Journals / Klimik Dergisi / 2011 / Cilt: 24 - Sayı: 2

A case of multidrug-resistant tuberculosis of the lung and breast due to intrafamilial transmission

Aile içi bulaşma sonucu ortaya çıkan çok ilaca dirençli akciğer ve meme tüberkülozu olgusu

Pages
119–121
Publication Date
2022-10-18
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

As this case demonstrated that family screening is important for finding new patients, and tuberculous mastitis, albeit rare, should be considered in the differential diagnosis of chronic breast infections with unproven etiology.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:A 23-year-old primiparous mother with a chronic draining breast lesion was smear-positive for acid-fast bacilli in the sputum examination after learning that her husband was a patient noncompliant to treatment.
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Key Findings & Data:Despite negative microbiological examination of the breast drainage, she was culture-positive for multidrug-resistant Mycobacterium tuberculosis complex in her sputum culture.
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Conclusion & Impact:As this case demonstrated that family screening is important for finding new patients, and tuberculous mastitis, albeit rare, should be considered in the differential diagnosis of chronic breast infections with unproven etiology.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

A 23-year-old primiparous mother with a chronic draining breast lesion was smear-positive for acid-fast bacilli in the sputum examination after learning that her husband was a patient noncompliant to treatment. Despite negative microbiological examination of the breast drainage, she was culture-positive for multidrug-resistant Mycobacterium tuberculosis complex in her sputum culture. Because she was in the lactation period, with unilateral breast involvement, and accompanying cultureproven pulmonary tuberculosis, she was accepted as secondary breast tuberculosis. After therapy with a combination of ofloxacin, cycloserin, pyrazinamid, ethambuthol and amikacin, the breast lesion healed completely. As this case demonstrated that family screening is important for finding new patients, and tuberculous mastitis, albeit rare, should be considered in the differential diagnosis of chronic breast infections with unproven etiology.

Özet

Memesindeki pürülan akıntılı kronik yara nedeniyle incelenen ilk doğumunu yeni yapmış 23 yaşındaki kadının, eşinin düzensiz tüberküloz tedavisi gördüğü öğrenildikten sonra incelenen balgamında aside dirençli bakteri pozitif bulundu. Memeden alınan akıntıdan herhangi bir etken elde edilememekle birlikte balgamından çok ilaca dirençli Mycobacterium tuberculosis kompleksi izole edildi. Hastanın laktasyon döneminde olması, tek memede tutulum olması ve birlikte mikrobiyolojik olarak doğrulanmış akciğer infeksiyonu olması nedeniyle sekonder meme tüberkülozu olarak değerlendirildi. Ofloksasin, sikloserin, pirazinamid, etambutol ve amikasin olarak düzenlenen tedavinin ardından memedeki lezyon tam olarak iyileşti. Bu olgunun gösterdiği gibi yeni hastaların saptanmasında aile taraması önemlidir ve etkeni gösterilemeyen kronik meme infeksiyonlarının ayırıcı tanısında tüberkülöz mastitin de düşünülmesi gerekir.

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Cite This Article

TÖZALGAN, Ü., KOTAN, Ş., SAYICI, Ş., ŞENGÖZ, G. (2022). A case of multidrug-resistant tuberculosis of the lung and breast due to intrafamilial transmission. Klimik Dergisi, Cilt: 24 - Sayı: 2, 119–121. https://ajindex.com/articles/573697

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