Journals / Ortadoğu Tıp Dergisi / 2014 / Cilt: 6 - Sayı: 1

A Case of Mediastinitis Due To Multidrug Resistant Acinetobacter Baumannii Recovered With Combined Antibiotic Therapy

Kombine Antibiyotik Tedavisi İle Düzelen Çok İlaca Dirençli Acinetobacter Baumannii Mediastiniti Olgusu

Pages
54–57
Publication Date
2022-10-18
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this case report,we describe a patient who experienced mediastinitis due to A. baumannii infection after coronary artery bypass surgery that was successfully treated with rifampicin and colistin combination.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:(A. baumannii) is a non fermantative gram negative coccobacillus that may cause hospital infections with difficultiesin treatment high mortality rates due to its ability to have multiple drug resistance.
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Key Findings & Data:Postoperative mediastinitis is a rare condition with a high mortality rate.
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Conclusion & Impact:In this case report,we describe a patient who experienced mediastinitis due to A. baumannii infection after coronary artery bypass surgery that was successfully treated with rifampicin and colistin combination.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

(A. baumannii) is a non fermantative gram negative coccobacillus that may cause hospital infections with difficultiesin treatment high mortality rates due to its ability to have multiple drug resistance. During recent years, resistanceto a lot of antimicrobials including carbapenems in A.baumannii strains results in problems in treatment. Antibioticcombinations are suggested in the treatment of infections caused by multi-drug resistant A. baumannii strains. Postoperative mediastinitis is a rare condition with a high mortality rate. The combination of rifampicin and colistin is anappropriate treatment choice in case of mediastinitis caused by multi-drug resistant A. baumannii. In this case report,we describe a patient who experienced mediastinitis due to A. baumannii infection after coronary artery bypass surgery that was successfully treated with rifampicin and colistin combination.

Özet

Acinetobacter baumannii (A. baumannii) çoklu ilaç direnci göstermesi nedeniyle tedavisinde sorunlar yaşananve mortalite oranı yüksek hastane enfeksiyonlarına neden olabilen gram negatif nonfermentatif kokobasildir. Sonyıllarda A.baumannii suşlarında karbapenemler dahil birçok antibiyotik grubuna karşı direnç görülmesi tedavideönemli sorunlara yol açmaktadır. Çoklu ilaca dirençli A. baumanniinin neden olduğu enfeksiyonların tedavisindeçeşitli antibiyotik kombinasyonları önerilmektedir. Postoperatif mediastinit nadir görülen bir komplikasyon olupmortalite oranı yüksektir. Çok ilaca dirençli Acinetobacter baumanniinin neden olduğu mediastinitin tedavisinderifampisin ve kolistin kombinasyonu uygun bir tedavi seçeneğidir. Bu yazıda koroner arter bypass ameliyatı sonrası Acinetobacter baumannii mediastiniti gelişen, kolistin ve rifampisinkombinasyonu ile tedavi başarısı sağlanan bir olgu sunuldu.

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Cite This Article

ALTIN, N., KATIRCIOĞLU, S. F., YAPAR, G. T., BAYRAKTAROĞLU, M. S., ŞENCAN, İ., CESUR, S. (2022). A Case of Mediastinitis Due To Multidrug Resistant Acinetobacter Baumannii Recovered With Combined Antibiotic Therapy. Ortadoğu Tıp Dergisi, Cilt: 6 - Sayı: 1, 54–57. https://ajindex.com/articles/585870

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References (12)

  1. MacIver RH, Stewart R, Frederiksen JW, Fullerton DA, Horvath KA. Topical application of bacitracin ointment is associated with decreased risk of mediastinitis after median sternotomy. Heart Surg Forum. 2006;9:E750-3
  2. Athanassiadi KA. Infections of the mediastinum. Thorac Surg Clin. 2009;19:37-45, 3. Jayakrishnan AG, Allan A, Forsyth AT, Desai JB. Sternal wound infections and internal mammary artery grafts. J Thorac Cardio- vasc Surg. 1993;106:181-2
  3. Baldwin RT, Radovancevic B, Sweeney MS, et al. Bacterial me- diastinitis after heart transplantation. J Heart Lung Transplant. 1992;11(3 Pt 1):545-9
  4. Ioannis K. Toumpoulisa, Nikolaos Theakosb and Joel Dunningc. Does bilateral internal thoracic artery harvest increase the risk of mediastinitis?. Interact CardioVasc Thorac Surg. 2007;6:787-791
  5. Farinas MC, Gald Peralta F, Bernal JM, et al. Suppurative me- diastinitis after open-heart surgery: a case-control study cove- ring a seven-year period in Santander, Spain. Clin Infect Dis. 1995;20:272-9
  6. Milano CA, Kesler K, Archibald N, et al. Mediastinitis after coro- nary artery bypass graft surgery. Risk factors and long-term survi- val. Circulation. 1995;92:2245-51
  7. Ang LB, Veloria EN, Evanina EY, Smaldone A. Mediastinitis and blood transfusion in cardiac surgery: A systematic review. Heart Lung. 2012; 41:255-63
  8. Shaffer HA, Valenzuela G, Mittal RK. Esophageal perforation. A reassessment of the criteria for choosing medical or surgical the- rapy. Arch Intern Med. 1992;152:757-61
  9. Konvalinka A, Errett L, Fong IW. Impact of treating Staphylococ- cus aureus nasal carriers on wound infections in cardiac surgery. J Hosp Infect. 2006; 64:162-8
  10. Pachón-Ibáñez ME, Docobo-Pérez F, López-Rojas R, Domínguez- Herrera J, Jiménez-Mejias ME, García-Curiel A,et al. Efficacy of rifampin and its combinations with imipenem, sulbactam, and co- listin in experimental models of infection caused by imipenem- resistant Acinetobacter baumannii. Antimicrob Agents Chemot- her. 2010;54:1165-72
  11. Dizbay M, Tozlu DK, Cirak MY, Isik Y, Ozdemir K, Arman D. In vitro synergistic activity of tigecycline and colistin against XDR- Acinetobacter baumannii. J Antibiot (Tokyo). 2010; 63:51-3
  12. Timurkaynak F, Can F, Azap OK, Demirbilek M, Arslan H, Kara- man SO.In vitro activities of non-traditional antimicrobials alone or in combination against multidrug-resistant strains of Pseudomo- nas aeruginosa and Acinetobacter baumannii isolated from inten- sive care units. I