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Journals / Journal of Neurological Sciences (Turkish) / 2009 / Cilt: 26 - Sayı: 3

Lambert-eaton myastenik sendromunun eşlik ettiği subakut serebellar dejenerasyon vakası

A case of subacute cerebellar degeneration coexisting with lambert-eaton myastenic syndrome

Münevver CELİK
Dilek NECİOĞLU ORKEN
Semra ACAR
Gulay KENANGİL
Pages
371–375
Publication Date
2022-10-19
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

We present here a case with symptoms of subacute cerebellar degeneration coexisting with LEMS.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Paraneoplastic cerebellar degeneration (PCD) is a neurological disorder characterized by the subacute onset of cerebellar dysfunction, sometimes with dysarthria, dysphagia, nystagmus, mental changes, muscular and sensory deficits.
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Key Findings & Data:Cancers of the lung, ovary, breast and lymphoma are the most frequent causal neoplasms.
💡
Conclusion & Impact:We present here a case with symptoms of subacute cerebellar degeneration coexisting with LEMS.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Paraneoplastic cerebellar degeneration (PCD) is a neurological disorder characterized by the subacute onset of cerebellar dysfunction, sometimes with dysarthria, dysphagia, nystagmus, mental changes, muscular and sensory deficits. Cancers of the lung, ovary, breast and lymphoma are the most frequent causal neoplasms. Furthermore, PCD may occur in association with the Lambert- Eaton myasthenic syndrome (LEMS). LEMS is a rare syndrome with fluctuating muscle weakness, hyporeflexia and autonomic dysfunction, predominantly effecting men. We present here a case with symptoms of subacute cerebellar degeneration coexisting with LEMS.

Özet

Paraneoplastik serebellar dejenerasyon (PSD), subakut serebellar bozukluğa eşlik eden dizartri, disfaji, nistagmus, mental değişiklikler, parezi ve duysal defisitlerle karakterize bir nörolojik bozukluktur. En sık akciğer, over, meme kanserleri ve lenfomalarla birliktelik gösterir. Ayrıca Lambert-Eaton myastenik sendromu (LEMS) ile de birlikteliği bilinmektedir. LEMS dalgalanan kas güçsüzlüğü, hiporefleksi ve otonomik bozukluklarla giden ve en fazla erkekleri etkileyen nadir görülen bir sendromdur. Bu makalede, subakut serebellar dejenerasyon bulguları ile birliktelik gösteren bir LEMS vakası sunulmuştur.

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Cite This Article

CELİK, M., ORKEN, D. N., ACAR, S., KENANGİL, G. (2022). Lambert-eaton myastenik sendromunun eşlik ettiği subakut serebellar dejenerasyon vakası. Journal of Neurological Sciences (Turkish), Cilt: 26 - Sayı: 3, 371–375. https://ajindex.com/articles/565489

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