SavedAdd your journal

Journals / Journal of Neurological Sciences (Turkish) / 2014 / Cilt: 31 - Sayı: 1

Alzheimer Ve Lewy Cisimcikli Demans Hastalarında Uyku Bozuklukları

Sleep Disturbances in Patients With Alzheimer Disease and Dementia With Lewy Bodies

Barış BAKLAN
G. Görsev YENER
Derya Durusu SAVAŞ EMEK
Pages
144–154
Publication Date
2022-10-19
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Poor sleep quality and EDSwere greater in AD and DLB patients compared with controls.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: We compared subjective sleep quality, sleep disturbances and excessive daytimesleepiness (EDS) in non-demented elderly, patients with Alzheimer disease (AD) anddementia with Lewy bodies (DLB).
📊
Key Findings & Data:We investigated whether sleep dysfunction and EDS areassociated with the severity of dementia.Methods: The sleep profiles of 85 non-demented elderly, 84 patients with AD and 31 withDLB were assessed using two questionnaires, Pittsburgh Sleep Quality Index (PSQI) andEpworth Sleepiness Scale (ESS).
💡
Conclusion & Impact:Poor sleep quality and EDSwere greater in AD and DLB patients compared with controls.
🔬Design:Survey & Empirical Study
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: We compared subjective sleep quality, sleep disturbances and excessive daytimesleepiness (EDS) in non-demented elderly, patients with Alzheimer disease (AD) anddementia with Lewy bodies (DLB). We investigated whether sleep dysfunction and EDS areassociated with the severity of dementia.Methods: The sleep profiles of 85 non-demented elderly, 84 patients with AD and 31 withDLB were assessed using two questionnaires, Pittsburgh Sleep Quality Index (PSQI) andEpworth Sleepiness Scale (ESS). In order to evaluate the severity of dementia in patients withAD and DLB and to determine the non-demented elderly, Mini Mental State Examination(MMSE) and Clinical Dementia Rating Scale (CDR) were used.Results: AD and DLB patients had worse sleep quality and more sleep disturbances whencompared to non-demented elderly. EDS was also more frequent in AD and DLB patientsthan in non-demented elderly. There was no significant difference between AD and DLBpatients in terms of sleep quality or EDS. Having bad dreams -single item on PSQI- was morefrequent in DLB patients when compared with AD and non-demented elderly. Sleepdysfunction and EDS were not associated with the severity of dementia.Conclusion: Both patient groups had extensive sleep problems. Poor sleep quality and EDSwere greater in AD and DLB patients compared with controls.

Özet

Amaç: Alzheimer hastaları, Lewy Cisimli Demans (LCD) hastaları ve sağlıklı kontrolleröznel uyku kalitesi, uyku bozuklukları ve aşırı gündüz uykululuğu açısındankarşılaştırılmıştır. Uyku bozuklukları ve aşırı gündüz uykululuğunun demans şiddetinebağımlı olup olmadığı araştırılmıştır.Yöntem: 85 sağlıklı kontrol, 84 Alzheimer hastası ve 31 LCD hastasının uyku profilleriPittsburgh Uyku Kalitesi İndeksi (PUKİ) ve Epworth Uykululuk Ölçeği (EUÖ) kullanılarakdeğerlendirilmiştir. Mini Mental Durum Testi ve Klinik Demans Evrelendirme Ölçeği,Alzheimer ve LCD hastalarının demans şiddetini belirlemek ve sağlıklı kontrollerin demansolasılığını dışlamak için kullanılmıştır.Bulgular: Alzheimer ve LCD hastaları, sağlıklı kontrollerle karşılaştırıldığında daha kötüuyku kalitesi ve daha fazla uyku bozukluğu bildirmiştir. Aşırı gündüz uykululuğu da sağlıklıkontrollerle karşılaştırıldığında Alzheimer ve LCD hastalarında daha sık bildirilmiştir.Alzheimer ve LCD hastaları arasında uyku kalitesi ve aşırı gündüz uykululuğu açısındanistatistiksel olarak anlamlı fark bulunmamıştır. PUKİ'de tek bir item olan, Kötü rüyalargörme' LCD hastalarında Alzheimer hastaları ve sağlıklı kontrollerle karşılaştırıldığında dahasık bulunmuştur. Uyku bozuklukları ve aşırı gündüz uykululuğu ile hastaların demans şiddetiarasında istatistiksel olarak fark bulunmamıştır.Sonuç: İki hasta grubu da belirgin düzeyde uyku bozukluğu bildirmiştir. Kötü uyku kalitesive aşırı gündüz uykululuğu sağlıklı kontrollerle karşılaştırıldığında Alzheimer ve LCDhastalarında daha yaygındır.

