Journals / Journal of Neurological Sciences (Turkish) / 2009 / Cilt: 26 - Sayı: 1

Unilateral ağrılı paravertebral kas spasmında botulinum toksin A tedavisi: Olgu sunumu

Botulinum toxin A treatment in unilateral painful paravertebral muscle spasm: Case report

Pages
92–96
Publication Date
2022-10-19
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The reduction of pain before the disappearance of the muscle spasm suggests that BTX-A is effective in the treatment of chronic pain refractory to the other therapeutic options.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Botulinum toxin A (BTX-A) has been used in the treatment of chronic pain since effective pain relief was experienced by sufferers of spasticity and dystonia.
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Key Findings & Data:Our patient had developed disciitis after the operation of lumbar disc herniation (L4-L5) and resultant muscle spasm had been observed 20 days after the operation.
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Conclusion & Impact:The reduction of pain before the disappearance of the muscle spasm suggests that BTX-A is effective in the treatment of chronic pain refractory to the other therapeutic options.
🔬Design:Survey & Empirical Study
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Botulinum toxin A (BTX-A) has been used in the treatment of chronic pain since effective pain relief was experienced by sufferers of spasticity and dystonia. In our study we aim to discuss the effectiveness of BTX-A in the treatment of the chronic pain that was refractory to traditional therapeutic options. Our patient had developed disciitis after the operation of lumbar disc herniation (L4-L5) and resultant muscle spasm had been observed 20 days after the operation. He complained of severe back pain with a Visual Analog Scale score of 100 millimeter and Oswestry Low Back Pain Questionnaire score of 50. Intravenous antibiotherapy, analgesics and anti-inflammatory medication, and hyperbaric oxygen treatment were applied, and upon persistence of the complaints BTX-A treatment was planned for univertebral muscle spasm and resultant pain. A total of 140 units of BTX-A (Botox) accompanied by EMG was injected due to the muscle spasm severity, between thoracal 1 and lumbar 5 vertebras where paravertebral muscle spasm was observed. The patient was visited at 1,2,3,4 weeks and at 2, 4, and 6 months. Pain disappeared at the end of the second week while the paravertebral muscle spasm improved at the end of the third week. Patient's complaints did not recur and he was noted to maintain his daily activities. The reduction of pain before the disappearance of the muscle spasm suggests that BTX-A is effective in the treatment of chronic pain refractory to the other therapeutic options.

Özet

Spastisite ve distonisi olanlarda ağrının etkili bir şekilde azaldığı gözlendiğinden beri Botulinum Toksin –A (BTX-A) kronik ağrı tedavisinde kullanılmaktadır. Çalışmamızda diğer bilinen tedavi seçeneklerine yanıtsız kronik ağrı tedavisinde BTX-A'nın etkisini tartışmayı amaçladık. L4-L5 lomber disk hernisi operasyonundan 20 gün sonra diskitis ve kas spasmı gelişen, vizüel ağrı skalası 100mm ve Oswestry ağrı sorgulama skoru 50 olan olgumuz şiddetli sırt ağrısından yakınmaktaydı. İntravenöz antibiyoterapi, analjezik ve antiinflamatuar tedavi ile hiperbarik oksijen tedavisi uygulanan hastada şikayetlerinin devam etmesi üzerine univertebral kas spasmı ve ağrı için BTX-A tedavisi planlandı. EMG eşliğinde 1.torakal ve 5.lomber vertebralar arasında, paravertebral kas spasmı saptanan bölgelere kas spasmının şiddetine gore toplam 140 ünite BTX-A (Botox) enjekte edildi. Olgu 1.,2.,3.,4. haftalarda ve 2.,4. ve 6. aylarda muayene edildi. İkinci haftanın sonunda ağrı kaybolurken paravertebral kas spasmı 3. haftanın sonunda düzeldi. Olgunun şikayetleri tekrarlamamış olup günlük akivitelerini sürdürebilmekteydi. Ağrının kas spasmı kaybolmadan daha once düzelmesi BTX-A'nın diğer tedavi seçeneklerine yanıtsız kronik ağrı tedavisinde etkili olduğunu düşündürmektedir.

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Cite This Article

SARAÇOĞLU, M., AŞIR, A., BOYLU, E., DOMAÇ, F. M. (2022). Unilateral ağrılı paravertebral kas spasmında botulinum toksin A tedavisi: Olgu sunumu. Journal of Neurological Sciences (Turkish), Cilt: 26 - Sayı: 1, 92–96. https://ajindex.com/articles/565462

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References (15)

  1. Abbott JA, Jarvis SK, Lyons SD, Thomson A, Vancaille TG. Botulinum toxin type A for chronic pain and pelvic floor spasm in women: a randomized controlled trial. Obstet Gynecol. 2006; 108(4):915-23
  2. Aoki KR. Evidence for antinociceptive activity of botulinum toxin type A in pain management. Headache 2003; 43: 9-15
  3. Benecke R, Dressler D, Kunesch E, Probst T. Use of botulinum toxin in the treatment of muscle pain. Schmerz 2003; 17 (6): 450-8 (abstract)
  4. Chalkiadi A, Rohr UP, Hefter H. Early pain reduction in the treatment of spasticity after a single injection of botulinum a toxin. Dtsch Med Wochenschr 2001; 126 (48):1361-4 (abstract)
  5. Difazio M, Jabbari B. A focused review of the use of botulinum toxins for low back pain. Clin J Pain. 2002;18 (6):155-62
  6. Ferreira JJ, Couto M, Costa J et al. Botulinum toxin for the treatment of pain syndromes. Acta Reumatol Port. 2006;31(1):49-62 (abstract)
  7. Foster L, Clapp L, Erickson M, Jabbari B. Botulinum toxin A and chronic low back pain: a randomized, double- blind study. Neurology 2001; 56 (10):1290-3
  8. Freund BJ, Schwartz M. Treatment of whiplash associated neck pain with botulinum toxin-A: a pilot study. J Rheumatol. 2001: 27 (2): 481-484. comment in J Rheumatol. 2001; 28 (7): 1740
  9. Gallien P, Nicolas B, Petrilli S,et al. Role for botulinum toxin in back pain treatment in adults with cerebral palsy: report of a case. Joint Bone Spine 2004;71(1):76-8
  10. Jabbari B, Ney J, Sichani A, et al. Treatment of refractory, chronic low back pain with botulinum neurotoxin A: an open-label, pilot study. Pain Med 2006; 7(3):260-4
  11. Jankovic J. Botulinum toxin therapy for cervical dystonia. Neurotox Research. 2006;9(2-3):145-8
  12. Juan FJ. Use of botulinum toxin-A for musculoskeletal pain in patients with whiplash associated disorders. BMC Musculoskelet Disord 2004; 5(1):5
  13. Ney JP, Difazio M, Sichiani A,et al. Treatment of chronic low back pain with successive injections of botulinum toxin A over 6 months: a prospective trial of 60 patients. Clin J Pain 2006;22(4):363-9
  14. Sheean G. Botulinum toxin for the treatment of musculoskeletal pain and spasm. Curr Pain Headache Rep 2002;6 (6): 460-9
  15. Truong DD, Jost WH. Botulinum toxin: clinical use. Parkinsonism Relat Disord 2006;12(6):331-55.