SavedAdd your journal

Journals / MN Oftalmoloji / 2015 / Cilt: 22 - Sayı: 2

Effect of Aging on Retinal Nerve Fiber Layer Ganglion Cell Complex and Central Macular Thickness in Healthy Subjects

Sağlıklı Bireylerde Yaşlanmanın Retina Sinir Lifi Tabakası Ganglion Hücre Kompleksi ve Merkezi Maküla Kalınlığı Üzerindeki Etkisi

Mehmet DEMİR
Zeynep ACAR
Ali OLGUN
Sönmez ÇINAR
Hakan SENSÖZ
Dilek GÜVEN
Pages
94–97
Publication Date
2022-10-17
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Statistical calculations were performed with NCSS (Number Cruncher Statistical System) 2007 Statistical Softwar e (Utah, USA) program for Windows.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: To evaluate the effect of aging on retinal nerve fiber layer thickness (RNFLT), ganglion cell complex thickness (GCCT), and cen- tral macular thickness (CMT) in healthy subjects.
📊
Key Findings & Data:A total of 496 eyes of 248 healthy sub- jects (male: 102, female: 146) were divided into 6 different age groups according to range of their ages.
💡
Conclusion & Impact:Statistical calculations were performed with NCSS (Number Cruncher Statistical System) 2007 Statistical Softwar e (Utah, USA) program for Windows.
🔬Design:Research Article
📍Scope:2007 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: To evaluate the effect of aging on retinal nerve fiber layer thickness (RNFLT), ganglion cell complex thickness (GCCT), and cen- tral macular thickness (CMT) in healthy subjects. Material and Method: This is a Hospital-based cross sectional, prospective and single center study. A total of 496 eyes of 248 healthy sub- jects (male: 102, female: 146) were divided into 6 different age groups according to range of their ages. The mean RNFLT, GCCT, and CMT of all groups were evaluated in relation with age of subjects. RNFL, GCCT and CMT measured with spectral domain optical coherence to- mography (OCT). Statistical calculations were performed with NCSS (Number Cruncher Statistical System) 2007 Statistical Softwar e (Utah, USA) program for Windows. A P value of

Özet

Amaç: Sağlıklı bireylerde yaşlanmanın retina sinir lifi kalınlığı (RSLK), retina ganglion hücre kompleksi kalınlığı (GHKK) ve merkezi ma- küla kalınlığı (MMK) üzerine etkisini incelemek. Gereç ve Yöntem: Bu çalışma hastaneye başvuran sağlıklı bireylerde yapılan göz muayenesi ve tetkiklerine dayanılarak yapıldı. İkiyüz kırksekiz (102 erkek, 146 kadın) sağlıklı bireyin 496 gözü incelendi. Katılımcılar yaş gruplarına göre 6 gruba ayrıldı. Katılımcıların retina si- nir lifi kalınlıkları, ganglion hücre kompleksi kalınlıkları ve merkezi maküla kalınlıkları ile yaşları arasındaki ilişki incelendi. RSLK, GHKK ve MMK ölçümleri spektral domain optik koherans tomografi (OKT) ile yapıldı. İstatistiksel değerlendirme için NCSS (Number Crunche r Statistical System, 2007 Statistical Software, Utah, USA) programı kullanıldı. p

🔖

Cite This Article

DEMİR, M., ACAR, Z., OLGUN, A., ÇINAR, S., SENSÖZ, H., GÜVEN, D. (2022). Effect of Aging on Retinal Nerve Fiber Layer Ganglion Cell Complex and Central Macular Thickness in Healthy Subjects. MN Oftalmoloji, Cilt: 22 - Sayı: 2, 94–97. https://ajindex.com/articles/581496

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (13)

  1. Kiernan DF, Mieler WF, Hariprasad SM. Spectral-domain optical coherence tomography: a comparison of modern high-resolution retinal imaging systems. Am J Ophthalmol 2010
  2. 31 2. Badalà F, Nouri-Mahdavi K, Raoof DA, Leeprechanon N, Law SK, Caprioli J. Optic disc and nerve fiber layer imaging to detect glaucoma. Am J Ophthalmol 2007
  3. Huang J, Wang Q, Savini G. Evaluation of the nerve fiber layer and macula in the eyes of healthy children using spectral-domain opti- cal coherence tomography. Am J Ophthalmol 2012
  4. Leung CK, Yu M, Weinreb RN, et al. Retinal nerve fiber layer im- aging with spectral-domain optical coherence tomography: inter- preting the RNFL maps in healthy myopic eyes. Invest Ophthalmol Vis Sci 2012
  5. Sato A, Fukui E, Ohta K. Retinal thickness of myopic eyes deter- mined by spectralis optical coherence tomography. Br J Ophthalmol 2010
  6. Hwang YH, Kim YY. Correlation between optic nerve head pa- rameters and retinal nerve fibre layer thickness measured by spec- tral-domain optical coherence tomography in myopic eyes. Clin Experiment Ophthalmol 2012
  7. Ooto S, Hangai M, Tomidokoro A, et al. Effects of age, sex, and axial length on the three-dimensional profile of normal macular layer structures. Invest Ophthalmol Vis Sci 2011
  8. Duan XR, Liang YB, Friedman DS, et al. Normal macular thick- ness measurements using optical coherence tomography in healthy eyes of adult Chinese persons: the Handan Eye Study. Ophthalmology 2010
  9. Menke MN, Dabov S, Knecht P, Sturm V. Reproducibility of reti- nal thickness measurements in healthy subjects using spectralis optical coherence tomography. Am J Ophthalmol 2009
  10. Bertuzzi F, Hoffman DC, De Fonseka AM, Souza C, Caprioli J. Concordance of retinal nerve fiber layer defects between fellow eyes of glaucoma patients measured by optical coherence tomog- raphy. Am J Ophthalmol 2009
  11. Kardys A, Weinstock-Guttman B, Dillon M, et al. Cholesterol af- fects retinal nerve fiber layer thickness in patients with multiple sclerosis with optic neuritis. Eur J Neurol 2013
  12. 20(9):1264-71. 12. Mylonas G, Sacu S, Dunavoelgyi R, et al. Macula Study Group.Response of retinal sensitivity to ranibizumab treatment of macular edema after acute branch retinal vein occlusion. Retina 2013
  13. Hsu SY, Ko ML, Linn G, Chang MS, Sheu MM, Tsai RK. Effects of age and disc area on optical coherence tomography me