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Journals / KONURALP TIP DERGİSİ / 2022 / Cilt: 14 - Sayı: 1

The Role of Some Parameters in Diagnosis in the Absence of PCR in the Children with COVID-19

COVID-19’lu Çocuklarda PCR Yokluğunda Tanıda Bazı Laboratuvar Parametrelerinin Rolü

Abdullah Solmaz
Tuğba ERAT
Filiz SOLMAZ
Tuğba Meliha Fatma Ercan
Pages
152–160
Publication Date
2022-10-18
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

There were significant differences between the two groups in terms of white blood cell (WBC) (p

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: Infectious diseases cause inflammation in the human body and produce numerical and functional changes in peripheral blood cells.
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Key Findings & Data:Coronavirus disease-19 (COVID-19) is also an infectious disease diagnosed by the Polymerase Chain Reaction (PCR) test.
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Conclusion & Impact:There were significant differences between the two groups in terms of white blood cell (WBC) (p
🔬Design:Modeling & Simulation
📍Scope:Comprehensive Sample
⚙️Variables:COVİD-19 · çocuk · laboratuvar parametreleri

Abstract

Objective: Infectious diseases cause inflammation in the human body and produce numerical and functional changes in peripheral blood cells. Coronavirus disease-19 (COVID-19) is also an infectious disease diagnosed by the Polymerase Chain Reaction (PCR) test. However, PCR testing may not always be available. The aim of this study is to show the effect of numerical and functional changes in blood parameters on the diagnosis of COVID-19 in children. Method: In this retrospective study, 296 patients and 286 healthy children were included. Nasopharyngeal swabs were collected. The swabs were analyzed by Real-time PCR. Independent-t/Mann-Whitney-U tests were applied; Receiver Operating Characteristic (ROC) curves and logistic regression modelling were evaluated. Result: Gender and age distributions of the groups were similar (p>0.05). There were significant differences between the two groups in terms of white blood cell (WBC) (p

Özet

Amaç: Enfeksiyon hastalıkları vücutta inflamasyon oluşturarak periferik kan hücrelerinde sayısal ve fonksiyonel değişikliklere neden olur. Coronavirüs hastalığı-19 (COVID-19), Polimeraz Zincir Reaksiyonu (PCR) testinin ile teşhis edilen bulaşıcı bir hastalıktır. Ancak PCR testi her zaman temin edilemeyebilir. Bu çalışmanın amacı, çocklarda kan parametrelerindeki sayısal ve fonksiyonel değişikliklerin PCR olmadığı durumda COVID-19 hızlı teşhisine etkisini değerlendirmektir. Metod: Çalışmaya 296 COVID-19 hasta ve 286 sağlıklı çocuk dahil edildi. Bilimsel araştırma için gereken izinler alındı. Değişkenlerin normal dağılımına uygunluğuna göre aanalizlerde bağımsız-t veya Mann-Whitney-U testleri uygulandı. Receiver Operating Characteristic (ROC) eğrileri ve lojistik regresyon modellemesi değerlendirildi. Bulgular: Grupların cinsiyeti ve yaşı benzerdir (p>0.05). Beyaz küre (WBC) (p

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Cite This Article

Solmaz, A., ERAT, T., SOLMAZ, F., Ercan, T. M. F. (2022). The Role of Some Parameters in Diagnosis in the Absence of PCR in the Children with COVID-19. KONURALP TIP DERGİSİ, Cilt: 14 - Sayı: 1, 152–160. https://ajindex.com/articles/575463

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