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Journals / Molecular Imaging and Radionuclide Therapy / 2020 / Cilt: 29 - Sayı: 2

The Impact of Primary Tumor and Locoregional Metastatic Lymph Node SUVmax on Predicting Survival in Patients with Rectal Cancer

Rektal Kanserli Hastalarda Primer Tümör ve Lokorejyonel Metastatik Lenf Nodu SUVmaks’ın Sağkalım Üzerine Belirleyici Etkisi

Göksel ALÇIN
Yasemin ŞANLI
Gülçin YEĞEN
Esra KAYTAN SAĞLAM
Tevfik Fikret ÇERMİK
Pages
65–71
Publication Date
2022-10-18
DOI
—
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⚡ TL;DR(Too Long; Didn't Read)

Primary tumor SUVmax did not have an effect on predicting survival (p=0.525) howeverlocoregional metastatic lymph node SUVmax had an effect (p

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Objective & Hypothesis:Objectives: The aim of this study was to evaluate the impact of maximum standard uptake value (SUVmax) of the primary tumor and locoregionalmetastatic lymph node in predicting survival in patients with the preoperative rectal adenocarcinoma.Methods: One hundred and fifteen patients [mean age ± standard deviation (SD): 58.7±11.4 years] with biopsy-proven rectal adenocarcinomaunderwent 18F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) imaging for the staging were includedin this study.
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Key Findings & Data:All patients were followed-up for a minimum of 12 months (mean ± SD: 29.7±13.5 months).
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Conclusion & Impact:Primary tumor SUVmax did not have an effect on predicting survival (p=0.525) howeverlocoregional metastatic lymph node SUVmax had an effect (p
🔬Design:Research Article
📍Scope:2017 Verileri
⚙️Variables:Domain Parameters

Abstract

Objectives: The aim of this study was to evaluate the impact of maximum standard uptake value (SUVmax) of the primary tumor and locoregionalmetastatic lymph node in predicting survival in patients with the preoperative rectal adenocarcinoma.Methods: One hundred and fifteen patients [mean age ± standard deviation (SD): 58.7±11.4 years] with biopsy-proven rectal adenocarcinomaunderwent 18F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) imaging for the staging were includedin this study. All patients were followed-up for a minimum of 12 months (mean ± SD: 29.7±13.5 months). Tumor-node-metastasis 2017 clinicalstaging, SUVmax of the primary rectal tumor and locoregional lymph nodes on the PET/CT studies were evaluated.Results: All patients had increased FDG activity of the primary tumor. The mean ± SD SUVmax of the primary tumor and locoregional metastaticlymph node were 21.0±9.1 and 4.6±2.8, respectively. Primary tumor SUVmax did not have an effect on predicting survival (p=0.525) howeverlocoregional metastatic lymph node SUVmax had an effect (p

Özet

Amaç: Çalışmamızın amacı preoperatif rektum adenokanserli olan hastalarda sağkalımı öngörmede primer tümör ve lokorejyonel metastatik lenf nodu maksimum standart alım değeri (SUVmaks) değerinin etkinliğini değerlendirmektir. Yöntem: Bu çalışmaya, biyopsiyle kanıtlanmış rektal adenokarsinoma ile evreleme amaçlı 18F-florodeoksiglikoz (FDG) pozitron emisyon tomografi/ bilgisayarlı tomografi (PET/BT) görüntüleme yapılan 115 hasta [ortalama yaş ± standart sapma (SS): 58,7±11,4 yıl] dahil edildi. Tüm hastalar en az 12 ay (ortalama ± SS: 29,7±13,5 ay) takip edildi. Tümör-nodül-metastaz 2017 klinik evreleme, primer rektal tümör SUVmaks ve lokorejyonel lenf nodu SUVmaksdeğerlendirildi. Bulgular: Tüm hastalarda primer tümöre ait artmış FDG tutulumu saptandı. Primer tümör ve lokorejyonel metastatik lenf nodu ortalama SUVmaks’ları sırasıyla 21,0±9,1 ve 4,6±2,8 idi. Primer tümör SUVmaks’ın sağkalımı öngörmede bir etkisi saptanmamış olup (p=0,525) lokorejyonel metastatik lenf nodu SUVmaks’ın sağkalımı öngörmede etkisi saptandı (p

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Cite This Article

ALÇIN, G., ŞANLI, Y., YEĞEN, G., SAĞLAM, E. K., ÇERMİK, T. F. (2022). The Impact of Primary Tumor and Locoregional Metastatic Lymph Node SUVmax on Predicting Survival in Patients with Rectal Cancer. Molecular Imaging and Radionuclide Therapy, Cilt: 29 - Sayı: 2, 65–71. https://ajindex.com/articles/581563

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