🔖

Cite This Article

BAKLAN, B., YENER, G. G., EMEK, D. D. S. (2022). Alzheimer Ve Lewy Cisimcikli Demans Hastalarında Uyku Bozuklukları. Journal of Neurological Sciences (Turkish), Cilt: 31 - Sayı: 1, 144–154. https://ajindex.com/articles/564997

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (14)

  1. Ağargün MY, Çilli AS, Kara H, Bilici M et al. Ep worth Uykululuk Ölçeğinin Geçerliği ve Güvenirliği. Turk Psikiyatri Derg. 1999; 10(4): 261-267
  2. Ancoli-Israel S, Poceta JS, Step nowsky C, Martin J, Gehrman P. Identif ication and treatment of sleep p roblems in the elderly. Sleep Med Rev. 1997; 1(1): 3-17
  3. Beaulieu-Bonneau S, Hudon C. Sleep disturbances in older adults with mild cognitive imp airment. Int Psychogeriatr. 2009; 21(4): 654-666
  4. Beck AT, Ward CH, Mendelson M, Mock J, Erbaugh J. An inventory f or measuring dep ression. Arch Gen Psychiatry 1961; 4: 53- 63
  5. Bhatt MH, Podder N, Chokroverty S. Sleep and neurode-generative disorders. Semin Neurol. 2005; 25: 39–51
  6. Boddy F, Rowan EN, Lett D, O'Brien JT, McKeith IG, Burn DJ. Subj ectively rep orted sleep quality and excessive daytime somnolence in Parkinson's disease with and without dementia, dementia with Lewy bodies and Alzheimer's disease. Int J Geriatr Psychiatry. 2007; 22(6): 529-535
  7. Boeve BF, Silber MH, Ferman TJ. REM sleep behavior disorder in Parkinson's disease and dementia with Lewy bodies. J Geriatr Psychiatry Neurol. 2004; 17: 146–157
  8. Buysse DJ, Reynolds CF 3rd, Monk TH, Bermann SR, Kupf er DJ. The Pittsburgh sleep quality index: A new instrument f or psychiatric p ractice and research. Psychiatry Res. 1989; 28: 193-213
  9. Dauvilliers Y. Insomnia in p atients with neurodegenerative conditions. Sleep Med. 2007; 4: 27–34
  10. Ferman TJ, Boeve BF, Smith GE, Silber MH, Lucas JA, Graff -Radf ord NR, Dickson D W, Parisi JE, Petersen RC, Ivnik RJ. Dementia with Lewy bodies may p resent as dementia and REM sleep behavior disorder without p arkinsonism or hallucinations. J Int Neuropsychol Soc. 2002; 8(7): 907-914
  11. Fetveit A, Bj orvatn B. Sleep duration during the hour day is associated with the severity of dementia in nursing home p atients. Int J Geriatr Psychiatry. 2006; 21: 945-950
  12. Foley D, Monj an A, Masaki K, Ross W, Havlik R, White L, Launer L. Daytime sleep iness is associated with 3-year incident dementia and cognitive decline in older Jap anese-American men. J Am Geriatr Soc. 2001; 49(12): 1628- 1632
  13. Foley D, Ancoli-Israel S, Britz P, Walsh J. Sleep disturbances and chronic disease in older adults: results of the 2003 National Sleep Foundation Sleep in America Survey. J Psychosom Res 2004; 56: 497-502
  14. Folstein MF, Folstein S, McHugh PR. 'Mini- mental State': A p ractical method f or grading the cognitive state of p atient f or the clinic