Journals / Klimik Dergisi / 2018 / Cilt: 31 - Sayı: 2

First Case of Infective Endocarditis Associated With Neisseria animaloris

Neisseria animaloris’e Bağlı İlk İnfektif Endokardit Olgusu

Pages
161–164
Publication Date
2022-10-18
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Our case is the only case of infective endocarditis that is caused by N. animaloris.

📌 3 Key Takeaways

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Objective & Hypothesis:A 25-year-old female with no remarkable medical or family history presented with sudden chest pain and shortness of breath.
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Key Findings & Data:A total of 6 blood cultures were taken, one bottle of blood culture from each arm of the patient for three consecutive days.
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Conclusion & Impact:Our case is the only case of infective endocarditis that is caused by N. animaloris.
🔬Design:Research Article
📍Scope:2013 Verileri
⚙️Variables:Domain Parameters

Abstract

A 25-year-old female with no remarkable medical or family history presented with sudden chest pain and shortness of breath. Transesophageal echocardiography revealed a defect in intraventricular septum, and a loose mass image was observed on the septal cuspis of tricuspid valve. A total of 6 blood cultures were taken, one bottle of blood culture from each arm of the patient for three consecutive days. All bottles yielded growth of Neisseria animaloris. All isolates were identified by Phoenix™ 100 (Becton Dickinson, Diagnostic Instrument System, Sparks, MD, USA), and the identification was confirmed by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) (Bruker Daltonik, Bremen, Germany). Antibiotic susceptibility results were studied by gradient diffusion method, and interpreted as resistant to penicillin G and susceptible to ceftriaxone by the European Committee on Antimicrobial Susceptibility Testing (EUCAST) 2013 standards for N. meningitidis. No risk factor such as animal contact or bite, and tooth or gum problems was detected in the patient evaluation because of the feature of the causative agent. Definitive infective endocarditis was diagnosed according to modified Duke criteria because of fever, infective endocarditis-prone cardiac condition and pulmonary embolism, vegetation in echocardiography and growth in consecutive blood cultures. Although there are some reports that N. animaloris causes wound infections in the cases bitten by a dog or a cat, there is no information about it as a causative agent for infective endocarditis. Our case is the only case of infective endocarditis that is caused by N. animaloris.

Özet

Daha öncesine ait bir hastalık öyküsü ve soygeçmişinde bir özellikolmayan 25 yaşında kadın hastanın ani gelişen göğüs ağrısıve nefes darlığı nedeniyle yapılan transtorasik ekokardiyografisindeintraventriküler septumda defekt ve triküspid kapak septalküspis üzerinde hareketli gevşek yapıda kitle imajı izlendi.Hastanın her iki kolundan birer şişe olmak üzere art arda üç günboyunca toplam 6 kan kültürü alındı. Tüm kan şişelerinde üremesaptandı. Üreyen etkenler Phoenix™ 100 (Becton Dickinson,Sparks, MD, ABD) otomatize sisteminde Neisseria animalorisolarak tanımlandı ve “matrix-assisted laser desorption ionizationtime-of-flight mass spectrometry” (MALDI-TOF MS) (BrukerDaltonik, Bremen, Almanya) ile doğrulandı. Antibiyotik duyarlılıklarıgradyan difüzyon yöntemiyle araştırıldı ve N. meningitidisiçin kabul edilen European Committee on Antimicrobial SusceptibilityTesting (EUCAST) 2013 standardlarıyla penisilin G’yedirençli, seftriaksona duyarlı olarak yorumlandı. Etkenin özelliğinedeniyle hayvan teması, hayvan ısırığı, diş veya dişeti sorunlarıaçısından sorgulanan ve değerlendirilen hastada bir risk faktörüsaptanmadı. Ateşinin, infektif endokardite eğilim yaratan kardiyakdurumunun ve akciğer embolisinin olması, ekokardiyografidevejetasyonların görülmesi ve ardışık kan kültürlerinde üremeolması nedeniyle modifiye Duke ölçütlerine göre kesin infektifendokardit tanısı konuldu. Üreyen N. animaloris’in genellikle köpekya da kedi tarafından ısırılan olgularda yara yeri infeksiyonunaneden olduğuna dair yayınlar olmasına rağmen infektif endokarditetkeni olduğuna dair bilgi yoktur. Olgumuz N. animaloris’inetken olduğu tek infektif endokardit olgusudur.

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Cite This Article

HEPER, Y., TÜZEMEN, N. Ü., ÖZAKIN, C., TUNCEL, T., HEMİŞ, R. B., YİĞİT, M., KAPSIZ, M., EFE, K., GÜLLÜLÜ, S. (2022). First Case of Infective Endocarditis Associated With Neisseria animaloris. Klimik Dergisi, Cilt: 31 - Sayı: 2, 161–164. https://ajindex.com/articles/573512

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