Journals / Cukurova Medical Journal / 2018 / Cilt: 43 Sayı: Ek 1

Long term results of total parathyroidectomy/autotransplantation without cryopreservation in secondary hyperparathyroidism

Sekonder hiperparatiroidizm olgularında kriyoprezervasyonsuz total paratiroidektomi/önkol ototransplantasyon tekniğinin uzun dönem sonuçları

Pages
129–138
Publication Date
2018-12-29
DOI
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Conclusion: In patients with end stage renal failure and secondary HPT, bilateral cervical thymectomy concurrent with total parathyroidectomy/auto transplantation without cryopreservation can be applied as a safe and efficient surgical procedure.

📌 3 Key Takeaways

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Objective & Hypothesis:Purpose: The aim of this study was to compare the efficacy and early-late results of subtotal parathyroidectomy and total parathyroidectomy/auto transplantation without cryopreservation conducted on cases with secondary hyperparathyroidism (HPT).
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Key Findings & Data:Materials and Methods: 68 patients with secondary HPT who had parathyroidectomy were analysed retrospectively.
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Conclusion & Impact:Conclusion: In patients with end stage renal failure and secondary HPT, bilateral cervical thymectomy concurrent with total parathyroidectomy/auto transplantation without cryopreservation can be applied as a safe and efficient surgical procedure.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Sekonder hiperparatiroidi · total paratiroidektomi · ototransplantasyon

Abstract

Purpose: The aim of this study was to compare the efficacy and early-late results of subtotal parathyroidectomy and total parathyroidectomy/auto transplantation without cryopreservation conducted on cases with secondary hyperparathyroidism (HPT). Materials and Methods: 68 patients with secondary HPT who had parathyroidectomy were analysed retrospectively. In group1 (n=47) subtotal parathyroidectomy, in group2 (n=21) total parathyroidectomy/auto transplantation without cryopreservation were performed in our clinic. Patients' demographic characteristics and clinical features were evaluated. Results: In group1 8 patients (14.9%), in group2 17 patients (76.2%) had concurrent thymectomies. The rates of persistant HPT in group1 and group2 were 14.9% (n=7), 4.8% (n=1) respectively. In group2 no recurrent HPT was seen, in group2 10.6% (n=5) of the patients had recurrent HPT. The reasons of persistent and recurrent HPT were ectopic or supernumerary glands in 69.2% (n=9) of the patients. Conclusion: In patients with end stage renal failure and secondary HPT, bilateral cervical thymectomy concurrent with total parathyroidectomy/auto transplantation without cryopreservation can be applied as a safe and efficient surgical procedure.

Özet

Amaç: Bu çalışmada, kliniğimizde sekonder hiperparatiroidizm (HPT) olgularına uygulanan subtotal paratiroidektomi ve kriyoprezervasyonsuz total paratiroidektomi ve ototransplantasyon cerrahi yöntemlerinin erken ve geç dönem sonuçları ve etkinliklerinin karşılaştırılması amaçlanmıştır.Gereç ve Yöntem: Çalışmaya paratiroidektomi yapılan 68 sekonder HPT hastası dahil edildi ve hastalar retrospektif olarak değerlendirildi. Subtotal paratiroidektomi yapılan hastalar grup 1 (n=47) olarak, total paratiroidektomi ve ototransplantasyon yapılan hastalar grup 2 (n=21) olarak sınıflandırıldı. Hastaların demografik ve klinik özellikleri değerlendirildi.Bulgular: Ameliyatta, grup 1’de 8 hastaya (%14.9), grup 2’de 17 hastaya (%76.2) eş zamanlı timektomi yapıldı. Grup 1’de görülen persistan hiperparatiroidi (HPT) oranı %14.9 (n=7) iken, grup 2’de %4.8 (n=1) idi. Rekürren HPT grup 2’de görülmezken, grup 1’de %10.6 oranında (n=5) görüldü. Tüm hastalar değerlendirildiğinde, persistan veya rekürren HPT gelişen hastaların %69.2’sinde (n=9) neden, ektopik veya süpernumara bez varlığıydı.Sonuç: Son dönem böbrek yetmezlikli sekonder HPT tanılı hastalara, bilateral servikal timektominin eklendiği, kriyoprezervasyonsuz total paratiroidektomi ve ototransplantasyon tekniği, güvenli ve etkili bir cerrahi seçenek olarak uygulanabilir.

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Cite This Article

AVCI, T., KARAKAYALI, F. Y., YABANOĞLU, H., MORAY, G. (2018). Long term results of total parathyroidectomy/autotransplantation without cryopreservation in secondary hyperparathyroidism. Cukurova Medical Journal, Cilt: 43 Sayı: Ek 1, 129–138. https://ajindex.com/articles/56512

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