the control group (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Purpose: We aimed to measure lamina cribrosa thickness (LCT), lamina cribrosa depth (LCD) and retinal nerve fiber layer (RNFL) thickness in multiple sclerosis (MS) patients and compare the results with eyes of healthy subjects.Materials and Methods: The eyes of multiple sclerosis patients were compared with the eyes of a healthy control group. A full ophthalmologic examination was conducted for both groups. Optic coherence tomography (OCT) was used to measure LCT, LCD, and RNFL thickness values. Correlation analysis was conducted between the Expanded Disability Status Scale (EDSS) score and disease duration of the MS patients and the LCT, LCD, and RNFL thicknesses.Results: Mean LCT values were 171.86±62.81 μm in the MS group and 230.1±66.84 μm in the control group. LCT was statistically significantly lower in the MS group than the control group (p

Özet

Amaç: Multipl skleroz (MS) hastalarında lamina cribrosa kalınlığı (LKK), lamina cribrosa derinliği (LKD) ve retina sinir lifi tabakası (RSLT) kalınlığını ölçmeyi ve sağlıklı gözlerin sonuçları ile karşılaştırmayı amaçladık. Gereç ve Yöntemler: Multipl skleroz hastalarının gözleri sağlıklı kontrol grubunun gözleri ile karşılaştırıldı. Her iki grup için tam oftalmolojik muayene yapıldı. LKK, LKD ve RSLT kalınlık değerlerini ölçmek için optik koherens tomografi (OKT) kullanıldı. MS hastalarının Genişletilmiş Engellilik Durum Ölçeği (GEDÖ) skoru ve hastalık süresi ile LKK, LKD ve RSLT kalınlıkları arasında korelasyon analizi yapıldı. Bulgular: Ortalama LKK değerleri MS grubunda 171.86 ± 62.81 μm, kontrol grubunda 230.1 ± 66.84 μm idi. LKK MS grubunda kontrol grubundan istatistiksel olarak anlamlı derecede düşüktü (p

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Cite This Article

KOCAMIŞ, Ö., ŞAHİN, B. E. (2022). Evaluation of Lamina Cribrosa Layer in Multiple Sclerosis. Retina-Vitreus, Cilt: 28 - Sayı: 3, 296–301. https://ajindex.com/articles/589114

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