Journals / Medicine Science / 2022 / Cilt: 11 - Sayı: 2

Antimicrobial effective nanoparticles: Mechanisms and recent achievements

Pages
905–913
Publication Date
2022-10-18
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this review, nanoparticles that have antimicrobial, antibiofilm effects, and drug delivery systems are discussed with their effect mechanism and different application fields.

📌 3 Key Takeaways

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Objective & Hypothesis:Multiple drug resistance in bacteria has become one of the most important global public health concerns in the last few decades.
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Key Findings & Data:Considering the long and expensive production processes of a new treatment agent, inexpensive and effective new solutions have become sought after, and it has come to the fore to increase the effectiveness of the existing one and make it effective in the target area.
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Conclusion & Impact:In this review, nanoparticles that have antimicrobial, antibiofilm effects, and drug delivery systems are discussed with their effect mechanism and different application fields.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Multiple drug resistance in bacteria has become one of the most important global public health concerns in the last few decades. Existing antimicrobials could be inadequate in the treatment of infections caused by multiple antibiotics-resistant bacteria. Research on the development of inexpensive and effective antimicrobials has gained importance recently. Nanotechnology is a promising alternative in the development of new antimicrobials, as in other fields of science. The antimicrobial effects of nanoparticles alone and antimicrobiotics bound to nanoparticles on multiple drug-resistant microorganisms will be discussed in detail. As the treatment of resistant microorganisms with existing agents becomes inadequate, new treatment searches have begun. Considering the long and expensive production processes of a new treatment agent, inexpensive and effective new solutions have become sought after, and it has come to the fore to increase the effectiveness of the existing one and make it effective in the target area. Antimicrobial-based metal nanoparticles are used extensively in various cancer types as they are valuable in tumor detection, early diagnosis, and targeted delivery of chemotherapeutic agents. Metal nanoparticles are used as important agents in cancer therapy as they are easily penetrating cells and they are non-toxic to tissues. In this review, nanoparticles that have antimicrobial, antibiofilm effects, and drug delivery systems are discussed with their effect mechanism and different application fields.

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Cite This Article

BAKIRHAN, N. K., ÜNAL, N., ŞAVLUK, M., YÜCEL, Ç. (2022). Antimicrobial effective nanoparticles: Mechanisms and recent achievements. Medicine Science, Cilt: 11 - Sayı: 2, 905–913. https://ajindex.com/articles/579584

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References (12)

  1. https://digitalinsights.qiagen.com/products-overview/discoveryinsights-portfolio/analysis-and-visualization/qiagen-clc-microbialgenomics-module/?cmpid=QDI_GA_CLC&gclid=CjwKCAj wpKCDBhBPEiwAFgBzj5URXdGiSCy-WDVb6wtqo6-Ob_ jlO9sPhTDxF4JJV60uf5CgT5uETBoCo50QA. Antimicrobial resistance. QIAGEN 2. WHO. Antimicrobial resistance. 2021. https://www.who.int/news- room/ fact-sheets/detail/antimicrobial-resistance access date 23.02.2021 3. Ahmed FY, Aly UF, Abd El-Baky RM, Waly NGFM. Comparative study of antibacterial effects of titanium dioxide nanoparticles alone and in combination with antibiotics on MDR pseudomonas aeruginosa strains. Int J Nanomedicine. 2020
  2. 3393–404. 4. Lines MG. Nanomaterials for practical functional uses. J Alloys Compd. 2008
  3. 242–5. 5. Khan II, Saeed K, Khan II. Nanoparticles: Properties, applications and toxicities. Arab J Chem. 2019
  4. 908–31. 6. Borzabadi-Farahani A, Borzabadi E, Lynch E. Nanoparticles in orthodontics, a review of antimicrobial and anti-caries applications. Acta Odontol Scand. 2014
  5. 413–7. 7. Singh P, Kim YJ, Singh H,et al. In situ preparation of water-soluble ginsenoside Rh2-entrapped bovine serum albumin nanoparticles: In vitro cytocompatibility studies. Int J Nanomedicine. 2017
  6. 4073–84. 8. Vallet-Regí M, González B, Izquierdo-Barba I. Nanomaterials as promising alternative in the infection treatment. Int J Mol Sci. 2019
  7. Yin IX, Zhang J, Zhao IS, et al. The antibacterial mechanism of silver nanoparticles and its application in dentistry. Int J Nanomedicine. 2020
  8. 2555–62. 10. Maghimaa M, Alharbi SA. Green synthesis of silver nanoparticles from Curcuma longa L. and coating on the cotton fabrics for antimicrobial applications and wound healing activity. J Photochem Photobiol B Biol. 2020
  9. 111806. 11. Hamouda RA, Hussein MH, Abo-elmagd RA, Bawazir SS. Synthesis and biological characterization of silver nanoparticles derived from the cyanobacterium Oscillatoria limnetica. Sci Rep. 2019
  10. 1–17. 12. Mazur P, Skiba-Kurek I, Mrowiec P, et al. Synergistic ros-associated antimicrobial activity of silver nanoparticles and gentamicin against staphylococcus epidermidis. Int J Nanomedicine. 2020
  11. 3551–62. 13. Santos LM, Stanisic D, Menezes UJ,et al. Biogenic Silver Nanoparticles as a Post-surgical Treatment for Corynebacterium pseudotuberculosis Infection in Small Ruminants. Front Microbiol. 2019
  12. Shaikh S, Nazam N, Rizvi SMD, et al. Mechanistic insights into the antimicrobial actions of metallic nan