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Journals / Journal of the Turkish-German Gynecological Association / 2009 / Cilt: 10 - Sayı: 1

Erken gebelikte istenmeden meydana gelen uzun etkili gonadotropin salgılattırıcı hormon agonisti maruziyeti sonucu oluşan aşırı gerilmiş dublike mesane ve ani fetal ölüm

Overdistended duplicated bladder and sudden fetal demise after inadverdent exposure to long-acting gonadotropin-releasing hormone agonist in early pregnancy

Nupur GUPTA
Suneeta MITTAL
Shikha SARANGI
Deepika DEKA
Pages
55–56
Publication Date
2022-10-18
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Till date, no consensus has been gathered on the management of gonadotropin-releasing hormone agonist exposed pregnancies, risk of teratogenecity and perinatal outcome.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Gonadotropin-releasing hormone agonists are being increasingly used in infertility and gynaecological practice for treatment of fibroids, endometriosis and in vitro fertilization cycles.
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Key Findings & Data:A 24-year-old nulliparous lady with a fibroid uterus had an inadvertent exposure to two doses of leuprolide acetate and conceived spontaneously while awaiting hysteroscopic myomectomy.
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Conclusion & Impact:Till date, no consensus has been gathered on the management of gonadotropin-releasing hormone agonist exposed pregnancies, risk of teratogenecity and perinatal outcome.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Gonadotropin-releasing hormone agonists are being increasingly used in infertility and gynaecological practice for treatment of fibroids, endometriosis and in vitro fertilization cycles. A 24-year-old nulliparous lady with a fibroid uterus had an inadvertent exposure to two doses of leuprolide acetate and conceived spontaneously while awaiting hysteroscopic myomectomy. The fetus suffered anomalies of urogenital system and sudden intrauterine fetal demise at 31 weeks gestation. Till date, no consensus has been gathered on the management of gonadotropin-releasing hormone agonist exposed pregnancies, risk of teratogenecity and perinatal outcome.

Özet

Gonadotropin salınım hormon agonistlerinin infertilitede ve fibroidlerin, endometriozisin tedavisindeki jinekolojik uygulamada ve in vitro fertilizasyonda kullanımı artmaktadır. 24 yaşında fibroid uterusu olan nullipar bayan istemeyerek 2 doz leuprolide acetate’a maruz kaldı ve histeroskopik miyomektomi planlanırken spontan olarak gebe kaldı. Fetuste ürogenital system anomalileri görüldü ve 31. gebelik haftasında ani intrauterin fetal ölüm görüldü. Bu tarihe kadar, gebelerde gonadotropin salınım hormon agonistinin kullanımının teratonejite riski ve perinatal dönem üzerine etkisi konusunda fikir birliği ortaya konulmamıştır.

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Cite This Article

GUPTA, N., MITTAL, S., SARANGI, S., DEKA, D. (2022). Erken gebelikte istenmeden meydana gelen uzun etkili gonadotropin salgılattırıcı hormon agonisti maruziyeti sonucu oluşan aşırı gerilmiş dublike mesane ve ani fetal ölüm. Journal of the Turkish-German Gynecological Association, Cilt: 10 - Sayı: 1, 55–56. https://ajindex.com/articles/567857

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References (4)

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