Journals / Journal of the Turkish-German Gynecological Association / 2005 / Cilt: 6 - Sayı: 3

Reproductive factors affecting the mammographic density in postmenopausal women

Postmenopozal kadınlarda mamografik dansiteyi etkileyen reprodüktif faktörler

Pages
223–225
Publication Date
2022-10-18
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Also higher age of menarche is positively correlated with breast density.

📌 3 Key Takeaways

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Objective & Hypothesis:Objectives: Increased breast density indicates a higher risk of breast cancer.
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Key Findings & Data:Also increased breast density impairs the detection of suspicious breast masses.
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Conclusion & Impact:Also higher age of menarche is positively correlated with breast density.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objectives: Increased breast density indicates a higher risk of breast cancer. Also increased breast density impairs the detection of suspicious breast masses. We investigated the effects of various reproductive factors on mammographic density in the postmenopausal asymptomatic women. Materials and Methods: A total of 260 women who admitted to mammography unit for screening mammograms were evaluated. Demographic and reproductive data were collected including, age, parity, age at menarche, age at menopause, total duration of lactation, maternal age at first delivery, time since menopause. Mammograms were evaluated for breast density according to Wolfe classification. Subjects were grouped according to mammographic density. Group 1 was constituted of 183 women (70.4%) who had low risk mammograms (N1 and P1). The second group included 77 (29.6%) women who had high risk mammogram. Results: The age at first delivery was not statistically different between the two groups (p=0.42). Women who had low risk mammograms were older, had higher parity, higher body mass index (BMI), lower age at menarche and higher total duration of lactation, higher age at menopause and time since menopause (p=0.01, p=0.009, p=0.03, p=0.046, p=0.01 and p=0.01, respectively). Parity and BMI negatively affect mammographic density (coefficient; -0.173 and -0.158, respectively), however, increasing age at menarche positively correlated with mammographic density (coefficient; 0.142). Conclusion: Although obesity is a well-known risk factor for breast cancer, higher body mass index was found as inversely correlated with mammographic breast density with parity. Also higher age of menarche is positively correlated with breast density.

Özet

Amaç: Artmış meme dansitesi meme kanseri riskini arttırdığı gibi kuşkulu meme kitlesi tanısını da güçleştirmektedir. Bu çalışmada, asemptomatik postmenopozal kadınlarda çeşitli reprodüktif faktörlerin meme dansitesi üzerine olan etkilerini araştırdık. Materyal ve Metot: Tarama mamografisi için başvuran toplam 260 hasta çalışma kapsamında değerlendirildi. Olgulara ait yaş, parite, menarfl yaşı, menopoz yaşı, menopozu takiben geçen süre, toplam laktasyon süresi ve ilk doğum yaşı ve vücut kitle indeksi (VKİ) gibi demografik ve reprodüktif faktörlere ilişikin veriler toplandı. Mamografik meme dansitesi Wolfe sınıflamasına göre değerlendirildi. Olgular mamografik dansitelerine göre iki gruba ayrıldı. Grup 1 düflük riskli mamografileri (N1 ve P1) olan 183 kifliden (%70.4), grup 2 ise yüksek riskli mamografileri olan 77 kifliden (%29.6) oluşturuldu. Sonuçlar: İki grup arasında ilk doğum yaşı açısından fark yoktu (p=0.42). Düşük riskli mamografileri olan kadınlar daha ileri yaş ve daha fazla parite, daha yüksek VKİ, daha erken menarfl, daha fazla laktasyon süresi, daha geç menopoz yaşı ve daha uzun menopoz süresine sahiptiler (sırasıyla, p=0.01, p=0.009, p=0.03, p=0.046, p=0.01 and p=0.01). Değerlendirilen faktörlerden parite ve VKİ mamografik dansiteyi negatif olarak etkilerken (korelasyon katsayısı sırasıyla, -0.173 ve -0.158), menarş yaşı ile mamografik dansite arasında pozitif ilişki bulundu (korelasyon katsayısı, 0.142). Tartışma: Artmış vücut kitlesi meme kanseri için bilinen bir risk faktörü olmasına rağmen, meme dansitesi ile arasında parite ile beraber negatif korelasyon vardır. Öte yandan artan menarfl yaşı Mamografik dansite arasında pozitif bir ilişki bulundu.

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Cite This Article

DİLEK, B., GÜLHAN, S., BARCA, N., DİLEK, S. (2022). Reproductive factors affecting the mammographic density in postmenopausal women. Journal of the Turkish-German Gynecological Association, Cilt: 6 - Sayı: 3, 223–225. https://ajindex.com/articles/568041

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