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Journals / Kulak Burun Boğaz Uygulamaları / 2019 / Cilt: 7 - Sayı: 2

Serum and tonsil tissue melatonin levels of patients with chronic tonsillitis

Kronik tonsilitli hastaların serum ve tonsil doku melatonin düzeyleri

Erol Şentürk
Yavuz Selim Yıldırım
Ömer Faruk ÇALIM
Alper YENİGÜN
Şerife Evrim Kepekçi Tekkeli
Orhan ÖZTURAN
Mustafa Volkan KIZILTAŞ
Pages
80–84
Publication Date
2022-10-18
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

High performance liquid chromatography was used forthe determination of melatonin in plasma and tissue samples.Results: The tonsil surface tissue levels of melatonin werelower than the simultaneous plasma levels of melatonin(p

📌 3 Key Takeaways

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Objective & Hypothesis:Objectives: This study aims to compare the serum, tonsil surfaceepithelial tissue and parenchyma levels of melatonin in childrenwho underwent tonsillectomy due to recurrent tonsillitis.Patients and Methods: The study included 33 pediatricpatients (17 males, 16 females; mean age 7.3 years; range, 3 to 10years) scheduled for tonsillectomy surgery.
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Key Findings & Data:Five milliliter venousblood samples and 25 g of two different types of tonsil tissues,parenchyma and capsule were collected from the patients andstored.
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Conclusion & Impact:High performance liquid chromatography was used forthe determination of melatonin in plasma and tissue samples.Results: The tonsil surface tissue levels of melatonin werelower than the simultaneous plasma levels of melatonin(p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objectives: This study aims to compare the serum, tonsil surfaceepithelial tissue and parenchyma levels of melatonin in childrenwho underwent tonsillectomy due to recurrent tonsillitis.Patients and Methods: The study included 33 pediatricpatients (17 males, 16 females; mean age 7.3 years; range, 3 to 10years) scheduled for tonsillectomy surgery. Five milliliter venousblood samples and 25 g of two different types of tonsil tissues,parenchyma and capsule were collected from the patients andstored. High performance liquid chromatography was used forthe determination of melatonin in plasma and tissue samples.Results: The tonsil surface tissue levels of melatonin werelower than the simultaneous plasma levels of melatonin(p

Özet

Amaç: Bu çalışmada tekrar eden tonsilit nedeniyle tonsillektomi geçiren çocuklarda serum, tonsil yüzey epitel doku ve parankim melatonin düzeyleri karşılaştırıldı. Hastalar ve Yöntemler: Çalışmaya tonsillektomi cerrahisi planlanan 33 pediatrik hasta (17 erkek, 16 kız; ort. yaş 7.3 yıl; dağılım, 3-10 yıl) dahil edildi. Hastalardan 5 mL venöz kan örneği ve 25 g iki farklı tonsil doku, parankim ve kapsül toplandı ve saklandı. Plazma ve doku örneklerindeki melatoninin saptanmasında yüksek performanslı sıvı kromatografisi kullanıldı. Bulgular: Tonsil yüzey doku melatonin düzeyleri eş zamanlı plazma melatonin düzeylerinden daha düşük idi (p

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Cite This Article

Şentürk, E., Yıldırım, Y. S., ÇALIM, Ö. F., YENİGÜN, A., Tekkeli, Ş. E. K., ÖZTURAN, O., KIZILTAŞ, M. V. (2022). Serum and tonsil tissue melatonin levels of patients with chronic tonsillitis. Kulak Burun Boğaz Uygulamaları, Cilt: 7 - Sayı: 2, 80–84. https://ajindex.com/articles/576531

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