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Journals / Kadın Doğum Dergisi / 2004 / Cilt: 2 - Sayı: 3

The effect of oral contraceptives on bone mineral density

Oral kontraseptiflerin kemik mineral dansitesi üzerine etkilerinin incelenmesi

Başak BAKSU
Ahmet VAROLAN
İnci DAVAS
Ali YAZGAN
Atıf AKYOL
Tevfik YOLDEMİR
Pages
228–231
Publication Date
2022-10-18
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

For premenopausal women, adjusted mean vertebral bone mineral density was %3.2 greater (partial f:0.009, p

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: To evalute if oral contraceptives have a protective effect against osteoporosis.
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Key Findings & Data:Materials-Methods: Total of 178 women (128 premcnopausal, 43 postmcnopausal, 7 perimenopausal), aged between 20-65, chosen randomly were recruited into study.
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Conclusion & Impact:For premenopausal women, adjusted mean vertebral bone mineral density was %3.2 greater (partial f:0.009, p
🔬Design:Survey & Empirical Study
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: To evalute if oral contraceptives have a protective effect against osteoporosis. Materials-Methods: Total of 178 women (128 premcnopausal, 43 postmcnopausal, 7 perimenopausal), aged between 20-65, chosen randomly were recruited into study. Having diseases or taking drugs with effects on bone mineral density, having one or both ovaries left behind after hysterectomy were exclusion criteria. During a questionnaire, gynecological history, life style, social activities, smoking, alcohol usage, amount of calcium taken by diet or with drugs and oral contraceptive use were assessed. Bone mineral density was measured at whole body, lumber vertebral bones, proximal femur and distal forearm. Results were analysed by multiple regression analysis. Results: Women using oral contraceptives had a %3.4 greater mean bone mineral density adjusted for body mass index and age at lumber vertebral bones (partial ^0.008, p=0.016). For premenopausal women, adjusted mean vertebral bone mineral density was %3.2 greater (partial f:0.009, p

Özet

Amaç: Oral kontraseptiflerin osteoporoza karşı koruyucu etkisi olup olmadığını araştırmak. Materyal ve Metod: Çalışmaya Şişli Etfal Eğitim ve Araştırma Hastanesi 2.Kadın Hastalıkları ve Doğum Kliniği polikliniğine Mart 1998-Mart2000 tarihleri arasında başvuran, randomize seçilen, 20-65 yaş arasında, toplam 178 hasta (128 premenopozal, 43 postmenopozal, 7 perimenopozal) alındı. Kemik kütlesini etkileyen hastalık geçirmiş veya ilaç kullanan, histerektomi sırasında bir veya iki överi korunanlar çalışma dışı bırakıldı. Anket araştırması ile jinekolojik anamnez, yaşam tarzı, sosyal aktiviteler, sigara ve alkol kullanımı, diyetle ve ek olarak alınan kalsiyum miktarı ve oral kontraseptif kullanımı sorgulandı. Kemik mineral dansitesi tüm vücut, lomber vertebra, proksimal femur ve distal ön kolda ölçüldü. Veriler çoğul regresyon yöntemi ile analiz edildi. Bulgular: Oral kontraseptif kullanan kadınlarda, vücut kütle endeksine ve yaşa göre düzeltilmiş kemik mineral dansitesi, lomber vertebra düzeyinde %3.4 daha fazla bulundu (parsiyel rJ:().OO8, p=0.016). Premenopozal kadınlarda düzeltilmiş ortalama vertebral kemik dansitesi %3.2 daha fazla iken (parsiyel r::0.009, p

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Cite This Article

BAKSU, B., VAROLAN, A., DAVAS, İ., YAZGAN, A., AKYOL, A., YOLDEMİR, T. (2022). The effect of oral contraceptives on bone mineral density. Kadın Doğum Dergisi, Cilt: 2 - Sayı: 3, 228–231. https://ajindex.com/articles/569149

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References (16)

  1. Von Werder K. Estrogen treatment for prevention and therapy of osteoporosis. Fortschr Med 1997;115(29):44-9
  2. Stevenson JC. Pathogenesis, prevention and treatment of osteoporosis. Obstet Gynecol 1990; 75 (4 Suppl):365-415, discussion 515-525
  3. Perry W, Andersson M, Mortimer C. Osteoporosis in a largely self-referred population: high prevalence but low medical priority: why? Miner Electrolyte Metab 1994;20(5):287-93
  4. Boulanger JC, Gondry J, Devoldere K. At what age should oral contraceptives be stopped? Rev Fr Gynecol Obstet 1994;89(7-9):409-13
  5. Kritz Silverstein D, Barret-Connor E. Bone mineral density in postmenopausal women as determined by prior oral contraceptive use. Am J Public Health 1993;83:100-2
  6. Murphy S, Khaw KT, Compston JE. Lack of relationship between hip and spine bone mineral density and oral contraceptive use. Eur J Clin Invest 1993;23:108-11
  7. Tuppurainen M, Kroger H, Saarikaski S, Honkanen R, Alhava E. The effects of previous oral contraceptive use on bone mineral density inperimenopausal women. Osteoporos Int 1994;4(2):93-8
  8. Volpe A, Amrom A, Cagnacci A, Battaglia C. Biochemical aspects of hormonal contraception: effects on bone metabolism. Eur J Contracept Reprod Health Care 1997;2(2): 123-6
  9. Duppe H, Gardsell P, Johnell V, Nisson BE. Bone mineral content in women: trends of change: Osteoporos Int 1992;2:262-5
  10. Gambaccians M, Spinetti A, Taponeco F, Cappagli B, Piaggesi L, Fioretti P. Longitudinal evaluation of premenopausal vertebral bone loss: Effects of a low-dose oral contraceptive preparation on bone mineral density and metabolism. Obstet Gynecol 1994;83(3):392-6
  11. Hansen MA, Overgoard K, Riss BJ, Christiansen C. Potential risk factors for development of postmenopousal osteoposis examined overa 12yearperiod. Osteoporos Int 1991;1(2):95-102
  12. Kleerekoper M, Brienza RS, Schultz LR, Johnson CC. Oral contraceptive use may protect against low bone mass. Arch Intern Med 1991;151:1971-6
  13. Lindsoy R, Tohme J, Kanders B. The effect of oral contraceptive use on vertebral bone mass in pre-and post-menopausal women. Contraception 1986;34:333-40
  14. Fortney JA, Feldblum PJ, Tolmage RV, Zhang J, Godwin JE. Bone mineral density and history of oral contraceptive use. J Reprod Med 1994;39(2):105-9
  15. Cooper C, Hannaford P, Croft P, Kay CR. Oral contraceptive pill use and fractures in women: a prospective study. Bone 1993;14(l):41-5
  16. Cromer BA, Blair JM, Mahan JD, Zibner L, Naumouski Z. A prospective comp