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Journals / Nöropsikiyatri Arşivi / 2020 / Cilt: 57 - Sayı: 4

Relationship between Apnea-Hypopnea Index and Oxygen Desaturation inREM-Sleep Period and Morning Headache in Patients with Obstructive SleepApnea Syndrome

Obstruktif Uyku Apne Sendromlu Hastalarda REM Uyku Dönemindeki Apne-Hipopne İndeksi ve Oksijen Desaturasyonu ile Sabah Baş Ağrısı Arasındaki İlişki

Sinan YETKİN
Güray KOÇ
Bülent Devrim AKÇAY
Refah SAYIN
Ömer KARADAŞ
Kübra Mehel METİN
Pages
294–298
Publication Date
2022-10-19
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The minimum oxygen saturation in REM sleep period and total sleep time (TST) was lower in patients with morning headache (REM sleep period: 82%, min-max: 50–94% ; TST: 79%, min-max: 50–97%) in compared to patients without morning headache (REM sleep period: 84%, min-max: 50–93% ; TST: 81%, minmax: 50–90%).Conclusion: Here we demonstrated that higher apnea-hypopnea index and lower oxygen saturation in REM sleep period were associated with morning headache in patients with obstructive sleep apnea syndrome.

📌 3 Key Takeaways

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Objective & Hypothesis:Introduction: In patients with morning headache, REM sleep period decreases though little is known about its physiopathology.
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Key Findings & Data:We evaluate the polysomnographic records of obstructive sleep apnea syndrome (OSAS) patients with the hypothesis that oxygen desaturations may be a better determinant in patients with morning headache, especially those in REM sleep periods.Methods: Patient group (group 1) with a total of 361 patients with OSAS and the controls (group 2) with 107 healthy individuals were evaluated.
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Conclusion & Impact:The minimum oxygen saturation in REM sleep period and total sleep time (TST) was lower in patients with morning headache (REM sleep period: 82%, min-max: 50–94% ; TST: 79%, min-max: 50–97%) in compared to patients without morning headache (REM sleep period: 84%, min-max: 50–93% ; TST: 81%, minmax: 50–90%).Conclusion: Here we demonstrated that higher apnea-hypopnea index and lower oxygen saturation in REM sleep period were associated with morning headache in patients with obstructive sleep apnea syndrome.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Introduction: In patients with morning headache, REM sleep period decreases though little is known about its physiopathology. We evaluate the polysomnographic records of obstructive sleep apnea syndrome (OSAS) patients with the hypothesis that oxygen desaturations may be a better determinant in patients with morning headache, especially those in REM sleep periods.Methods: Patient group (group 1) with a total of 361 patients with OSAS and the controls (group 2) with 107 healthy individuals were evaluated. The presence of morning headache was compared between the groups, and sleep parameters were correlated with morning headache.Results: In group 1, patients with OSAS and morning headache, apneahypopnea index in the REM sleep period (26.7/hour, min-max: 0–108.4/hour) was higher than those in patients without morning headache (17.8/hour, min-max: 0–107.8/hour). The minimum oxygen saturation in REM sleep period and total sleep time (TST) was lower in patients with morning headache (REM sleep period: 82%, min-max: 50–94% ; TST: 79%, min-max: 50–97%) in compared to patients without morning headache (REM sleep period: 84%, min-max: 50–93% ; TST: 81%, minmax: 50–90%).Conclusion: Here we demonstrated that higher apnea-hypopnea index and lower oxygen saturation in REM sleep period were associated with morning headache in patients with obstructive sleep apnea syndrome.

Özet

Amaç: Sabah baş ağrısı olan hastalarda, REM uyku periyoduazalmıştır, ancak fizyopatolojisi hakkında az bilgi mevcuttur. Oksijendesatürasyonunun, özellikle REM uyku dönemlerinde olmak üzere,sabah baş ağrısı olan hastalarda daha belirgin olabileceği hipotezi ileobstruktif uyku apne sendromlu hastaların polisomnografik kayıtlarıincelendi. Yöntem: Toplam 365 hasta (Grup 1) ve kontrol grubu olarak 103birey (Grup 2) değerlendirildi. Gruplar arasında sabah baş ağrısı varlığıkarşılaştırıldı, sabah baş ağrısı olup olmamasına göre gruplar kendiiçlerinde ayrılarak uyku parametreleri açısından ayrıca karşılaştırıldı. Bulgular: Grup 1 içerisinde sabah baş ağrısı olan hastalarda REMdönemindeki apne-hipopne indeksi (26,7/saat, min-maks: 0–108,4/saat),sabah baş ağrısı olmayan gruba göre (17,8/saat, min-maks: 0–107,8/ saat) yüksek bulundu. REM dönemindeki ve toplam uyku zamanındakiminumum oksijen satürasyonu sabah baş ağrısı olan grupta (REM: %82,min-maks: %50–94; toplam: %79, min-maks: %50–97) sabah baş ağrısıolmayan gruba (REM: %84, min-maks: %50–93; toplam: %81, min-maks:%50–90) göre düşük bulundu. Sonuç: Bu çalışmada obstruktif uyku apne sendromlu hastalarda REMuyku dönemindeki yüksek apne hipopne indeksi ve düşük oksijensatürasyonunun sabah baş ağrısı ile ilişkili olduğu bulundu.

