Journals / Nöropsikiyatri Arşivi / 2022 / Cilt: 59 - Sayı: 2

Treatment of Depression with Vortioxetine in a Patient with Comorbid Major Depressive Disorder and Restless Legs Syndrome: A Case Report

Majör Depresyon Bozukluğu ve Huzursuz Bacaklar Sendromu Eş Tanılı Bir Hastada Depresyonun Vortioksetin ile Tedavisi: Bir Olgu Sunumu

Pages
164–166
Publication Date
2022-10-19
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

In the follow-up examination in the first month after vortioxetine treatment, clinically significant improvement was observed in the patient’s depressive complaints, while a partial reduction in RLS symptoms was observed.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Many case reports have shown that the use of antidepressants can lead to restless legs syndrome (RLS).
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Key Findings & Data:A 59-year-old female patient was admitted to the psychiatry outpatient clinic due to depressive complaints for three months.
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Conclusion & Impact:In the follow-up examination in the first month after vortioxetine treatment, clinically significant improvement was observed in the patient’s depressive complaints, while a partial reduction in RLS symptoms was observed.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Many case reports have shown that the use of antidepressants can lead to restless legs syndrome (RLS). Vortioxetine is a new generation antidepressant with a multimodal mechanism of action on serotonin receptors. In this case report, partial improvement in RLS symptoms after treatment with vortioxetine in a patient with a co-diagnosis of major depressive disorder and restless legs syndrome will be discussed. A 59-year-old female patient was admitted to the psychiatry outpatient clinic due to depressive complaints for three months. In the control examination, it was learned that the patient had complaints of RLS that had been going on for about 20 years. RLS symptoms were increased with selective serotonin reuptake inhibitors (SSRI) used by the patient. In the follow-up examination in the first month after vortioxetine treatment, clinically significant improvement was observed in the patient’s depressive complaints, while a partial reduction in RLS symptoms was observed.

Özet

Antidepresan kullanımının huzursuz bacaklar sendromuna (HBS) yol açabileceği pek çok olgu sunumuyla gösterilmiştir. Vortioksetin, serotonin reseptörleri üzerinde multimodal bir etki mekanizması olan yeni nesil bir antidepresandır. Bu yazıda majör depresyon bozukluğu ve huzursuz bacaklar sendromu eş tanılı bir hastada depresyonun tedavisi için başlanan vortioksetin tedavisi sonrasında HBS semptomlarında görülen kısmi düzelme tartışılacaktır. Elli dokuz yaşındaki kadın hasta üç aydır devam eden depresif yakınmalar nedeniyle psikiyatri polikliniğine başvurdu. Hastanın kontrol muayenesinde yaklaşık yirmi yıldır devam eden HBS’ye ait yakınmaları olduğu öğrenildi. Hastanın kullandığı seçici serotonin geri alım inhibitörleri ile HBS belirtileri artmaktaydı. Hastada vortioksetin tedavisi sonrasında birinci aydaki kontrol muayenesinde depresif yakınmalarında klinik olarak belirgin düzelme saptanırken HBS’ye ait belirtilerde kısmi bir azalma gözlemlenmiştir.

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Cite This Article

YILBAŞ, B. (2022). Treatment of Depression with Vortioxetine in a Patient with Comorbid Major Depressive Disorder and Restless Legs Syndrome: A Case Report. Nöropsikiyatri Arşivi, Cilt: 59 - Sayı: 2, 164–166. https://ajindex.com/articles/584599

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