Journals / Kartal Eğitim ve Araştırma Hastanesi Tıp Dergisi / 2015 / Cilt: 26 - Sayı: 2

Advanced Corneal Injury Related to Topical Cyclopentolate Hydrochloride Addiction

Topikal Siklopentolat Hidroklorid Bağımlılığı Sonucu Gelişen İleri Düzey Korneal Hasar

Pages
179–181
Publication Date
2022-10-17
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In conclusion, cyclopentolate hydrochloride,which is frequently used in opthalmology practice, may causeaddiction similar to other anticholinergic agents, and this ad- diction may cause non-reversible visual loss.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:A 38-year-old male patient was referred to our clinic with com- plaints of a painful red eye.
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Key Findings & Data:Upon physical examination, the pa- tient was found to have bilateral visual loss secondary to cor- neal ulcers and a perforated corneal descemetocele in his lefteye.
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Conclusion & Impact:In conclusion, cyclopentolate hydrochloride,which is frequently used in opthalmology practice, may causeaddiction similar to other anticholinergic agents, and this ad- diction may cause non-reversible visual loss.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

A 38-year-old male patient was referred to our clinic with com- plaints of a painful red eye. Upon physical examination, the pa- tient was found to have bilateral visual loss secondary to cor- neal ulcers and a perforated corneal descemetocele in his lefteye. He reported having continuously used a high dose of cyclo- pentolate hydrochloride. Topical cyclopentolate hydrochlorideand benzalkonium chloride toxicity was the determined etiol- ogy. The results of the culture demonstrated simultaneous bi- lateral sterile ulcers and the history of long-term high-dose cy- clopentolate hydrochloride use. After obtaining the culture, werepaired the desmatocele with a patch graft. The culture wassterile; the corneal ulcer was related to ex tended use of high- dose topical cyclopentolate hydrochloride and benzalkoniumchloride toxcicity. According to the patient s psychiatric evalua- tion, the case was determined to be cyclopentolate hydrochlo- ride addiction. In conclusion, cyclopentolate hydrochloride,which is frequently used in opthalmology practice, may causeaddiction similar to other anticholinergic agents, and this ad- diction may cause non-reversible visual loss.

Özet

Otuz sekiz yaşında erkek hasta kliniğimize ağrı, kızarıklık şikayeti ile başvurdu. Yapılan muayenesinde her iki gözde görmekaybı, korneada ülser ve buna bağlı sol gözde perforasyonve desmatosel geliştiği görüldü. Hastanın anamnezindeuzun süreli ve yüksek doz siklopentolat hidroklorid kullanımıtespit edildi. Hastadan kültür alındıktan hemen sonra yamagrefti ile desmatosel cerrahi olarak kapatıldı. Alınan kültür- lerde üreme olmaması, ülserin steril olması, hastanın uzunsüreli ve yüksek doz siklopentolat hidroklorür kullanmasınedeniyle, korneal ülserin uzun süreli ve yüksek doz topikalsiklopentolat hidroklorür kullanımına bağlı siklopentolathidroklorür ve benzalkonyum klorür (BAC) toksisitesine bağ- lı geliştiği düşünüldü. Hastaya psikiyatri uzmanı tarafındanmadde bağımlılığı tanısı konulmasıyla bu olgu bir siklopen- tolat hidroklorür bağımlılığı olarak tanımlandı. Sonuç olarakoftalmoloji kliniklerinde uygulamada sıklıkla kullanılan topikal siklopentolat hidroklorür, diğer antikolinerjik ajanlar gibibağımlılığa neden olabilir ve bu bağımlılık geri dönüşümüolmayan görsel kayıplara neden olabilir.

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Cite This Article

GENÇ, O., KUTLUTÜRK, I., AKKAYA, C. (2022). Advanced Corneal Injury Related to Topical Cyclopentolate Hydrochloride Addiction. Kartal Eğitim ve Araştırma Hastanesi Tıp Dergisi, Cilt: 26 - Sayı: 2, 179–181. https://ajindex.com/articles/571295

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