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Journals / Molecular Imaging and Radionuclide Therapy / 2018 / Cilt: 27 - Sayı: 3

Synchronous Hepatocellular Carcinoma and Cholangiocellular Carcinoma on 18F-FDG PET/CT

18F-FDG PET/BT’de Senkron Hepatosellüler Karsinoma ve Kolanjiosellüler Karsinoma

Mehmet AYDIN
Ezgi Başak ERDOĞAN
Ertuğrul TEKÇE
Hacı Mehmet TÜRK
Pages
136–137
Publication Date
2022-10-18
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

To our knowledge, this is the first case report of two histopathologically different primary malignant liver tumors in two distinct segments of the liver detected by PET/CT.

📌 3 Key Takeaways

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Objective & Hypothesis:A 43-year-old male patient presented with a mass lesion on the right liver lobe, segment 5, in radiological imaging and elevated alpha-fetoprotein levels (323 ng/mL) compatible with hepatocellular carcinoma (HCC).
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Key Findings & Data:Positron emission tomography/ computed tomography (PET/CT) images showed background level 18F-FDG uptake in the mass lesion.
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Conclusion & Impact:To our knowledge, this is the first case report of two histopathologically different primary malignant liver tumors in two distinct segments of the liver detected by PET/CT.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

A 43-year-old male patient presented with a mass lesion on the right liver lobe, segment 5, in radiological imaging and elevated alpha-fetoprotein levels (323 ng/mL) compatible with hepatocellular carcinoma (HCC). Positron emission tomography/ computed tomography (PET/CT) images showed background level 18F-FDG uptake in the mass lesion. In addition, a secondary focus of increased 18F-FDG uptake was detected on the left liver lobe, segment 2, approximately 1,5 cm in diameter. Histopathological examination revealed HCC in the larger mass lesion with a lower 18F-FDG uptake, and cholangiocellular carcinoma in the smaller mass lesion with a higher 18F-FDG uptake. To our knowledge, this is the first case report of two histopathologically different primary malignant liver tumors in two distinct segments of the liver detected by PET/CT.

Özet

Radyolojik görüntülemede karaciğer sağ lob segment 5’de hepatosellüler karsinom (HCC) ile uyumlu kitle lezyonu saptanan ve alfa-fetoprotein yüksekliği (323 ng/mL) olan 43 yaşında erkek bir hasta kliniğimize başvurdu. 18F-FDG pozitron emisyon tomografi/bilgisayarlı tomografi (PET/BT) görüntüleri, kitle lezyonda fizyolojik seviyede 18F-FDG tutulumu gösterdi. Ek olarak, sol lob segment 2’de artmış 18F-FDG tutulumu olan, yaklaşık 1,5 cm çapında ikinci bir odak tespit edildi. Histopatolojik incelemede, daha düşük 18F-FDG tutan büyük kitle lezyonda HCC, daha yüksek 18F-FDG tutan küçük kitle lezyonda ise kolanjiosellüler karsinom saptandı. Bildiğimiz kadarıyla bu, PET/BT ile tanısı konulmuş karaciğerin farklı iki segmentinde histopatolojik olarak farklı iki primer malign karaciğer tümörünün bildirildiği ilk olgu sunumudur.

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Cite This Article

AYDIN, M., ERDOĞAN, E. B., TEKÇE, E., TÜRK, H. M. (2022). Synchronous Hepatocellular Carcinoma and Cholangiocellular Carcinoma on 18F-FDG PET/CT. Molecular Imaging and Radionuclide Therapy, Cilt: 27 - Sayı: 3, 136–137. https://ajindex.com/articles/581622

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References (5)

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