Journals / Koşuyolu Kalp Dergisi / 2017 / Cilt: 20 - Sayı: 1

Monosit/ Yüksek Dansiteli Lipoprotein Kolesterol Oranı Stabil Anjina Pektorisi Olan Hastalarda Safen Ven Greft Açıklığını Öngördürebilir mi?

Does Monocyte/High-Density Lipoprotein Cholesterol Ratio Predict Saphenous Vein Graft Patency in Patients with Stable Angina Pectoris?

Pages
7–12
Publication Date
2022-10-18
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

MHR was not a predictive factor of SVGD.

📌 3 Key Takeaways

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Objective & Hypothesis:Introduction: Circulating monocyte count is a predictive factor of new atherosclerotic plaque development.
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Key Findings & Data:We aimed to investigate the relationship between MHR and saphenous vein graft disease (SVGD).Patients and Methods: A total of 3 69 patients were divided into 3 groups (positive SVGD group= 150, negative SVGD group= 89, normal coronary artery group= 130).
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Conclusion & Impact:MHR was not a predictive factor of SVGD.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Introduction: Circulating monocyte count is a predictive factor of new atherosclerotic plaque development. In addition, there is a strong inverse relationship between high-density lipoprotein (HDL) cholesterol and atherosclerosis. It has been shown that the monocyte/HDL cholesterol ratio (MHR) is a novel inflammatory marker. We aimed to investigate the relationship between MHR and saphenous vein graft disease (SVGD).Patients and Methods: A total of 3 69 patients were divided into 3 groups (positive SVGD group= 150, negative SVGD group= 89, normal coronary artery group= 130). Baseline characteristics and laboratory parameters were recorded and compared among the groups. Results: There were no significant differences between the positive and negative SVGD groups, except for age of SVG and left ventricular ejection fraction, according to baseline characteristics. C-reactive protein (CRP) levels, fasting blood glucose levels and mean platelet volume were higher in the positive SVGD group than in the negative SVGD group (p= 0.008, 0.048 and 0.042, respectively). MHR was not significantly different between the positive and negative SVGD groups (p= 0.169) and normal coronary artery group (p= 0.364). CRP was found to be an independent predictor factor of SVGD.Conclusion: There was no association between MHR and coronary atherosclerosis. MHR was not a predictive factor of SVGD.

Özet

Giriş: Dolaşımdaki monosit sayısı yeni aterosklerotik plak gelişimi için öngördürücü bir faktördür. Ayrıca, yüksek dansiteli lipoprotein kolesterol (HDL) ile ateroskleroz arasında güçlü bir ters ilişki vardır. Monosit sayısı/HDL oranının (MHR) yeni bir inflamatuvar belirteç olduğu gösterilmiştir. Biz MHR ile safen ven greft hastalığı (SVGD) arasındaki ilişkiyi araştırmayı amaçladık.Hastalar ve Yöntem: Toplam 369 hasta 3 gruba bölündü (SVGD olan grup= 150, SVGD olmayan grup= 89, normal koroner arter grubu= 130). Bazal karakteristikler ve laboratuvar parametreleri kayıt edildi ve gruplar arasında karşılaştırıldı.Bulgular: Bazal karakteristiklere göre SVGD olan ve olmayan gruplarda, SVG yaşı ve sol ventrikül ejeksiyon fraksiyonu haricinde istatistiksel farklılık yoktu. C-reaktif protein, açlık kan şekeri ve ortalama platelet hacmi SVGD olan grupta SVGD olmayan gruba göre daha yüksekti (sırasıyla p değerleri= 0.008, 0.048 ve 0.042). MHR değeri SVGD olan, SVGD olmayan (p= 0.169) ve normal koroner arter grupları (p= 0.364) arasında istatistiksel farklılık göstermedi. CRP, SVGD için bağımsız öngördürücü faktör olarak bulundu.Sonuç: MHR ve koroner ateroskleroz arasında ilişki yoktu. MHR, SVGD için bir öngördürücü faktör değildi.

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Cite This Article

BİÇER, H., ALSANCAK, Y., YAŞAR, A. S., SİVRİ, H. D. Ç., ALİ, S., SİVRİ, S., BİLGE, M. (2022). Monosit/ Yüksek Dansiteli Lipoprotein Kolesterol Oranı Stabil Anjina Pektorisi Olan Hastalarda Safen Ven Greft Açıklığını Öngördürebilir mi?. Koşuyolu Kalp Dergisi, Cilt: 20 - Sayı: 1, 7–12. https://ajindex.com/articles/576069

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