Journals / Perinatoloji Dergisi / 2021 / Cilt: 29 - Sayı: 2

Comparison of the pregnancy outcomes of the patients with severe symptoms who received medical treatment for COVID-19 versus the patients with mild-moderate symptoms

COVID-19 için tıbbi tedavi gören ve şiddetli semptomları olan hastalar ile hafif semptomları olan hastaların gebelik sonuçlarının karşılaştırılması

Pages
120–125
Publication Date
2022-10-18
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In our study, there is no difference between mild-moderate and severe groups in terms of maternal and perinatal outcomes.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: COVID-19 has spread all over the world since December 2019.
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Key Findings & Data:The present study aimed to compare pregnant women with severe and mild-moderate COVID-19 symptoms in terms of maternal and perinatal outcomes.
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Conclusion & Impact:In our study, there is no difference between mild-moderate and severe groups in terms of maternal and perinatal outcomes.
🔬Design:Research Article
📍Scope:2019 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: COVID-19 has spread all over the world since December 2019. There is little evidence concerning maternal or perinatal outcomes up to now. The present study aimed to compare pregnant women with severe and mild-moderate COVID-19 symptoms in terms of maternal and perinatal outcomes. Methods: The study group was composed of pregnant patients admitted to our tertiary center with symptoms and diagnosed with severe acute respiratory syndrome Coronavirus 2 (SARS-Cov-2). The patients were categorized into two groups: severe and not severe, and women determined as in the severe disease group were hospitalized. The patients were continued to their routine follow-up, their maternal and perinatal outcomes were recorded. Results: A total of 52 patients were enrolled in the study: 59.6% presented mild-moderate disease and 40.4% presented severe disease. The gestational age at diagnosis of COVID-19 was higher in the patients with severe symptoms than in patients with mild-moderate symptoms (median 20.5 vs 28.0, respectively, p=0.048). There was no difference between those two groups in terms of maternal and perinatal outcomes. Conclusion: Despite the growing number of published studies on COVID-19 in pregnancy, there are insufficient quality data to draw conclusions about the severity of COVID-19 in symptomatic pregnant women and its maternal and neonatal consequences. In our study, there is no difference between mild-moderate and severe groups in terms of maternal and perinatal outcomes.

Özet

Amaç: Aral›k 2019’dan bu yana COVID-19 tüm dünyaya yay›ld›. fiu ana kadar maternal veya perinatal sonuçlarla ilgili olarak elimizde çok az kan›t bulunmaktad›r. Bu çal›flmada, fliddetli ve hafif-orta fliddette COVID-19 semptomlar› olan gebeleri maternal ve perinatal sonuçlar bak›m›ndan karfl›laflt›rmay› amaçlad›k. Yöntem: Çal›flma grubu, fliddetli akut respiratuvar sendrom Koronavirüs 2 (SARS-Cov-2) semptomlar›yla üçüncü basamak merkezimize baflvuran ve tan› alm›fl gebelerden olufltu. Hastalar fliddetli ve fliddetli olmayan fleklinde iki gruba ayr›ld› ve fliddetli hastal› k grubunda oldu¤una karar verilen gebeler hastaneye yat›r›ld›. Hastalar›n rutin takiplerine devam edilerek maternal ve perinatal sonuçlar› kaydedildi. Bulgular: Çal›flmaya toplam 52 hasta dahil edildi, bunlar›n %59.6’s›nda hafif-orta fliddette ve %40.4’ünde fliddetli hastal›k mevcuttu. COVID-19 tan›s› esnas›nda gestasyonel yafl, fliddetli semptomlar› olan hastalarda hafif-orta fliddette semptomu olan hastalardan daha yüksekti (s›ras›yla medyan: 20.5’e karfl› 28.0, p=0.048). Maternal ve perinatal sonuçlar yönünden bu iki grup aras›nda hiçbir fark yoktu. Sonuç: Gebelikte COVID-19 üzerine artan say›da yay›nlanm›fl çal›flmaya ra¤men, semptomatik gebelerde COVID-19’un fliddeti ve maternal ve neonatal sonuçlar› hakk›nda sonuç ç›karmaya yetecek miktarda kaliteli veri bulunmamaktad›r. Çal›flmam›zda, hafiforta fliddette semptomlu grup ile fliddetli semptomlu grup aras›nda maternal ve perinatal sonuçlar yönünden fark yoktu.

