Journals / Retina-Vitreus / 2019 / Cilt: 28 - Sayı: 4

Analysis of Macular Retinal Nerve Fiber Layer, Ganglion Cell Layer and Ganglion Cell Complex in Pseudoexfoliation Syndrome

Pages
192–199
Publication Date
2022-10-17
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

There was no signifi cant difference between the two groups in the inner plexiform layer (p

📌 3 Key Takeaways

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Objective & Hypothesis:Purpose: Evaluation of macular retinal nerve fi ber layer (RNFL), ganglion cell layer (GCL), and ganglion cell complex (GCC) in pseudoexfoliation syndrome (PES) by spectral domain-optical coherence tomography (SD-OCT).
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Key Findings & Data:Material and methods: One eye of 30 patients with PES and one eye of 30 healthy subjects were included in the study.
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Conclusion & Impact:There was no signifi cant difference between the two groups in the inner plexiform layer (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Purpose: Evaluation of macular retinal nerve fi ber layer (RNFL), ganglion cell layer (GCL), and ganglion cell complex (GCC) in pseudoexfoliation syndrome (PES) by spectral domain-optical coherence tomography (SD-OCT). Material and methods: One eye of 30 patients with PES and one eye of 30 healthy subjects were included in the study. The participants' macular screening was performed in 9 quadrants by SD-OCT according to the early treatment diabetic retinopathy study (ETDRS). Retinal layers were automatically divided into segments using SD-OCT's own software and analyzed separately. Results: Statistically thinning was observed in the perifoveal nasal quadrant in RNFL (p = 0.035); in the perifoveal nasal (P = 0.041) and inferior quadrants (p = 0.034) in GCL and in the perifoveal nasal quadrant (p = 0.035) in GCC of the PES group when compared to the control group. There was no signifi cant difference between the two groups in the inner plexiform layer (p

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Cite This Article

MİRZA, E. (2022). Analysis of Macular Retinal Nerve Fiber Layer, Ganglion Cell Layer and Ganglion Cell Complex in Pseudoexfoliation Syndrome. Retina-Vitreus, Cilt: 28 - Sayı: 4, 192–199. https://ajindex.com/articles/589105

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References (14)

  1. Anastasopoulos E, Founti P, Topouzis F. Update on pseudoexfoliation syndrome pathogenesis and associations with intraocular pressure, glaucoma and systemic diseases. Curr Opin Ophthalmol. 2015;26:82-9
  2. Zenkel M, Schlötzer-Schrehardt U. The composition of exfoliation material and the cells involved in its production. J Glaucoma. 2014;23:S12–4
  3. Lindberg JG. Clinical investigations on depigmentation of the pupillary border and translucency of the iris in cases of senile cataract and in normal eyes in elderly persons. Acta Ophthalmol Suppl. 1989;190:1–96
  4. Ritch R, Schlotzer-Schrehardt U. Exfoliation syndrome. Surv Ophthalmol. 2001;45:265–315
  5. Streeten BW, Li ZY, Wallace RN, et al. Pseudoexfoliative fi brillopathy in visceral organs of a patient with pseudoexfoliation syndrome, Archives of Ophthalmology. 1992;110:1757–62
  6. Schlötzer-Schrehardt U, Küchle M, Naumann GOH. Electronmicroscopic identifi cation of pseudoexfoliation material in extrabulbar tissue. Arch Ophthalmol. 1991;109:565–70
  7. Detorakis ET, Achtaropoulos AK, Drakonaki EE, et al. Hemodynamic evaluation of the posterior ciliary circulation in exfoliation syndrome and exfoliation glaucoma. Graefes Arch Clin Exp Ophthalmol. 2007;245:516–21
  8. Dayanir V, Topaloglu A, Ozsunar Y, et al. Orbital blood fl ow parameters in unilateral pseudoexfoliation syndrome. Int Ophthalmol. 2009; 29:27–32
  9. Demircan S, Yılmaz U, Küçük E, et al. The Effect of Pseudoexfoliation Syndrome on the Retinal Nerve Fiber Layer and Choroid Thickness. Semin Ophthalmol. 2017;32:341-7
  10. Harju M, Vesti E. Blood fl ow of the optic nerve head and peripapillary retina in exfoliation syndrome with unilateral glaucoma or ocular hypertension. Graefes Arch Clin Exp Ophthalmol. 2001;239:271-7
  11. Ocakoglu O, Koyluoglu N, Kayiran A, et al. Microvascular blood fl ow of the optic nerve head and peripapillary retina in unilateral exfoliation syndrome. Acta Ophthalmol Scand. 2004;82:49-53
  12. Yuksel N, Karabas VL, Arslan A, et al. Ocular hemodynamics in pseudoexfoliation syndrome and pseudoexfoliation glaucoma. Ophthalmology. 2001;108:1043-9
  13. Garas A, Vargha P, Hollo G. Diagnostic accuracy of nerve fi bre layer, macular thickness and optic disc measurements made with the RTVue-100 optical coherence tomograph to detect glaucoma. Eye (Lond). 2011;25:57-65
  14. Medeiros FA, Zangwill LM, Bowd C, et al. Evaluation of retinal nerve fi ber layer, optic nerve head, and macular thickness measurements for glaucoma detection usi