Journals / KONURALP TIP DERGİSİ / 2021 / Cilt: 13 - Sayı: 2

The Role of Early Period ERCP in Acute Biliary Pancreatitis?

Akut Bilier Pankreatitte Erken Dönem ERCP’nin Rolü?

Pages
242–250
Publication Date
2022-10-18
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

All patients had acuteonset abdominal pain and serum amylase levels have been ranging between (1012-7660UI/L).Conclusions: In patients with mild acute biliary pancreatitis, there is no significant differencein the early (first 72 hours) ERCP/ES results compared to the results of patients withERCP/ES in the late period.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: Acute pancreatitis;It can be defined as a clinical picture that occurs as a result ofnon_bacterial inflammation of the pancreas and may progress with pathological findings.
📊
Key Findings & Data:For years, various studies have been conducted on the use of EndoscopicRetrograde Cholangiopancreotography and Endoscopic Sphincterotomy for therapeuticpurpose in Acute Pancreatitis.In our study, we aimed to examine either the effectiveness of Endoscopic RetrogradeCholangiopancreotography and Endoscopic Sphincterotomy in patients with mild severity,and how the endoscopic procedure affects the course of the disease.Methods: In this study, patients with mild pancreatitis were selected among the patients whoapplied to the Department of General Surgery, of Atatürk University Faculty of Medicine anddiagnosed with acute biliary pancreatitis (ABP).After the patients were separated according to the mild pancreatitis, early (within 72 hours)and late period, they were randomly selected to be performed Endoscopic RetrogradeCholangiopancreotography and Endoscopic Sphincterotomy. 59 patients were detected in thisway.Results: Twelve (20.3%) of the patients included in our study were male, and 47 (79.7%)were female, and their ages were between 25-75 years (mean 64.3 years).
💡
Conclusion & Impact:All patients had acuteonset abdominal pain and serum amylase levels have been ranging between (1012-7660UI/L).Conclusions: In patients with mild acute biliary pancreatitis, there is no significant differencein the early (first 72 hours) ERCP/ES results compared to the results of patients withERCP/ES in the late period.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: Acute pancreatitis;It can be defined as a clinical picture that occurs as a result ofnon_bacterial inflammation of the pancreas and may progress with pathological findings. Foryears, various studies have been conducted on the use of Endoscopic RetrogradeCholangiopancreotography and Endoscopic Sphincterotomy for therapeutic purpose in AcutePancreatitis. For years, various studies have been conducted on the use of EndoscopicRetrograde Cholangiopancreotography and Endoscopic Sphincterotomy for therapeuticpurpose in Acute Pancreatitis.In our study, we aimed to examine either the effectiveness of Endoscopic RetrogradeCholangiopancreotography and Endoscopic Sphincterotomy in patients with mild severity,and how the endoscopic procedure affects the course of the disease.Methods: In this study, patients with mild pancreatitis were selected among the patients whoapplied to the Department of General Surgery, of Atatürk University Faculty of Medicine anddiagnosed with acute biliary pancreatitis (ABP).After the patients were separated according to the mild pancreatitis, early (within 72 hours)and late period, they were randomly selected to be performed Endoscopic RetrogradeCholangiopancreotography and Endoscopic Sphincterotomy. 59 patients were detected in thisway.Results: Twelve (20.3%) of the patients included in our study were male, and 47 (79.7%)were female, and their ages were between 25-75 years (mean 64.3 years). Two groups werecreated in order to perform ERCP/ES in the early and late periods. All patients had acuteonset abdominal pain and serum amylase levels have been ranging between (1012-7660UI/L).Conclusions: In patients with mild acute biliary pancreatitis, there is no significant differencein the early (first 72 hours) ERCP/ES results compared to the results of patients withERCP/ES in the late period.

