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Journals / Medicine Science / 2022 / Cilt: 11 - Sayı: 2

Etiological evaluation and the role of plasma exchange treatment in trombotic microangiopathies: A retrospective analysis from Eastern Anatolia

Mehmet Ali ERKURT
Emin KAYA
Emine HİDAYET
İrfan KUKU
Ayşe UYSAL
İlhami BERBER
Soykan BİÇİM
Ahmet KAYA
Ahmet SARICI
Mustafa ÖZGÜL
Pages
762–765
Publication Date
2022-10-18
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The primary treatment in HELLP syndrome was termination of pregnancy, it was observed in our study that TPE was effective in TTP, HELLP syndrome and snake bites and treatment should be started without delay

📌 3 Key Takeaways

🎯
Objective & Hypothesis:The aim is this study was to make the etiological classification of patients diagnosed with TMA in our region and to statistically evaluate the effect of therapeutic plasma exchange, which we use in treatment, on laboratory recovery and mortality.
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Key Findings & Data:In our study, between 2009-2017, 85 patients diagnosed with TMA in our center evaluated retrospectively.
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Conclusion & Impact:The primary treatment in HELLP syndrome was termination of pregnancy, it was observed in our study that TPE was effective in TTP, HELLP syndrome and snake bites and treatment should be started without delay
🔬Design:Research Article
📍Scope:2009-2017 Verileri
⚙️Variables:Domain Parameters

Abstract

The aim is this study was to make the etiological classification of patients diagnosed with TMA in our region and to statistically evaluate the effect of therapeutic plasma exchange, which we use in treatment, on laboratory recovery and mortality. In our study, between 2009-2017, 85 patients diagnosed with TMA in our center evaluated retrospectively. Thirty- one (36.5%) of our patients were followed up with HELLP, 23 with thrombotic thrombocytopenic purpura (TTP) (27.1%), 20 (23.5%) snake bites, and 11 (12.9%) with atypical hemolytic uremic syndrome (aHUS). TPE treatment was performed in all patients. TPE treatment was found effective in patients with HELLP syndrome, TTP and snake bite and statistically significant improvement was obtained in laboratory parameters (p0.05). Mortality rates were found 9.7%, 21.7%, 27.3%, and 0% in patients with HELLP Syndrome, TTP, aHUS, and snake bite, respectively. The primary treatment in HELLP syndrome was termination of pregnancy, it was observed in our study that TPE was effective in TTP, HELLP syndrome and snake bites and treatment should be started without delay

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Cite This Article

ERKURT, M. A., KAYA, E., HİDAYET, E., KUKU, İ., UYSAL, A., BERBER, İ., BİÇİM, S., KAYA, A., SARICI, A., ÖZGÜL, M. (2022). Etiological evaluation and the role of plasma exchange treatment in trombotic microangiopathies: A retrospective analysis from Eastern Anatolia. Medicine Science, Cilt: 11 - Sayı: 2, 762–765. https://ajindex.com/articles/579562

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