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Journals / KBB-Forum / 2018 / Cilt: 17 - Sayı: 3

ROLE OF SHORT-TERM ORAL CORTICOSTEROID IN PEDIATRIC SLEEP DISORDERED BREATHING AND ADENOID HYPERTROPHY ON TREATMENT OUTCOME

KISA DÖNEM ORAL KORTİKOSTEROİD KULLANIMININ PEDİATRİK UYKU BOZUKLUĞU VE ADENOİD HİPERTROFİSİNE ETKİSİ

Ayşe TÜRKMEN
Selen Güler SELEN
Ekrem Said KANKILIÇ
Sevinç BAYRAK
Ali Osman KÖKSAL
Mehtap ACAR
Journal
KBB-Forum
Pages
73–80
Publication Date
2022-10-18
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

We compared the OSA-18 survey score and adenoid sizebetween before and after treatment.Results: The total OSA-18 score and adenoid size reduced significantly after treatment (P

📌 3 Key Takeaways

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Objective & Hypothesis:Introduction and objectives: Adenoid hypertrophy and sleep disordered breathing (SDB) are generally considered common diseases ofchildhood.
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Key Findings & Data:In total, 51 children (2–11years old) were enrolled into this study.
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Conclusion & Impact:We compared the OSA-18 survey score and adenoid sizebetween before and after treatment.Results: The total OSA-18 score and adenoid size reduced significantly after treatment (P
🔬Design:Survey & Empirical Study
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Introduction and objectives: Adenoid hypertrophy and sleep disordered breathing (SDB) are generally considered common diseases ofchildhood. Oral corticosteroids have been used to treat upper airway blockages through their anti-inflammatory and lympholytic impacts.Although nasal corticosteroids are widely used in adenoid hypertrophy, there are few information about the effects of oral corticosteroids tothe adenoid tissue. We supposed that oral corticosteroid treatment may be helpful in adenoid hypertrophy due to its inflammatory relatedbackground. According to this idea we evaluated the effect of short-term oral corticosteroid treatment on adenoid hypertrophy in patientsreceiving oral corticosteroids for any other reasons.Methods: A prospective, observational study was conducted. In total, 51 children (2–11years old) were enrolled into this study. Allpatients received a 3-day course of oral corticosteroid (1 mg/kg) treatment. They were evaluated before treatment and immediately aftertreatment with the obstructive sleep apnea (OSA)-18 quality of life survey and a transnasal endoscopic examination. In addition, theevaluation of each patient included history, physical examination, and blood tests. We compared the OSA-18 survey score and adenoid sizebetween before and after treatment.Results: The total OSA-18 score and adenoid size reduced significantly after treatment (P

Özet

Giriş ve amaç: Adenoid hipertrofisi ve uyku bozukluğu olan solunum çocukluk çağının sık karşılaşılan hastalıklarındandır. Oral kortikosteroidler antiinflamatuar ve lenfolitik etkileri sayesinde üst havayolu obstrüksiyonuna yol açan hastalıklarda kullanılmaktadır. Adenoid hipertrofi tedavisinde nazal kortikosteroidler yaygın kullanılmasına rağmen oral kortikosteriodlerin adenoid dokusu üzerine olan etkileri hakkında çok az bilgi bulunmaktadır. Adenoid hipertrofisinin inflamatuar zeminle ilişkisine bağlı olarak oral kortikosteroid tedavisinin adenoid hipertrofi tedavisinde faydalı olabileceği düşüncesi ile herhangi bir nedenle oral kortikosteroid alan hastaların adenoid dokusu üzerine olan etkilerini araştırdık. Metod: Prospektif gözlemsel çalışma planlandı. Toplam 51 hasta (2 ile 11 yaş arasında) çalışmaya dahil edildi. Her hastaya (1 mg/ kg) 3 günlük oral kortikosteroid tedavisi verildi. Tedavi öncesinde ve sonrasında hastaların ailelerine obstrüktif uyku apnesi anketi (OSA-18) değerlendirmesi ve hastalara transnazal endoskopik değerlendirme yapıldı. Ayrıca her hastanın anamnezi, fizik muayenesi ve kan testleri değerlendirildi. Tedavi öncesi ve sonrasında OSA-18 anket sonuçları ve adenoid büyüklüğü karşılaştırmaları yapıldı. Sonuç: OSA-18 skorunda ve adenoid büyüklüklerinde tedavi sonrasında anlamlı azalma görüldü (p

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Cite This Article

TÜRKMEN, A., SELEN, S. G., KANKILIÇ, E. S., BAYRAK, S., KÖKSAL, A. O., ACAR, M. (2022). ROLE OF SHORT-TERM ORAL CORTICOSTEROID IN PEDIATRIC SLEEP DISORDERED BREATHING AND ADENOID HYPERTROPHY ON TREATMENT OUTCOME. KBB-Forum, Cilt: 17 - Sayı: 3, 73–80. https://ajindex.com/articles/573105

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