Journals / Klinik Psikofarmakoloji Bülteni / 2013 / Cilt: 23 - Sayı: 2

Fluoksetin ile hipomanik kayma gelişen buli- mik bir hasta: Olgu sunumu

Fluoxetine induced hypomanic shift in a bulimic patient: Case report

Pages
183–185
Publication Date
2022-10-17
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

A BN patient being treated with an antidepressant, who experienced a manic shift risk and comorbid mood disorder which may cause resistance to treatment, are discussed in this case.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Use of antidepressant doses of fluoxetine for mood and anxiety disorders is known to cause manic or hypomanic shifts.
📊
Key Findings & Data:High doses of fluoxetine increase the possibility of manic or hypomanic shifts.
💡
Conclusion & Impact:A BN patient being treated with an antidepressant, who experienced a manic shift risk and comorbid mood disorder which may cause resistance to treatment, are discussed in this case.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Use of antidepressant doses of fluoxetine for mood and anxiety disorders is known to cause manic or hypomanic shifts. Fluoxetine should be used at higher doses for pharmacological treatment of bulimia nervosa (BN) than those used for an antidepressant effect. High doses of fluoxetine increase the possibility of manic or hypomanic shifts. In cases of comorbidity of BN and mood disorder, fluoxetine treatment is becomes more risky in terms of the occurrence of a manic shift. During the use of fluoxetine 60 mg by a patient with BN, who had no history of bipolar disorder or family history of bipolarity, a hypomanic shift occurred. A BN patient being treated with an antidepressant, who experienced a manic shift risk and comorbid mood disorder which may cause resistance to treatment, are discussed in this case.

Özet

Fluoksetinin mizaç ve anksiyete bozukluklarında antidepresan dozlarda kullanımıyla manik veya hipomanik kaymaya neden olabildiği bilinmektedir. BulimiyaNervoza (BN)’nın farmakolojik tedavisinde antidepresanetki için kullanılan dozlardan daha yüksek dozlarda fluoksetin kullanılması gerekmektedir. Yüksek doz fluoksetin kullanıldığında manik veya hipomanik kaymaların görülme ihtimali artmaktadır. Mizaç bozukluğu ekhastalığı varlığında BN‘nin fluoksetinle tedavisi manikkayma açısından daha riskli hale gelmektedir. Bipolar bozukluk öyküsü olmayan ve aile öyküsünde de bipolarite saptanmayan BN hastasında 60 mg fluoksetin kullanımı sırasında hipomanik kayma gelişmiştir. BNhastalarında antidepresan ilaç kullanımı, manik kaymariski ve komorbid mizaç bozukluğunun tedaviye direnç oluşturabilmesi vaka bağlamında tartışılmıştır.

🔖

Cite This Article

EROL, A., OZTEN, M. (2022). Fluoksetin ile hipomanik kayma gelişen buli- mik bir hasta: Olgu sunumu. Klinik Psikofarmakoloji Bülteni, Cilt: 23 - Sayı: 2, 183–185. https://ajindex.com/articles/574097

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (15)

  1. Walsh BT, Pharmacotherapy of eating disorders. Brownell KD,Fairburn CG(eds) Eating Disorders and Obesity. New York The Guilford Press,1995. p.313-317
  2. American Psychiatric Association. Practice guideline for the treatment of patients with eating disorders, third edition. Am J Psychiatry 2006;163(7 suppl):S4-S54
  3. Lebegne B. Mania induced by fluoxetine. Am J Psychiat 1987;144(12):1620
  4. Settle EC Jr, Settle GD. A case of mania associated with fluoxetine. Am J Psychiat 1984;141(12):280-1
  5. Damodaran SS, Khanna R. Fluoxetıne induced mania in an adolescent: possible implications. Indian J Psychiat 1992;34(4):395-6
  6. Turner SM, Jacob RG, Beidel DC, Griffin S. A second case of mania associated with fluoxetine. Am J Psychiat 1988;142(2):274-5
  7. Nakra BR, Szwabo P, Grossberg GT. Mania induced by Fluoxetine. Am J Psychiatry, 1989;146(11):1515-6
  8. Bulik CM. Anxiety, depression, and eating disorders. In: Fairburn CG, Brownell KD, eds. Eating Disorders and Obesity: A Comprehensive Handbook. New York, NY: The Guilford Press; 2002
  9. Herzog DB, Nussbaum KM, Marmor AK. Comorbidity and outcome in eating disorders. Psychiatr Clin North Am 1996;19(4):843-59
  10. Kay WH, Bulik CM, Thornton L, Barbarich N, Masters K. Comorbidity of anxiety disorders with anorexia and bulimia nervosa. Am J Psychiatry 2004;161(12):2215-21
  11. Milos G, Spindler A, Schnyder U. Psychiatric comorbidity and Eating Disorder Inventory (EDI) profiles in eating disorder patients. Can J Psychiatry 2004;49(3):179-84
  12. Blinder BJ, Chaitin BF, Goldstein R, eds. The Eating Disorders: Medical and Psychological Bases of Diagnosis and Treatment. New York, NY: PMA Publications; 1988. p. 101-7
  13. Erol A. Eating disorders and bipolar disorders comorbidity. Journal of Mood Disorders 2011;1(2):75-80. (Turkish
  14. Tondo L, Vázquez G, Baldessarini RJ. Mania associated with antidepressant treatment: comprehensive meta-analytic review. Acta Psychiatr Scand 2010:121(6):404-14
  15. Brewerton TD, Lydiard RB, Herzog DB, Brotman AW, O’Neil PM, Ballenger JC. Comorbidity of axis I psychiatric disorders in bulimia nervosa. J Clin Psychiatry 1995;56(2):77-80.