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Journals / Moment Dergi / 2022 / Cilt: 9 - Sayı: 1

The Effect of Transurethral Resection and BCG Therapy on Cytokine Levels in Non-Muscle Invasive Bladder Cancer

Oktay ÜÇER
Gökhan TEMELTAŞ
Talha MÜEZZİNOĞLU
Zeki ARI
Funda KOSOVA
Pages
154–158
Publication Date
2022-10-18
DOI
—
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⚡ TL;DR(Too Long; Didn't Read)

The mean of preoperative IL-1 and neopterin levels significantly decreased after TURBT (p

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: The present study investigated the effect of treatment on interleukin (IL)-1, IL-6, IL-8, and neopterin levels in patients with non-muscle invasive bladder cancer (NMIBC).
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Key Findings & Data:Materials and Methods: Thirty patients with NMIBC and 30 age-matched controls were included in the study.
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Conclusion & Impact:The mean of preoperative IL-1 and neopterin levels significantly decreased after TURBT (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: The present study investigated the effect of treatment on interleukin (IL)-1, IL-6, IL-8, and neopterin levels in patients with non-muscle invasive bladder cancer (NMIBC). Materials and Methods: Thirty patients with NMIBC and 30 age-matched controls were included in the study. Preoperative, postoperative first control [at two weeks after second transurethral resection of bladder tumor (TURBT)] and the second control (at the end of intravesical immunotherapy) blood samples were analyzed using ELISA to determine IL-1, IL-6, IL-8, and neopterin levels. The mean cytokine levels of the patients were statistically compared and comparing the patients’ and controls’ levels. Results: There were no statistically significant differences between the mean IL-1, IL-6, IL-8, and neopterin levels of the patient and control groups before initial TURBT. In the patient group, there were no statistically significant differences in the IL-6 and IL-8 levels after both TURBT and intravesical Bacillus Calmette-Guérin (BCG) therapy. The mean of preoperative IL-1 and neopterin levels significantly decreased after TURBT (p

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Cite This Article

ÜÇER, O., TEMELTAŞ, G., MÜEZZİNOĞLU, T., ARI, Z., KOSOVA, F. (2022). The Effect of Transurethral Resection and BCG Therapy on Cytokine Levels in Non-Muscle Invasive Bladder Cancer. Moment Dergi, Cilt: 9 - Sayı: 1, 154–158. https://ajindex.com/articles/581649

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