Özet

Amaç: Akut pankreatit; Pankreasın bakteriyel olmayan enflamasyonu sonucu patolojikbulgularla seyredebilen klinik bir tablo olarak tanımlanabilir. Yıllardan beri EndoskopikRetrograd Kolanjiopankreatikografi ve Endoskopik Sfinkterotomi’nin Akut Pankreatit’deterapötik maksatlı olarak kullanımı ile ilgili çeşitli çalışmalar yapılmaktadır. Bu çalışmalaragöre özellikle hafif şiddetli Akut Pankreatit’de erken Endoskopik RetrogradKolanjiopankreatikografi ve Endoskopik Sfinkterotomi tartışmalı olmaya devam etmektedir.Biz çalışmamızda hafif şiddetteki Akut Pankreatit’li hastalarında, Endoskopik RetrogradKolanjiopankreatikografi ve Endoskopik Sfinkterotomi’nin tedavideki etkinliğini, aynızamanda yapılan endoskopik işlemin hastalığın seyrini nasıl etkilediğini araştırmayıamaçladık.Gereç ve Yöntem: Bu çalışmada, Atatürk Üniversitesi Tıp Fakültesi Genel Cerrahi AnabilimDalına, akut bilier pankreatit (ABP) tanısı ile müracaat eden hastalar arasından, Ransonkriterleri ve hastaların klinik durumlarına göre hafif şiddetteki pankreatitli hastalar belirlendi.Hastalar hafif pankreatit tablosuna göre ayrıldıktan sonra erken (72 saat içinde) ve geçdönemde, Endoskopik Retrograd Cholangiopancreotography ve Endoskopik Sfinkterotomiyapılmak üzere randomize bir şekilde seçildi. Bu şekilde 59 hasta tespit edildi. Bulgular: Çalışmamıza dahil edilen hastaların 12’si (%20,3 ) erkek, 47’si (%79,7) kadınolup, yaşları 25–75 yıl (ortalama 64,3 yıl) idi. Hastalara erken ve geç dönemde ERCP/ESyapılmak üzere 2 grup oluşturuldu. Hastaların 24(%40,6)’üne erken 35(%59,4)’ine geçdönemde ERCP/ES yapıldı. Tüm hastalarda akut başlayan karın ağrısı vardı ve serum amilazseviyeleri (1012-7660 Üİ/L) arasında değişmekte idi.Sonuç: Hafif şiddetteki akut bilier pankreatitli hastalarda erken (ilk 72 saat)ERCP/ESsonuçlarının geç dönemde ERCP/ES yapılan hastaların sonuçları ile karşılaştırıldığındaanlamlı bir fark yoktur. Bu nedenle hafif şiddetteki akut bilier pankreatitli hastalara erkendönemde ERCP/ES yapılabileceği kanaatindeyiz

🔖

Cite This Article

PEKER, K., YILDIRGAN, M. İ., ASLAN, S. (2022). The Role of Early Period ERCP in Acute Biliary Pancreatitis?. KONURALP TIP DERGİSİ, Cilt: 13 - Sayı: 2, 242–250. https://ajindex.com/articles/575488

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (14)

  1. Leung PS. Overview of the pancreas. Adv Exp Med Biol. 2010;690:3-12
  2. Walsh MK. Diagnosis, prognosis, and treatment of acute pancreatitis. Am Fam Physician. 2008;77(5):594
  3. Portelli M, Jones CD. Severe acute pancreatitis: Pathogenesis, diagnosis and surgical management. Hepatobiliary Pancreat Dis Int. 2017;16(2):155-59
  4. Büchler MW, Gloor B, Müller CA, Friess H, Seiler CA. Uhl W. Acute necrotizing pancreatitis: Treatment strategy according to the status of infection. Ann Surg. 2000;232:619–26. 5. van Santvoort HC, Besselink MG, de Vries AC, Boermeester MA, Fischer K, Bollen TL, et al. Early endoscopic retrograde cholangiopancreatography in predicted severe acute biliary pancreatitis: A prospective multicenter study. Ann Surg. 2009;250(1):68-75
  5. Rosseland AR, Solhaug JH. Early or delayed endoscopic papillotomy (EPT) in gallstone pancreatitis. Ann. Surg. 1984;199(2):165-7
  6. Alfred DR, Ira MJ. Evaluation of the pattern of liver tests and yield of cholangiography in symptomatic choledocholitiasis. Gastrointestinal Endoscopy. 1997;45:394-9
  7. Dursun M, Yılmaz Ş, Canoru F, Batum S, Kaplan A. Akut pankreatitli olgularımızın analizi. Dicle Tıp Dergısi. 2001;28(2):19-27
  8. Naruse, S. Molecular pathophysiology of pancreatitis. Internal Medicine. 2003;42(3): 288-9
  9. Ergüney S, Çiçek Y. Tıkanma sarılığı endoskopik tedavi. In: Hutcheon DF, Kafonek DR. trans. Güncel BY. Cerrahi tedavi. İstanbul: Avrupa Tıp Kitapçılık Ltd. Şti.; 2001. p. 477-80
  10. Lin C, Simon L, Bruce ES, Roger JL, Katayoun T, Christian V. Preoperative versus postoperative endoscopic retrograde cholangiopancreatography in mild to moderate gallstone pancreatitis: A prospective randomized trial. Annals of Surgery. 2000;231(1):82–7
  11. Stefan H, Markus S, Valentin R, Pierre-Alain C. Evidence-based treatment of acute pancreatitis: A look at established paradigms. Ann Surg. 2006;243(2):154–68
  12. Nomura T, Shirai Y, Wakai T, Yokoyama N, Sakata J, Hatakeyama K. Narrow portion of the terminal choledochus is a cause of upstream biliary dilatation in patients with anomalous union of the pacreatic and biliary ducts. Wold J Gastroenterol. 2005;11(41):6503-7
  13. Yuk-Pang Y, Siu-Fai L, Andrew Wai-Chun Y. Role of ERCP in the management of predicted mild acute biliary pancreatitis. Asian J Surg. 2003;26(4):197–201
  14. Mikó A, Vigh É, Mátrai P, Soós A, Garami A, Balaskó M, et al. Computed tomography severity index vs. other indices in the prediction of severity and mortality in acute pancreati