Journals / Journal of Neurological Sciences (Turkish) / 2008 / Cilt: 25 - Sayı: 2

The differential diagnosis of multiple sclerosis

Multiple sklerozda ayırıcı tanı

Pages
171–184
Publication Date
2022-10-19
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this review, relapsing-remitting MS, progressive MS, variants of MS and white matter lesions on MRI that can resemble MS were discussed in order to make the differential diagnosis of MS.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:In some cases, the diagnosis and the differential diagnosis of multiple sclerosis (MS) are difficult.
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Key Findings & Data:Because no specific test for MS is available, the diagnosis of MS is based on evidence from the history, neurological findings, MRI, CSF examination and evoked potentials.
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Conclusion & Impact:In this review, relapsing-remitting MS, progressive MS, variants of MS and white matter lesions on MRI that can resemble MS were discussed in order to make the differential diagnosis of MS.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

In some cases, the diagnosis and the differential diagnosis of multiple sclerosis (MS) are difficult. Because no specific test for MS is available, the diagnosis of MS is based on evidence from the history, neurological findings, MRI, CSF examination and evoked potentials. These diagnostic tests are not specific and sensitive to MS. On the other hand, since MRI is being used intensively in neurological practice nowadays, some white matter abnormalities seen on MRI that mimic MS make confusion in diagnosis. In this review, relapsing-remitting MS, progressive MS, variants of MS and white matter lesions on MRI that can resemble MS were discussed in order to make the differential diagnosis of MS.

Özet

Klinik pratiğinde, multiple skleroz (MS) tanısında zorluklar yaşanır. Tanıda klinik bulgular yanında, MRG'de lezyon özellikleri, lezyonların zamansal ve uzaysal dağılımı, beyin-omurilik sıvısı incelemesi, uyarılmış potansiyeller gibi yardımcı tanısal incelemelere gereksinim duyulur. Ancak bu testlerin tanısal duyarlılık ve özgüllüğü sınırlıdır. Ayrıca günümüzde çok sık kullanılan MRG ile de tanısal kafa karışıklığı yaşanmaktadır. Örneğin MRG'de rastlantısal olarak görülen bir ya da birkaç densite değişikliğinin MS'den ayrılması ve tanınması çoğu zaman zorluklar içermektedir. MS'in klinik ve laboratuar bulgularının birçok hastalıkta da görülmesi nedeniyle, ayırıcı tanıda çok sayıda hastalık ele alınmalıdır. Bu amaçla, bu derlemede, relapsing-remitting MS, progresif MS ve MS varyantlarını taklit eden klinik sendromlar ve MRG'de görülen hiperintensiteler ayırıcı tanıda irdelenmiştir.

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Cite This Article

KARATAŞ, M. (2022). The differential diagnosis of multiple sclerosis. Journal of Neurological Sciences (Turkish), Cilt: 25 - Sayı: 2, 171–184. https://ajindex.com/articles/565553

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