Objects: Different theories were suggested on the etiopathogenesis of transient global amnesia.Methods: We demonstrate a patient with transient global amnesia, in whom, a transient hyperintense signal change on left hippocampus was detected in diffusion- and T2- weighted magnetic resonance images.Conclusion: The absence of vascular risk factors or atherosclerotic changes in neuroimaging, in addition to transient lesion and antecedent migraine attack suggest the phenomenon of “spreading depression” secondary to migraine as underlying etiopathogenetic mechanism of transient global amnesia in this patient.
📌 3 Key Takeaways
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Objective & Hypothesis:Objects: Different theories were suggested on the etiopathogenesis of transient global amnesia.Methods: We demonstrate a patient with transient global amnesia, in whom, a transient hyperintense signal change on left hippocampus was detected in diffusion- and T2- weighted magnetic resonance images.Conclusion: The absence of vascular risk factors or atherosclerotic changes in neuroimaging, in addition to transient lesion and antecedent migraine attack suggest the phenomenon of “spreading depression” secondary to migraine as underlying etiopathogenetic mechanism of transient global amnesia in this patient.
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Key Findings & Data:Objects: Different theories were suggested on the etiopathogenesis of transient global amnesia.Methods: We demonstrate a patient with transient global amnesia, in whom, a transient hyperintense signal change on left hippocampus was detected in diffusion- and T2- weighted magnetic resonance images.Conclusion: The absence of vascular risk factors or atherosclerotic changes in neuroimaging, in addition to transient lesion and antecedent migraine attack suggest the phenomenon of “spreading depression” secondary to migraine as underlying etiopathogenetic mechanism of transient global amnesia in this patient.
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Conclusion & Impact:Objects: Different theories were suggested on the etiopathogenesis of transient global amnesia.Methods: We demonstrate a patient with transient global amnesia, in whom, a transient hyperintense signal change on left hippocampus was detected in diffusion- and T2- weighted magnetic resonance images.Conclusion: The absence of vascular risk factors or atherosclerotic changes in neuroimaging, in addition to transient lesion and antecedent migraine attack suggest the phenomenon of “spreading depression” secondary to migraine as underlying etiopathogenetic mechanism of transient global amnesia in this patient.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters
Abstract
Objects: Different theories were suggested on the etiopathogenesis of transient global amnesia.Methods: We demonstrate a patient with transient global amnesia, in whom, a transient hyperintense signal change on left hippocampus was detected in diffusion- and T2- weighted magnetic resonance images.Conclusion: The absence of vascular risk factors or atherosclerotic changes in neuroimaging, in addition to transient lesion and antecedent migraine attack suggest the phenomenon of “spreading depression” secondary to migraine as underlying etiopathogenetic mechanism of transient global amnesia in this patient.
Özet
Giriş: Geçici global amnezinin etiyo-patogenezinde pek çok farklı hipotezler öne sürülmüştür.Metot: Bu yazıda, difüzyon ve T2 ağırlıklı kraniyal MRI incelemesinde sol hipokampusta geçici hiperintensite saptanan bir geçici global amnezi olgusu sunulmaktadır.Sonuç: Hastada vasküler risk faktörlerinin olmaması, nöro-görüntülemede aterosklerotik değişikliklerin görülmemesi, ve geçici lezyon öncesinde migren atağının olması bu hastada geçici global amnezinin etiyo-patogenetik mekanizması olarak migrene sekonder gelişen “spreading depression” teorisini desteklemektedir.
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Cite This Article
SELÇUK, H., BENBİR, G., ERTAN, S., KARA, B., ALBAYRAM, S., ERTAN, T. (2022). Geçici global amnezide difüzyon-ağırlıklı MRI'da geçici hiperintensite. Journal of Neurological Sciences (Turkish), Cilt: 26 - Sayı: 2, 227–231. https://ajindex.com/articles/565540
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