Journals / Medicine Science / 2022 / Cilt: 11 - Sayı: 2

Early warning triad for pulmonary microemboli in COVID-19 pneumonia: Pulmonary artery diameter, D-dimer and NT-proBNP

Pages
775–779
Publication Date
2022-10-18
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

We predict that PAD and concurrent D-dimer with NT-proBNP elevation will enable earlier detection of pulmonary microemboli, determine mortality and prognosis, and help to regulate anticoagulation treatments earlier.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:In COVID-19 patients, thrombotic and fibrinolytic events due to hyperinflammation coexist.
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Key Findings & Data:This causes enlargement of the pulmonary artery trunk, increased D-dimer and proBNP levels.
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Conclusion & Impact:We predict that PAD and concurrent D-dimer with NT-proBNP elevation will enable earlier detection of pulmonary microemboli, determine mortality and prognosis, and help to regulate anticoagulation treatments earlier.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

In COVID-19 patients, thrombotic and fibrinolytic events due to hyperinflammation coexist. This causes enlargement of the pulmonary artery trunk, increased D-dimer and proBNP levels. We studied the correlation of PAD, D-dimer, and NT-proBNP levels. We saw that microemboli can be predicted by using this correlation. 908 patients treated due to Covid-19 were included in the study. The patients were divided into two groups as survivors and mortal and divided into 4 groups according to lung involvement. Demographic, laboratory, and CT data were obtained from the hospital data recording system. When comparing inflammatory parameters, D-Dimer, PAD, NT-proBNP levels, we detected a significant difference between groups. There was a positive correlation between D-dimer, PAD, and NT-proBNP levels. Lung involvement more than 50% significantly increased mortality. The diagnosis of PE in patients with COVID-19 has vital importance. Rapid, reliable, non-invasive, easily accessible and low-cost tests are important in diagnosis. We predict that PAD and concurrent D-dimer with NT-proBNP elevation will enable earlier detection of pulmonary microemboli, determine mortality and prognosis, and help to regulate anticoagulation treatments earlier.

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Cite This Article

KALAYCI, M., AYYILDIZ, H., TİMURKAAN, M., TİMURKAAN, E. S., ALTUNTAŞ, G. (2022). Early warning triad for pulmonary microemboli in COVID-19 pneumonia: Pulmonary artery diameter, D-dimer and NT-proBNP. Medicine Science, Cilt: 11 - Sayı: 2, 775–779. https://ajindex.com/articles/579527

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