Journals / Retina-Vitreus / 2019 / Cilt: 28 - Sayı: 1

Impending Central Retinal Vein Occlusion and Cilioretinal Artery Occlusion in a Pediatric Case with MTHFR A1298C Heterozygous Polymorphism and ANA Positivity

MTHFR A1298C Heterozigot Polimorfi zmli bir Pediatrik Olguda Santral Retinal Ven Oklüzyonu Tehdidi ve Silioretinal Arter Oklüzyonu

Pages
83–86
Publication Date
2022-10-17
DOI
—
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

A 13-year-old boy presented with impending central retinal venous occlusion followed by ciliary artery occlusion and vitreous hemorrhage.A detailed systemic investigation revealed ANA positivity and heterozygote polymorphism in MTHFR A1298C.Visual acuity immediatelyimproved after starting topical anti-glaucomatous treatment for impending central retinal venous occlusion and remained at 1.0 during the6-month follow-up .

📌 3 Key Takeaways

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Objective & Hypothesis:A 13-year-old boy presented with impending central retinal venous occlusion followed by ciliary artery occlusion and vitreous hemorrhage.A detailed systemic investigation revealed ANA positivity and heterozygote polymorphism in MTHFR A1298C.Visual acuity immediatelyimproved after starting topical anti-glaucomatous treatment for impending central retinal venous occlusion and remained at 1.0 during the6-month follow-up .
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Key Findings & Data:A 13-year-old boy presented with impending central retinal venous occlusion followed by ciliary artery occlusion and vitreous hemorrhage.A detailed systemic investigation revealed ANA positivity and heterozygote polymorphism in MTHFR A1298C.Visual acuity immediatelyimproved after starting topical anti-glaucomatous treatment for impending central retinal venous occlusion and remained at 1.0 during the6-month follow-up .
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Conclusion & Impact:A 13-year-old boy presented with impending central retinal venous occlusion followed by ciliary artery occlusion and vitreous hemorrhage.A detailed systemic investigation revealed ANA positivity and heterozygote polymorphism in MTHFR A1298C.Visual acuity immediatelyimproved after starting topical anti-glaucomatous treatment for impending central retinal venous occlusion and remained at 1.0 during the6-month follow-up .
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

A 13-year-old boy presented with impending central retinal venous occlusion followed by ciliary artery occlusion and vitreous hemorrhage.A detailed systemic investigation revealed ANA positivity and heterozygote polymorphism in MTHFR A1298C.Visual acuity immediatelyimproved after starting topical anti-glaucomatous treatment for impending central retinal venous occlusion and remained at 1.0 during the6-month follow-up .

Özet

Santral retinal ven oklüzyonu tehdidi ile başvuran 13 yaşında erkek hastada, takiben silier arter oklüzyonu ve vitre hemorajisi gelişti. Ayrıntılı bir sistemik araştırma sonucunda ANA pozitifl iği ve MTHFR A1298C heterozigot polimorfi zmi saptandı. Santral retinal ven oklüzyonu tehdidi için topikal anti-glokomatöz tedaviye başlandıktan hemen sonra görme keskinliğinin arttığı ve 6. ay kontrolünde 1.0 düzeyini koruduğu izlendi .

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Cite This Article

KAŞIKÇI, S. A., PARÇA, O., ZEYBEK, S., YÜKSEL, S., PEKEL, G., ÇETİN, E. N. (2022). Impending Central Retinal Vein Occlusion and Cilioretinal Artery Occlusion in a Pediatric Case with MTHFR A1298C Heterozygous Polymorphism and ANA Positivity. Retina-Vitreus, Cilt: 28 - Sayı: 1, 83–86. https://ajindex.com/articles/589101

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References (13)

  1. Fong ACO, Schatz H. Central retinal vein occlusion in young adults. Surv Ophthalmol 1993;37:393–417. Kácerik M, Mikulás AM, Lipková B. Combined occlusion of cen- tral retinal vein. Cesk Slov Oftalmol 2009;65(5):187-9.
  2. McLeod D, Ring CP. Cilio-retinal infarction after retinal vein oc- clusion. Br J Ophthalmol 1976;60:419–27.
  3. Zylbermann R, Rozenman Y, Ronen S. Functional occlusion of a cilioretinal artery. Am Ophthalmol 1981;13:1269–72.
  4. Glacet-Bernard A, Gaudric A, Touboul C et al. Occlusion of the central retinal vein with occlusion of a cilioretinal artery: apropos of 7 cases. J Fr Ophthalmol 1987;10:269–77.
  5. Schatz H, Fong AC, McDonald HR et al. Cilioretinal artery occlu- sion in young adults with central retinal vein occlusion. Ophthal- mology.1991;98:594–601.
  6. Brazitikos PD, Pournaras CJ, Othenin-Girard P et al. Pathogenetic mechanisms in combined cilioretinal artery and retinal vein occlu- sion: a reappraisal. Int Ophthalmol 1993;17:235–42.
  7. Keyser BJ, Duker JS, Brown GC et al. Combined central retinal vein occlusion and cilioretinal artery occlusion associated with prolonged retinal arterial fi lling. Am J Ophthalmol 1994;117:308– 13. Hayreh SS. Pathogenesis of occlusion of the central retinal ves- sels. Am J Ophthalmol 1971;72:998–1011. Hayreh SS. Classifi cation of central retinal vein occlusion. Oph- thalmol 1983;90:458–74.
  8. Somers EC, Monrad SU, Warren JS et al. Antinuclear antibody prevalence in a general pediatric cohort from Mexico City: dis- cordance between immunofl uorescence and multiplex assays. Clin Epidemiol 2016 Dec;20:9:1-8.
  9. Shah JH, Salagre KD, Sahay RN et al. Heterozygous MTHFR A1298C Mutation causing Cerebral Venous Sinus Thrombosis. J Assoc Physicians India. 2016 Nov;64(11):76-7.
  10. Fişuş AD, Pop DS, Rusu MB, et al. Nonichemic Central Retinal Vein Occlusion Associated With Hereditary Thrombophylia. Rom J Ophthalmol. 2015 Jul-Sep;59(3):172-6.
  11. Scheufele TA, Pieroni CG, Baumal CR. Methylenetetrahydro- folate reductase gene mutation in a 16-year-old girl with combined central retinal vein occlusion/cilioretinal artery occlusion. Retin Cases Brief Rep. 2007;1(3):134-7.
  12. Lahey JM, Kearney JJ, Tunc M. Hypercoagulable states and central retinal vein occlusion Curr Opin Pulm Med 2003 Sep;9(5):385-92
  13. Fong ACO, Schatz H, McDonald HR et al. Central retinal vein oc- clusion in young adults (papillophlebitis). Retina 1992;12(1):3-11. Gass JDM. Diagnosis and Treatment. 4th ed. St. Louis: CV Mos- by; Stereoscopic atlas of macular diseases; 1997;546–55. Le