Journals / Meandros Medical And Dental Journal / 2021 / Cilt: 22 - Sayı: 1

Clinical and Laboratory Findings ofPaediatric Patients with Brucellosis

Çocukluk Çağı Bruselloz Hastalarının Klinik ve Laboratuvar Bulguları

Pages
63–68
Publication Date
2022-10-18
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In settlements where the disease is common, patients with fever and joint pain should be treated early and the disease should be ruled out.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Brucellosis is the most common bacterial zoonotic disease transmitted via unpasteurised milk and dairy products from infected animals.
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Key Findings & Data:This study aimed to evaluate paediatric patients treated for brucellosis and followed for 2 years.Materials and Methods: The records of 73 patients with childhood brucellosis who had undergone treatment and follow-up for 2 years were retrospectively evaluated.Results: The patient age ranged from 1 to 14 years, with 39 boys (53%) and 34 girls (47%).
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Conclusion & Impact:In settlements where the disease is common, patients with fever and joint pain should be treated early and the disease should be ruled out.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: Brucellosis is the most common bacterial zoonotic disease transmitted via unpasteurised milk and dairy products from infected animals. This study aimed to evaluate paediatric patients treated for brucellosis and followed for 2 years.Materials and Methods: The records of 73 patients with childhood brucellosis who had undergone treatment and follow-up for 2 years were retrospectively evaluated.Results: The patient age ranged from 1 to 14 years, with 39 boys (53%) and 34 girls (47%). Fever (94%) was the first common symptom. Other symptoms, in the order of frequency, were myalgia (80%), arthralgia (75%), fatigue (38%) and anorexia (33%). Complications included sacroiliitis (12%), hemophagocytic lymphohistiocytosis (4%), epididymo-orchitis (1.3%), focal abscess (1.3%) and meningitis (1.3%). Splenomegaly, hepatomegaly and lymphadenopathy (24%, 33% and 5%, respectively) were also reported. Moreover, 18% of the patients had hepatosplenomegaly at initial admission. Dermatological involvement revealed maculopapular rash in 4.1% and petechial rash in 9.6% of patients. Body weight loss was observed in 14% of the cases. In addition, 76.3% and 23.7% of the patients had acute and sub-acute forms, respectively.Conclusion: Brucellosis can display several different clinical presentations. This diversity can lead to diagnostic delay. In settlements where the disease is common, patients with fever and joint pain should be treated early and the disease should be ruled out.

Özet

Amaç: Bruselloz, enfekte hayvanlardan pastörize edilmemiş süt ve süt ürünleriylebulaşan en yaygın bakteriyel zoonotik hastalıktır. Bu çalışmada bruselloz tedavisigören ve 2 yıl boyunca takip edilen pediatrik hastaların değerlendirilmesi amaçlandı. Gereç ve Yöntemler: Çocukluk çağı brusellozlu olan 73 hastanın 2 yıllık süredekitedavi ve takip kayıtları geriye dönük olarak incelendi. Bulgular: Yaşları 4-14 arasında değişen 73 hastanın 39’u erkek (%53) ve 34’ü kız(%47) idi. En sık görülen semptomlar ateş (%94), artralji (%75), miyalji (%80),yorgunluk (%38) ve iştahsızlık (%33) idi. Komplikasyon olarak sakroileit (%12) vehemofagositik lenfohistiyositoz (%4) saptandı ve diğer yaygın komplikasyonlarepididimoorşit (%1,3), fokal apse (%1,3) ve menenjit (%1,3) idi. Splenomegali,hepatomegali ve lenfadenopati sıklıkları sırasıyla %24, %33 ve %5 idi. Çalışmayaalınan olguların %18’inde tanı anında hepatosplenomegali varlığı saptanmıştır.Dermatolojik tutulum üçünde makülopapüler döküntü, yedisinde peteşiyal döküntü şeklindeydi. Olguların %14’ünde kilo kaybı tespit edildi. Akut form %76,3 hastada mevcutken subakut form %23,7 hastada mevcuttu. Sonuç: Bruselloz çok farklı klinik tablolarla ortaya çıkabilir. Hastalığın spektrumundaki bu çeşitlilik tanıda gecikmelere yol açabilir.Hastalığın sık görüldüğü yerleşim yerlerinde ateş ve eklem ağrısı olan hastalarda öncelikli olarak düşünülmeli ve hastalık ekarteedilmelidir.

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Cite This Article

KARAMAN, K., BAŞARANOĞLU, M., SÖNMEZ, B., TUNCER, O., KARAMAN, S., BİTKİN, E. Ç. (2022). Clinical and Laboratory Findings ofPaediatric Patients with Brucellosis. Meandros Medical And Dental Journal, Cilt: 22 - Sayı: 1, 63–68. https://ajindex.com/articles/578950

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