Journals / Klinik Psikiyatri Dergisi / 2021 / Cilt: 24 - Sayı: 3

The relationship between anxiety and serum Urotensin-II and S100B levels in patients with essential hypertension

Esansiyel hipertansiyonlu hastalarda anksiyete ile serum ürotensin-II ve S100B seviyeleri arasındaki ilişki

Pages
315–323
Publication Date
2022-10-17
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Results: A positive correlation was determinedbetween depression and anxiety scores, and systolicblood pressure (p=0.049, r= 0.160; p

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: In hypertensive people, some biochemicalparameters that are associated with oxidative stress andendothelial functions may play a role in the manifestation of anxiety symptoms, and even in the intensificationof clinical symptoms of the disease.
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Key Findings & Data:The purpose of ourcorrelative study is to examine the association betweenanxiety severity and levels of oxidative stress parametersof Urotensin-II and S100B protein in patients with essential hypertension.
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Conclusion & Impact:Results: A positive correlation was determinedbetween depression and anxiety scores, and systolicblood pressure (p=0.049, r= 0.160; p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: In hypertensive people, some biochemicalparameters that are associated with oxidative stress andendothelial functions may play a role in the manifestation of anxiety symptoms, and even in the intensificationof clinical symptoms of the disease. The purpose of ourcorrelative study is to examine the association betweenanxiety severity and levels of oxidative stress parametersof Urotensin-II and S100B protein in patients with essential hypertension. Method: A total of 153 patients, whohave applied Sociodemographic and Clinical Data Form,Beck Anxiety Inventory (BAI), Beck Depression Inventoryand venous blood samples were taken after blood pressure measurement. S100B and Urotensin-II levels weremeasured with Enzyme-Linked Immunosorbent Assaymethod. Results: A positive correlation was determinedbetween depression and anxiety scores, and systolicblood pressure (p=0.049, r= 0.160; p

Özet

Amaç: Hipertansiyonlu bireylerde anksiyete bulgularının ortaya çıkmasında hatta hastalığın klinik bulgularının şiddetlenmesinde oksidatif stresle ve endotel fonksiyonlarıyla ilişkili olan bazı biyokimyasal parametrelerin rolü olabilir. Çalışmamızda, esansiyel hipertansiyon hastalarının anksiyete düzeyleri araştırılarak, anksiyete şiddetinin oksidatif stres parametrelerinden olan Ürotensin-II ve S100B protein seviyeleri üzerindeki etkisinin incelenmesi amaçlanmıştır. Yöntem: Çalışmaya, kan basıncı ölçümleri sonrasında venöz kan örnekleri alınan ve Sosyodemografik ve Klinik Veri Formu, Beck Anksiyete Ölçeği (BAÖ), Beck Depresyon Ölçeği (BDÖ) ölçekleri uygulanan 153 hasta dahil edildi. EnzymeLinked Immunosorbent Assay (ELISA) yöntemi ile S100B ve Ürotensin-II düzeyleri ölçüldü. Bulgular: Depresyon ve anksiyete puanları ile sistolik kan basıncı arasında pozitif yönde bir korelasyon bulunmaktaydı (p=0.049, r= 0.160; p

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Cite This Article

KORKMAZ, H., TELO, S., YILDIZ, S., ATMACA, M., KORKMAZ, S., KAZĞAN, A. (2022). The relationship between anxiety and serum Urotensin-II and S100B levels in patients with essential hypertension. Klinik Psikiyatri Dergisi, Cilt: 24 - Sayı: 3, 315–323. https://ajindex.com/articles/573810

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