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Journals / Kartal Eğitim ve Araştırma Hastanesi Tıp Dergisi / 2015 / Cilt: 26 - Sayı: 1

Focal Segmental Glomerulosclerosis Secondary to Preeclampsia

Preeklampsiye Bağlı Gelişen Fokal Segmental Glomeruloskleroz

Burcu ARTUNC
Kemal SARSMAZ
Pages
94–96
Publication Date
2022-10-17
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Besides, it may lead to various complications including further exacerbation of renal pathology during pregnancy, preeclampsia, and related additional pathologies, premature birth, and intrauterine growth restriction.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Preeclampsia is a multisystemic disease characterized by hypertension and proteinuria developing after 20 weeks of gestation.
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Key Findings & Data:These changes may be reversible or permanent, causing a decrease in nephron mass.
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Conclusion & Impact:Besides, it may lead to various complications including further exacerbation of renal pathology during pregnancy, preeclampsia, and related additional pathologies, premature birth, and intrauterine growth restriction.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Preeclampsia is a multisystemic disease characterized by hypertension and proteinuria developing after 20 weeks of gestation. Preeclampsia causes some typical changes in the kidneys called preeclamptic nephropathy . These changes may be reversible or permanent, causing a decrease in nephron mass. One of the preeclamptic renal pathologies is focal segmental glomerulosclerosis. Persistence of gestational proteinuria after pregnancy has a poor renal prognosisi and it aggravates further in subsequent pregnancy potentially leading to renal insufficiency. Furthermore, presence of underlying renal pathologies or severe hypertension carry a poor antenatal prognosis. Besides, it may lead to various complications including further exacerbation of renal pathology during pregnancy, preeclampsia, and related additional pathologies, premature birth, and intrauterine growth restriction.

Özet

Preeklampsi 20. gestasyonel hafta sonrasında gelişen hipertansiyon ve proteinüri ile karakterize multisistemik bir hastalıktır. Preeklampsiye bağlı olarak preeklamptik nefropati olarak tanımlanan bazı tipik renal değişimler oluşmaktadır. Bu değişiklikler geri dönüşümlü olabileceği gibi, nefron kütlesinde azalmaya neden olan kalıcı deği- şiklikler de olabilmektedir. Preeklamptik renal patolojilerden birisi fokal segmental glomerulosklerozdur. Gebelik sırasında oluşan proteinürinin, gebelik sonrasında da devam etmesi renal prognoz açı- sından kötüdür ve bir sonraki gebelik ile daha da ağırlaşarak böbrek yetersizliğine ilerleyebilir. Ayrıca, altta yatan renal patoloji varlığı ya da şiddetli hipertansiyon antenatal prognoz açısından da oldukça kötüdür ve gebelik sırasında renal patolojinin daha da ağırlaşması, preeklampsi ve preeklampsiye bağlı ek patolojiler, erken doğum, intrauterin gelişme kısıtlılığı gibi komplikasyonlar gelişebilmektedir.

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Cite This Article

ARTUNC, B., SARSMAZ, K. (2022). Focal Segmental Glomerulosclerosis Secondary to Preeclampsia. Kartal Eğitim ve Araştırma Hastanesi Tıp Dergisi, Cilt: 26 - Sayı: 1, 94–96. https://ajindex.com/articles/571336

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