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Cite This Article

YETKİN, S., KOÇ, G., AKÇAY, B. D., SAYIN, R., KARADAŞ, Ö., METİN, K. M. (2022). Relationship between Apnea-Hypopnea Index and Oxygen Desaturation inREM-Sleep Period and Morning Headache in Patients with Obstructive SleepApnea Syndrome. Nöropsikiyatri Arşivi, Cilt: 57 - Sayı: 4, 294–298. https://ajindex.com/articles/584620

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References (16)

  1. Sleep-related breathing disorders in adults: recommendations for syndrome definition and measurement techniques in clinical research. The Report of an American Academy of Sleep Medicine Task Force. Sleep 1999
  2. 667– 689.[CrossRef] 2. Young T, Palta M, Dempsey J, Skatrud J, Weber S, Badr S. The occurrence of sleep-disordered breathing among middle-aged adults. N Engl J Med 1993
  3. 1230–1235.[CrossRef] 3. Kripke DF, Ancoli-Israel S, Klauber MR, Wingard DL, Mason WJ, Mullaney DJ. Prevalence of sleep-disordered breathing in ages 40–64 years: a populationbased survey. Sleep 1997
  4. 65–76.[CrossRef] 4. Durán J, Esnaola S, Rubio R, Iztueta A. Obstructive sleep apnea-hypopnea and related clinical features in a population-based sample of subjects aged 30 to 70 yr. Am J Respir Crit Care Med 2001
  5. 685–689.[CrossRef] 5. Bixler EO, Vgontzas AN, Lin HM, Ten Have T, Rein J, Vela-Bueno A, Kales A. Prevalence of sleep-disordered breathing in women: effects of gender. Am J Respir Crit Care Med 2001
  6. 608–613.[CrossRef] 6. Paiva T, Farinha A, Martins A, Batista A, Guilleminault C. Chronic headaches and sleep disorders. Arch Intern Med 1997
  7. 1701–1705. 7. Biondi DM. Headaches and their relationship to sleep. Dent Clin North Am 2001
  8. 685–700. 8. Poceta JS. Sleep-related Headache. Curr Treat Options Neurol 2002
  9. 121– 128.[CrossRef] 9. Benbir Şenel G. Pathophysiology, signs and symptoms in snoring and obstructive sleep apnea syndrome. Turkiye Klinikleri Ear Nose and Throat - Special Topics 2018
  10. 1–8. 10. Headache Classification Subcommittee of the International Headache Society, The International Classification of Headache Disorders: 2nd edition. Cephalalgia 2004
  11. 9–160. 11. Ulfberg J, Carter N, Talbäck M, Edling C. Headache, snoring and sleep apnoea. J Neurol 1996
  12. 621–625.[CrossRef] 12. Ohayon MM. Prevalence and risk factors of morning headaches in the general population. Arch Intern Med 2004
  13. 97–102.[CrossRef] 13. Loh NK, Dinner DS, Foldvary N, Skobieranda F, Yew WW. Do patients with obstructive sleep apnea wake up with headaches? Arch Intern Med 1999
  14. 1765–1768.[CrossRef] 14. Paiva T, Batista A, Martins P, Martins A. The relationship between headaches and sleep disturbances. Headache 1995
  15. 590–596.[CrossRef] 15. Jennum P, Hein HO, Suadicani P, Gyntelberg F. Headache and cognitive dysfunctions in snorers. Arch Neurol 1994
  16. 937–942.[CrossRef] 16. Guilleminault C, Van den Hoed J, Mittler MM. Clinical overview of the sleep apnea syndromes. In: Guil