Journals / Ortadoğu Tıp Dergisi / 2013 / Cilt: 5 - Sayı: 2

Intrathyroidal parathyroid adenoma with two cases

İki olgu nedeniyle intratiroidal paratiroid adenomu

Pages
110–113
Publication Date
2022-10-18
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

This case reports presented to shed some light on the potential preoperative diagnostic difficulties in the rare cases of hyperparathyroidism due to intrathyroidal parathyroid adenoma and to discuss the possible solutions.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:The current trend is toward definitive preoperative localization of parathyroid adenoma in management of patients diagnosed as primary hyperparathyroidism due to parathyroid adenoma.
📊
Key Findings & Data:The first case is a 48-year-old woman presented with hypercalcemia from biochemical hyperparathyroidism and diagnosed preoperatively as intrathyroidal parathyroid adenoma according to the findings obtained thyroid ultrasonography and parathyroid scintigraphy by the protocol using single photon emission computed tomography with technetium-99m sestamibi The diagnosis of primary hyperparathyroidism due to intrathyroidal parathyroid adenoma was confirmed with the followed right lobectomy.
💡
Conclusion & Impact:This case reports presented to shed some light on the potential preoperative diagnostic difficulties in the rare cases of hyperparathyroidism due to intrathyroidal parathyroid adenoma and to discuss the possible solutions.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

The current trend is toward definitive preoperative localization of parathyroid adenoma in management of patients diagnosed as primary hyperparathyroidism due to parathyroid adenoma. However, the similarities in the cytological features of both thyroid and parathyroid lesions make the preoperative differential diagnosis harder. We here present two case reports. The first case is a 48-year-old woman presented with hypercalcemia from biochemical hyperparathyroidism and diagnosed preoperatively as intrathyroidal parathyroid adenoma according to the findings obtained thyroid ultrasonography and parathyroid scintigraphy by the protocol using single photon emission computed tomography with technetium-99m sestamibi The diagnosis of primary hyperparathyroidism due to intrathyroidal parathyroid adenoma was confirmed with the followed right lobectomy. The second case is a 43 year old man with clinical and biochemical hyperthyroidism confirmed by ultrasonography and scintigraphy however it was understood in the postoperative period that the case were not intrathyroidal parathyroid adenoma. This case reports presented to shed some light on the potential preoperative diagnostic difficulties in the rare cases of hyperparathyroidism due to intrathyroidal parathyroid adenoma and to discuss the possible solutions.

Özet

Paratiroid adenomuna bağlı primer hiperparatiroidizm (PHP) tanısı alan hastaların tedavisinde güncel eğilim, adenomun yerleşim yerinin preoperatif dönemde kesin olarak belirlenmesi yönündedir. Ancak, tiroid ve paratiroid lezyonlarının sitolojik özelliklerindeki benzerlikler preoperatif dönemde ayırıcı tanıda zorluk oluşturmaktadır. Bu çalışmada iki olgu sunulmaktadır. İlk olgumuz, hiperkalsemiyle başvuran ve biyokimyasal hiperparatiroidizm tanısı konulan, tiroid ultrasonografisi ve teknesyum-99m sestamibi kullanılarak yapılan tek foton emisyon bilgisayarlı tomografi protokolüne uygun paratiroid sintigrafisi bulgularına göre preoperatif dönemde intratiroidal paratiroid adenomu saptanan 48 yaşındaki bir kadın hastadır. Bu hastada sağ lobektomi ile intratiroidal paratiroid adenomuna bağlı PHP tanısı kesinleştirilmiştir. İkinci olgumuz ise preoperatif dönemde klinik, biyokimyasal hiperparatiroidizm saptanıp ultrasonografi ve sintigrafi ile teyid edilen ancak postoperatif intratiroidal paratiroid adenomu olmadığı anlaşılan 43 yaşında bir erkek hastadır. Bu olgu sunumu, nadir görülen paratiroid adenomuna bağlı hiperparatiroidizm olgularında preoperatif dönemdeki tanısal zorluklara ışık tutmak ve olası çözümleri tartışmak amacıyla sunulmaktadır.

🔖

Cite This Article

KARBEK, B., ÇAKAL, E., GÜLTEKİN, S., ARSLAN, M. S., ÇALIŞKAN, M., DELİBAŞI, T., TOPALOĞLU, O. (2022). Intrathyroidal parathyroid adenoma with two cases. Ortadoğu Tıp Dergisi, Cilt: 5 - Sayı: 2, 110–113. https://ajindex.com/articles/585961

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (16)

  1. Kaplan EL, Yashiro T, Salti G. Primary hyperparathyroidism in 1990s; choice of surgical procedures for this disease. Ann Surg 1992; 215:300-317
  2. Phitayakorn R, McHenry CR. Incidence and location of ectopic abnormal parathyroid glands. Am J Surg 2006; 191:418-423
  3. Roy M, Mazeh H, Chen H, Sippel RS. Incidence and localization of ectopic parathyroid adenomas in previously unexplored patients. World J Surg In Press 2012
  4. Wang C. Hyperfunctioning intrathyroid parathyroid gland. A potential cause of failure in parathyroid surgery. J R Soc Med 1981;74:49-52
  5. Rossi RL, Cady B. Surgery of parathyroid glands. In: Cady B, Rossi RL, editors. Surgery of the thyroid and parathyroid glands. Philadelphia: WB Saunders; 1991, p. 283-294 6. Shen W, Duren M, Morita E. Reoperation for persistent or recurrent primary hyperparathyroidism. Arch Surg 1996;131:861-867
  6. Moore FD, Manting F, Tanasijevic M. Intrinsic limitations to unilateral parathyroid exploration. Ann Surg 1999; 230:382-388
  7. Rao DS, Rao SD. Treatment of primary hyperparathyroidism. Curr Opin Endocrinol Diabetes 2003;37:369-374
  8. Bahar G, Feinmesser R, Joshua BZ, et al. Hyperfunctioning intrathyroid parathyroid gland.: A potential cause of failure in parathyroidectomy. Surgery 2006;139:821-826
  9. Ros S, Sitges-Serra A, Pereira JA, et al. Intrathyroid parathyroid adenomas: Right and lower. Cir Esp 2008;84:196-200
  10. Civelek AC, Ozalp E, Donovan P, Udelsman R. Prospective evaluation of delayed technetium-99m sestamibi SPECT scintigraphy for preoperative localization of primary hyperparathyroidism. Surgery 2002;131:149-157
  11. Moka D, Voth E, Dietlein M, Larena-Avellaneda A, Schicha H. Technetium 99m-MIBI-SPECT: a highly sensitive diagnostic tool for localization of parathyroid adenomas. Surgery 2000; 128:29–35
  12. Billotey C, Sarfati E, Aurengo A, et al. Advantages of SPECT in technetium-99m-sestamibi parathyroid scintigraphy. J Nucl Med 1996; 37:1773–1778
  13. Grisel JJ, Al-Ghawi H, Heubi CH, Steward DL. Successful removal of an intrathyroidal parathyroid adenoma located by technetium Tc 99m sestamibi scan and ultrasound. Thyroid 2009;19:423-425
  14. Balan KK, Wat SY, Seshadri N, et al. A large intrathyroidal parathyroid adenoma presenting as a cold lesion on thyroid scintigraphy. Clin Nucl Med 2007;32:237-238
  15. Yusim A, Aspelund G, Ahrens W, et al. Intrathyroidal parathyroid adenoma. Thyroid 2006;16:619-620
  16. Yabuta T, Tsushima Y, Masuoka H, et al. Ultrasonographic features of int