Journals / Journal of Neurological Sciences (Turkish) / 2011 / Cilt: 28 - Sayı: 1

Duyusal sinir ileti çalışmalarında yeni bir bileşik parametrenin kullanımı: Duyusal sinir aksiyon potansiyelinde amplitüd/ yükselme zamanı

The utility of a novel composite parameter in sensory nerve conduction studies: Amplitude/ rise time of sensory nerve action potential

Pages
14–27
Publication Date
2022-10-19
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusions: Evaluation of SU-A/RT as an additional parameter would increase the diagnostic utility of NCS in detecting DSSP.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: To evaluate the new composite parameter (i.e., the ratio of amplitude to rise time) of sensory nerve action potential in patients with diabetic distal symmetric sensory polyneuropathy (DSSP).
📊
Key Findings & Data:Methods: 82 diabetic patients (two subgroups of normal and deteriorated NCS) and 34 controls were evaluated based on nerve conduction studies (NCS), rise time and the ratio of amplitude to rise time (A/RT).
💡
Conclusion & Impact:Conclusions: Evaluation of SU-A/RT as an additional parameter would increase the diagnostic utility of NCS in detecting DSSP.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: To evaluate the new composite parameter (i.e., the ratio of amplitude to rise time) of sensory nerve action potential in patients with diabetic distal symmetric sensory polyneuropathy (DSSP). Methods: 82 diabetic patients (two subgroups of normal and deteriorated NCS) and 34 controls were evaluated based on nerve conduction studies (NCS), rise time and the ratio of amplitude to rise time (A/RT). Results: The A/RT (cut off value = 1) of medial plantar, sural (SU) and superficial peroneal nerves were quite informative in each group (P < 0.0001, for relevant nerves). However, SU- A/RT was more reliable and useful than other nerves based on specifity and predictive values. Conclusions: Evaluation of SU-A/RT as an additional parameter would increase the diagnostic utility of NCS in detecting DSSP.

Özet

Amaç: Diyabetik distal simetrik duyusal polinöropatili (DSDP) hastalarda duyusal sinir aksiyon potansiyelini yeni bileşik bir parametre ( amplitüdün yükselme zamanına oranı) ile değerlendirmek. Materyal ve Metod: 82 diyabetik hasta (elektrofizyolojik olarak normal ve hasarlı olarak iki alt grup) ve 34 kontrol sinir iletim çalışmaları (SİÇ), yükselme zamanı ve amplitüdün yükselme zamanına oranı (A/YZ) ile değerlendirildi. Sonuçlar: Medial plantar, sural (SU) ve yüzeyel peroneal sinirler için A/YZ ( ayrım değeri = 1) her iki hasta grubu için de oldukça bilgi vericiydi (P < 0.0001, sözü edilen sinirler için). Bununla beraber, özgüllük ve öngörüsel değerler göz önüne alındıklarında SU- A/YZ diğer sinirlere göre daha güvenilir ve kullanışlıydı. Yorumlar: SU-A/YZ in ek bir parametre olarak değerlendirilmesi DSDP' nin araştırılmasında SİÇ nın tanısal kullanılabilirliğini artıracaktır.

🔖

Cite This Article

ULUÇ, K., SUNTER, G., ISAK, B., SUN, A., TANRIDAĞ, T. (2022). Duyusal sinir ileti çalışmalarında yeni bir bileşik parametrenin kullanımı: Duyusal sinir aksiyon potansiyelinde amplitüd/ yükselme zamanı. Journal of Neurological Sciences (Turkish), Cilt: 28 - Sayı: 1, 14–27. https://ajindex.com/articles/565369

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (15)

  1. Bolton CF. Mononeuropathies of the lower extremities, In: Clinical electromyogroupaphy. Ed's, Brown WF and Bolton CF, Butterworth's, Boston, MA, ed1, 1987, pp. 526–527. (1
  2. Dyck PJ, Karnes J, O'Brien PC, Swanson CJ. Neuropathy Symptom Profile in health, motor neuron disease, diabetic neuropathy, and amyloidosis. Neurology, 1986;36:1300-1308
  3. Herrmann DN, Ferguson ML, Pannoni V, Barbano RL, Stanton M, Logigian EL. Plantar nerve AP and skin biopsy in sensory neuropathies with normal routine conduction studies. Neurology, 2004;63:879-885(2
  4. Johnson EW. Dorsal sural nerve. In: Practical Electromyogroupaphy. Ed's, Johnson EW and Pease WS, Williams & Wilkins, Baltimore, ed 3, 1997, pp. 191–193. (3
  5. Killian JM, Foreman PJ. Clinical utility of dorsal sural nerve conduction studies. Muscle Nerve, 2001; 24: 817-820. (4
  6. Lacomis D. Small-fiber neuropathy. Review Muscle Nerve. 2002; 26(2):173-188. (5
  7. Lo YL, Xu LQ, Leoh TH, Dan YF, Tan YE, Nurjannah S, et al. Superficial peroneal sensory and sural nerve conduction studies in peripheral neuropathy. J. Clin. Neurosci., 2006;13:547-549. (6
  8. Løseth S, Nebuchennykh M, Stålberg E, Mellgroupen SI. Medial plantar nerve conduction studies in healthy controls and diabetics. Clin Neurophysiol 2007;118: 1155-1161. (7
  9. Marinou K, Tousoulis D, Antonopoulos AS, Stefanadi E, Stefanadis C. Obesity and cardiovascular disease: from pathophysiology to risk stratification. Int J Cardiol 2010; 138: 3-8. (8
  10. Pfeifer SM, Kives S. Polycystic ovary syndrome in the adolescent. Obstet Gynecol Clin North Am. 2009; 36:129-152(9
  11. Park KS, Lee SH, Lee KW, Oh SJ. Interdigital nerve conduction study of the foot for an early detection of diabetic sensory polyneuropathy. Clin. Neurophysiol., 2003;114:894-897(10
  12. Suarez GA, Opfer-Gehrking TL, Offord KP, Atkinson EJ, O'Brien PC, Low PA. The Autonomic Symptom Profile: a new instrument to assess autonomic symptoms. Neurology,1999;52:523-528
  13. Tamura N, Kuwabara S, Misawa S, Mori M, Nakata M, Hattori T. Superficial radial sensory nerve potentials in immune-mediated and diabetic neuropathies. Clin. Neurophysiol., 2005;116:2330- 2333(11
  14. Uluc K, Isak B, Borucu D, Temucin CM, Cetinkaya Y, Koytak PK, et al. Medial plantar and dorsal sural nerve conduction studies increase the sensitivity in the detection of neuropathy in diabetic patients. Clin. Neurophysiol., 2008;119:880-885. (12
  15. Zochodne DW. Diabetic polyneuropathy: an update. Curr. Opin. Neurol., 2008;21: 52