Journals / Journal of the Turkish-German Gynecological Association / 2012 / Cilt: 13 - Sayı: 1

Klinik ve laboratuvar özellikler hemoliz, artmış karaciğer enzimleri ve düşük trombosit sayımı sendromlu gebelerde maternal ve fetal sonuçları etkiler mi?

Do clinical and laboratory parameters effect maternal and fetal outcomes in pregnancies complicated with hemolysis, elevated liver enzymes, and low platelet count syndrome?

Pages
1–7
Publication Date
2022-10-18
DOI
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⚡ TL;DR(Too Long; Didn't Read)

Conclusion: Neither clinical characteristics nor laboratory parameters was found effective for prediction of adverse maternal and fetal outcomes. (J Turkish-German Gynecol Assoc 2012; 13: 1-7)

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: The aim of the study was to investigate whether the clinical features and laboratory parameters affect maternal and fetal outcomes in pregnancies complicated with HELLP syndrome.
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Key Findings & Data:Material and Methods: The medical records of pregnant patients complicated with HELLP syndrome were analyzed retrospectively between June 01, 2003 and June 01, 2010.
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Conclusion & Impact:Conclusion: Neither clinical characteristics nor laboratory parameters was found effective for prediction of adverse maternal and fetal outcomes. (J Turkish-German Gynecol Assoc 2012; 13: 1-7)
🔬Design:Research Article
📍Scope:2003 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: The aim of the study was to investigate whether the clinical features and laboratory parameters affect maternal and fetal outcomes in pregnancies complicated with HELLP syndrome. Material and Methods: The medical records of pregnant patients complicated with HELLP syndrome were analyzed retrospectively between June 01, 2003 and June 01, 2010. The demographic data, medical history, admission symptoms, clinical and laboratory findings and recovery time were evaluated. The adverse maternal outcomes including eclampsia, placental abruption, disseminated intravascular coagulation, postpartum hemorrhage, pulmonary complications, cerebral edema and visual loss were recorded. Fetal growth restriction, necessity for neonatal intensive care unit admission and perinatal mortality were recorded as an adverse fetal outcome. Results: The incidence of HELLP syndrome was 0.52%. The mean age of the patients was 28.93±7.90 (range 17-45). HELLP syndrome was diagnosed on average in the 33.68±4.41th (ranged 24-40) week of gestation. Eighteen cases (40.9%) were nullipara and twenty-six cases (59.1%) multipara. The most common complications were eclampsia (40.9%) and abruption placenta (15.9%). Pregnancy was terminated within 48 hours in all patients. The rate of cesarean section was 90.9%. Perinatal mortality rate in HELLP syndrome was 31.8%. There was no maternal mortality. Conclusion: Neither clinical characteristics nor laboratory parameters was found effective for prediction of adverse maternal and fetal outcomes. (J Turkish-German Gynecol Assoc 2012; 13: 1-7)

Özet

Amaç: Çalışmanın amacı HELLP sendromlu gebelerde klinik özellikler ile laboratuvar belirteçlerinin maternal ve fetal sonuçları etkileyip etkilemediğini araştırmaktır. Gereç ve Yöntemler: 01 Haziran 2003 ile 01 Haziran 2010 tarihleri arasında HELLP sendromlu gebe kadınların tıbbi kayıtları geriye dönük olarak incelendi. Demografik verileri, tıbbi öyküsü, başvuru yakınmaları, klinik ve laboratuvar bulguları ve iyileşme süreleri değerlendirildi. Eklampsi, plasenta dekolmanı, yaygın damar içi pıhtılaşma, postpartum kanama, akciğer komplikasyonları, beyin ödemi ve görme kaybını içeren olumsuz maternal sonuçlar kaydedildi. Fetal büyüme kısıtlılığı, yenidoğanın yoğun bakıma kabulü, perinatal mortalite olumsuz fetal sonuçlar olarak kaydedildi. Bulgular: HELLP sendromu insidansı %0.52, olguların ortalama yaşı 28.93±7.90 (aralık 17-45) idi. HELLP sendromu gebeliğin ortalama 33.68±4.41 (aralık 24-40) haftasında tanındı. 18 olgu nullipar (%40.9), 26 olgu (%59.1) multipar idi. En sık komplikasyon eklampsi (%40.9) ve ablasyo plasenta (%15.9) oldu. Tüm hastalarda gebelik 48 saat içerisinde sonlandırıldı. Sezaryen hızı %90.9, perinatal mortalite %31.8 idi. Hiç maternal mortalite görülmedi. Sonuç: Ne klinik özellikler ne de laboratuvar belirteçler olumsuz maternal ve perinatal sonuçları öngörmede etkili bulunmadı. (J Turkish-German Gynecol Assoc 2012; 13: 1-7)

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Cite This Article

BEZİRCİOĞLU, İ., BALOĞLU, A., ÇETİNKAYA, B., PİRİM, B. (2022). Klinik ve laboratuvar özellikler hemoliz, artmış karaciğer enzimleri ve düşük trombosit sayımı sendromlu gebelerde maternal ve fetal sonuçları etkiler mi?. Journal of the Turkish-German Gynecological Association, Cilt: 13 - Sayı: 1, 1–7. https://ajindex.com/articles/567687

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