Journals / Retina-Vitreus / 2022 / Cilt: 31 - Sayı: 3

The Use of Androgens for Doping in Bodybuilding, and Ocular Side Effects: A Case Report

Pages
278–280
Publication Date
2022-10-17
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusions: This case is important in that it not only contributes to the ongoing debate in the literature that androgen steroids may be a risk factor for CSC formation, but also draws attention to the fact that in addition to known side effects drugs used for doping may have side effects that have not yet been reported.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Purpose: The androgenic steroids drostanolone, boldenone, and stanozolol are used off-label by athletes for doping.
📊
Key Findings & Data:This is the second case reported in the literature who used these steroids as doping for bodybuilding and developed central serous chorioretinopathy (CSC) Cased presentation: A man aged 37 years presented with symptoms of unilateral metamorphopsia, slight central scotoma, and vision loss.
💡
Conclusion & Impact:Conclusions: This case is important in that it not only contributes to the ongoing debate in the literature that androgen steroids may be a risk factor for CSC formation, but also draws attention to the fact that in addition to known side effects drugs used for doping may have side effects that have not yet been reported.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Purpose: The androgenic steroids drostanolone, boldenone, and stanozolol are used off-label by athletes for doping. This is the second case reported in the literature who used these steroids as doping for bodybuilding and developed central serous chorioretinopathy (CSC) Cased presentation: A man aged 37 years presented with symptoms of unilateral metamorphopsia, slight central scotoma, and vision loss. The anamnesis revealed that the patient used steroids (drostanolone enanthate, boldenone undecylenate and stanozolol) for body building. He was diagnosed as having bilateral CSC. The symptoms were relieved in 2 months with of topical nepafenac treatment. Although the patient discontinued androgen steroids, recurrence of CSC observed 6 months later. Conclusions: This case is important in that it not only contributes to the ongoing debate in the literature that androgen steroids may be a risk factor for CSC formation, but also draws attention to the fact that in addition to known side effects drugs used for doping may have side effects that have not yet been reported.

🔖

Cite This Article

ZOR, K. R., KÜÇÜK, E., ÇINAROĞLU, S., BİÇER, G. Y. (2022). The Use of Androgens for Doping in Bodybuilding, and Ocular Side Effects: A Case Report. Retina-Vitreus, Cilt: 31 - Sayı: 3, 278–280. https://ajindex.com/articles/589017

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (15)

  1. Vorona E, Nieschlag E. Adverse effects of doping with anabolic androgenic steroids in competitive athletics, recreational sports and bodybuilding. Minerva Endocrinol 2018; 43: 476-488
  2. Daruich A, Matet A, Dirani A, Bousquet E, Zhao M, Farman N, Jaisser F, Behar-Cohen F. Central serous chorioretinopathy: Recent findings and new physiopathology hypothesis. Prog Retin Eye Res 2015; 48: 82-118
  3. Scarinci F, Ghiciuc CM, Patacchioli FR, Palmery M, Parravano M. Investigating the hypothesis of stress system dysregulation as a risk factor for central serous chorioretinopathy: a literature mini-review. Curr Eye Res. 2019; 44(6): 583-589
  4. Uhumwangho OM, Momoh RO. Central serous chorioretinopathy in Benin City, Nigeria. Ann Afr Med. 2015; 14(4): 163
  5. Loncarek K. Sports medicine update. Scand J Med Sci Sports. 2002; 12(5): 323-323
  6. İslam QU, Hanif MK and Tareen S. Frequency of systemic risk factors in central serous chorioretinopathy. J Coll Physicians Surg Pak 2016; 8: 692-695
  7. Karadimas P and Bozuas EA. Glucocorticoid use represents a risk factor for central serous chorioretinopathy: a prospective, case-control study. Grafes Arch Clin Exp Ophthalmol 2004; 242: 800-802
  8. Georgalas I, Petrou P, Pagoulatos D, et al. Central serous chorioretinopathy in the fellow eye as acomplication of intravitreal dexamethasone implant for the treatment of Irvine- Gass syndrome. Clin Exp Optom 2016; 99: 601-603
  9. Conway MD, Noble JA and Peyman GA. Central serous chorioretinopathy in postmenopausal women receiving exogenous testosterone. Retin Cases Brief Rep 2017; 11: 95-99
  10. Nudleman E, Witmer MT, Kiss S, Williams GA, Wolfe JD. Central serous chorioretinopathy in patients receiving exogenous testosterone therapy. Retina. 2014; 34: 2128-2132
  11. Haimovici R, Rumelt S, Melby J. Endocrine abnormalities in patients with central serous chorioretinopathy. Ophthalmology. 2003; 110: 698-703
  12. Tufan HA, Gencer B and Comez AT. Serum cortisol and testosterone levels in central serous chorioretinopathy. Grafes Arch Clin Exp Ophthalmol 2013; 251: 677-680
  13. Gray A, Feldman HA, McKınlay JB, et al. Age, disease, and changing sex hormone levels in midddle-aged men: results of the Massachusetts male aging study. J Clin Endocrional Metab 1991; 73: 1016-1025
  14. King JA, Rosal MC, Ma Y, et al. Association of stress, hostility and plasma testosterone levels. Neuro Endocrinol Lett 2005; 26: 355-360
  15. Scarinci F, Ghiciuc CM, Patacchioli FR, Palmery M, Parravano M. Inves