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Cite This Article

SALMAN, S., YÜKSEL, S., GENCER, F. K., TUNA, G., NACAR, H. Y. (2022). Comparison of the pregnancy outcomes of the patients with severe symptoms who received medical treatment for COVID-19 versus the patients with mild-moderate symptoms. Perinatoloji Dergisi, Cilt: 29 - Sayı: 2, 120–125. https://ajindex.com/articles/588335

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References (10)

  1. Wastnedge EAN, Reynolds RM, van Boeckel SR, Stock SJ, Denison FC, Maybin JA, et al. Pregnancy and COVID-19. Physiol Rev 2021
  2. 303–18. [PubMed] [CrossRef] 2. Poon LC, Yang H, Kapur A, Melamed N, Dao B, Divakar H, et al. Global interim guidance on coronavirus disease 2019 (COVID-19) during pregnancy and puerperium from FIGO and allied partners: information for healthcare professionals. Int J Gynaecol Obstet 2020
  3. 273–86. [PubMed] [CrossRef] 3. Juan J, Gil MM, Rong Z, Zhang Y, Yang H, Poon LC. Effect of coronavirus disease 2019 (COVID-19) on maternal, perinatal and neonatal outcome: systematic review. Ultrasound Obstet Gynecol 2020
  4. 15–27. [PubMed] [CrossRef] 4. Zaigham M, Andersson O. Maternal and perinatal outcomes with COVID-19: a systematic review of 108 pregnancies. Acta Obstet Gynecol Scand 2020
  5. 823–9. [PubMed] [CrossRef] 5. Wenling Y, Junchao Q, Xiao Z, Ouyang S. Pregnancy and COVID-19: management and challenges. Rev Inst Med Trop Sao Paulo 2020
  6. e62. [PubMed] [CrossRef] 6. Di Mascio D, Khalil A, Saccone G, Rizzo G, Buca D, Liberati M, et al. Outcome od coronavirus spectrum infections (SARS, MERS, COV‹D-19) during pregnancy: a systematic review and meta-analysis. Am J Obstet Gynecol MFM 2020
  7. 100107. [PubMed] [CrossRef] 7. Zeng L, Xia S, Yuan W, Yan K, Xiao F, Shao J, et al. Neonatal early-onset infection with SARS-CoV-2 in 33 neonates born to mothers with COVID-19 in Wuhan, China. JAMA Pediatr 2020
  8. 722–5. [PubMed] [CrossRef] 8. Narang K, Enninga EAL, Gunaratne MDSK, Ibirogba ER, Trad ATA, Elrefaei A, et al. SARS-CoV-2 Infection and COV‹D-19 during pregnancy: a multidisciplinary review. Mayo Clin Proc 2020
  9. 1750–65. [PubMed] [CrossRef] 9. Republic of Turkey Ministry of Health. The recommendations of the Scientific Comitttee regarding pregnant women followup during respiratory infections [Internet]. [Document in Turkish] Ankara: Republic of Turkey Ministry of Health [cited 2020 Oct 16]. Available from: https://covid19.saglik.gov.tr/ Eklenti/39101/0/covid-19solunumsistemihastaliklarininyayginoldugudonemdesaglikkuruluslarindagebetakibipdf. pdf 10. Oakes MC, Kernberg AS, Carter EB, Foeller ME, Palanisamy A, Raghuraman N, et al. Pregnancy as a risk factor for severe coronavirus disease 2019 using standardized clinical criteria. Am J Obstet Gynecol MFM 2021
  10. 3(3):100319. [PubMed] [CrossRef] 11. Ozsurmeli M, Terzi H, Hocaoglu M, Bilir RA, Gunay T, Unsal D, et al. Clinical characteristics, maternal and neonatal outcomes of pregnant women