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Journals / Medicine Science / 2019 / Cilt: 8 - Sayı: 1

The effects of different agents preferred for general anesthesia on lactate and liver enzymes in patients undergoing laparoscopic cholecystectomy

Mehmet SARGIN
Ahmet TOPAL
Mehmet Selçuk ULUER
Eray YAŞAR
Şeref OTELCİOĞLU
Pages
180–185
Publication Date
2022-10-18
DOI
—
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Postoperative AST and ALT values are lower in the Group P, compared to Group S and D (P

📌 3 Key Takeaways

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Objective & Hypothesis:In this study, we aimed to evaluate the effects of different agents used for anesthesia maintenance on liver enzymes and lactate changes in patients undergoing laparoscopic cholecystectomy using CO2 pneumoperitoneum with constant pressure.
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Key Findings & Data:Seventy-five patients planned to undergo laparoscopic cholecystectomy operation have been randomly divided into 3 groups.
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Conclusion & Impact:Postoperative AST and ALT values are lower in the Group P, compared to Group S and D (P
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

In this study, we aimed to evaluate the effects of different agents used for anesthesia maintenance on liver enzymes and lactate changes in patients undergoing laparoscopic cholecystectomy using CO2 pneumoperitoneum with constant pressure. Seventy-five patients planned to undergo laparoscopic cholecystectomy operation have been randomly divided into 3 groups. Liver function tests have been evaluated preoperatively and postoperatively in the 24th hour. Arterial blood samples for lactate level determination were obtained: (T_1) immediately before pneumoperitoneum, (T_2) 10 min after pneumoperitoneum, (T_3) 30 min after pneumoperitoneum, (T_4) 60 min after desufflation of CO2. Patients scheduled to undergo laparoscopic cholecystectomy operation. The possible effects of different agents used for anesthesia maintenance on liver enzymes and lactate changes in patients undergoing laparoscopic cholecystectomy. In comparison of lactate values, there were no differences between the three groups in T_1, T_2 and T_4 measurements (P=0.059, P=0.108, P=0.225). However, in the T_3 measurements, lactate values are lower in the Group P, compared to Group S and D (P=0.001, P=0.001). Postoperative AST and ALT values are lower in the Group P, compared to Group S and D (P

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Cite This Article

SARGIN, M., TOPAL, A., ULUER, M. S., YAŞAR, E., OTELCİOĞLU, Ş. (2022). The effects of different agents preferred for general anesthesia on lactate and liver enzymes in patients undergoing laparoscopic cholecystectomy. Medicine Science, Cilt: 8 - Sayı: 1, 180–185. https://ajindex.com/articles/579737

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