Journals / Journal of Neurological Sciences (Turkish) / 2016 / Cilt: 33 - Sayı: 2

Neuroimaging Evaluation of Non-Aneurismatic "Top of the Basilar" Syndrome

Non-Anevrizmatik Baziller Tepe Sendromunda Nöroradyolojik Değerlendirme

Pages
286–295
Publication Date
2022-10-19
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Familiarity with the vascular anatomy, supplying territories, and infarction patterns of the ischemic lesions is crucial.

📌 3 Key Takeaways

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Objective & Hypothesis:Purpose: We aim to evaluate the clinical and imaging features of "Top of the basilar" syndrome (TOB-S).
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Key Findings & Data:Results: Thirty patients (14 males and 16 females) with a mean age of 61 years (range: 32-78 years) were diagnosed as TOB-S based on the neuroimaging and clinical findings.
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Conclusion & Impact:Familiarity with the vascular anatomy, supplying territories, and infarction patterns of the ischemic lesions is crucial.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Purpose: We aim to evaluate the clinical and imaging features of "Top of the basilar" syndrome (TOB-S). Method: We retrospectively evaluated the clinical and imaging features of thirty consecutive TOB-S patients. We analyzed the ischemic parenchymal lesions and vascular disturbances with anatomic correlation by using magnetic resonance imaging (MRI), diffusion-weighted MRI (DWI), computed tomography angiography (CTA), magnetic resonance angiography (MRA), and digital subtraction angiography (DSA). Results: Thirty patients (14 males and 16 females) with a mean age of 61 years (range: 32-78 years) were diagnosed as TOB-S based on the neuroimaging and clinical findings. Large artery atherosclerosis (LAA) was the common etiology (63.3%), including the subgroups of in situ steno/occlusive, artery to artery embolus (AA), arterial branch (AB) occlusion, and AA+AB combination. The other etiologies were cardioembolism (CE) (16.6%), arterial dissection (AD) (10.0%), vasculitis (6.6%), and undetermined (3.3%). The patients represented 'superficial', 'deep' and 'superficial plus deep' infarcts with segmental, territorial or scattered patterns. The most clinical manifestations were motor deficits, alteration of consciousness, visual/oculomotor disturbance, cerebellar dysfunction, behavioral disorder and speech disorder. Conclusion: The accurate evaluation of imaging findings in TOB-S is essential for diagnosis and appropriate management. Familiarity with the vascular anatomy, supplying territories, and infarction patterns of the ischemic lesions is crucial.

Özet

Amaç: Non-anevrizmatik ''Baziller Tepe'' (BTS) sendromunda nöroradyolojik bulguların değerlendirilmesi. Metod: BTS tanısı alan otuz hastanın klinik ve görüntüleme bulguları retrospektif olarak incelendi. İskemik parenkimal ve vasküler lezyonlar anatomik korelasyonlarıyla birlikte manyetik rezonans görüntüleme (MRG), diffüzyon ağırlıklı görüntüleme (DAG), bilgisayarlı tomografik anjiografi (BTA) ve dijital subtraksiyon anjiografi (DSA) metodlarıyla incelendi. Bulgular: Otuz hastaya (14 erkek-16 kadın) ortalama yaş 61 (32-78 arası) klinik ve nöroradyolojik görüntüleme ile BTS tanısı kondu. Büyük arter aterosklerozu (BAA) en yaygın etyoloji olup (%66.6) in-situ stenookluziv, arter-arter (AA) embolisi, arteryel dal (AD) oklüzyonu ve AA+AD kombinasyonları olarak alt gruplara ayrılarak incelendi. Takip eden diğer etyolojiler kardiyoembolizm (KE) (%16.6), arteryel disseksiyon (%10.0), vaskülit (%6.6) ve belirlenemeyen (%3.3) idi. Hastalarda iskemi ''süperfisyal'', ''' derin'' ve '''süperfisyal+derin'' lokalizasyonlarda olup segmental, teritoryal ve multipl dağınık küçük infarkt paternleri şeklinde görüldü. En sık görülen klinik bulgular, motor bozukluklar, bilinç değişiklikleri, vizual/okülomotor bozukluklar, serebellar disfonksiyon ile davranış ve konuşma bozukluklarıydı. Sonuç: BTS tanı ve tedavisinde etkin nöroradyolojik görüntüleme önemlidir. Bu bölgedeki vasküler anatomi ve besleme alanları ile iskemik infarkt paternlerinin iyi bilinmesi hayati önem taşır.

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Cite This Article

HEREK, D., AGLADIOGLU, K., TEKE, E., KIROĞLU, Y., CITISLI, V., ONUR, S. (2022). Neuroimaging Evaluation of Non-Aneurismatic "Top of the Basilar" Syndrome. Journal of Neurological Sciences (Turkish), Cilt: 33 - Sayı: 2, 286–295. https://ajindex.com/articles/564895

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