Journals / Journal of Neurological Sciences (Turkish) / 2016 / Cilt: 33 - Sayı: 2

Entorhinal Cortex: Where We Stand Now?

Entorinal Korteks: Şimdi Nerede Duruyoruz?

Pages
401–413
Publication Date
2022-10-19
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The aim of this review is to summarize the anatomy, histology and connections of the EC, present the results of recent researches and point out new challenges on the hippocampal formation and EC.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Hippocampus and the medial temporal lobe are involved in the formation of new, long term, declarative memories and navigation.
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Key Findings & Data:Navigation in animals builds on a distributed, modularly functioning and organized large brain network.
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Conclusion & Impact:The aim of this review is to summarize the anatomy, histology and connections of the EC, present the results of recent researches and point out new challenges on the hippocampal formation and EC.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Hippocampus and the medial temporal lobe are involved in the formation of new, long term, declarative memories and navigation. Navigation in animals builds on a distributed, modularly functioning and organized large brain network. The exact computations and neural connections that underlie the hippocampal processing are still not well understood. The entorhinal cortex (EC) is the major source of input for the hippocampus. It has two distinct and functional processing streams into the hippocampus. Hippocampus receives its primary cortical input from the medial and lateral EC. On the other hand, EC receives input from other cortical areas such as perirhinal cortex and parahippocampal gyrus. So, EC is a small but important interface between the hippocampus and neocortex. The aim of this review is to summarize the anatomy, histology and connections of the EC, present the results of recent researches and point out new challenges on the hippocampal formation and EC.

Özet

Hipokampus ve medial temporal lob yeni, uzun süreli ve bildirimsel bellek ve yön bulma konusunda önemli fonksiyonlara sahiptir. Hayvanlarda yön bulma yaygın ve modüler şekilde organize olmuş ve fonksiyon gören yaygın beyin şebekesi sayesinde olmaktadır. Hipokampal fonksiyonları oluşturan hassas ölçümler ve nöronal yollar halen tam olarak bilinmemektedir. Entorinal korteks (EK) hipokampusa gelen bilginin ana kaynağını oluşturmaktadır. Buradan hipokampusa giden 2 tane ana fonksiyonel akım yolu vardır. Hipokampus primer kortikal bilgi girişini medial ve lateral EK'den sağlamaktadır. Diğer yandan, EK diğer beyin kortikal alanlarından (peririnal korteks ve parahipokampal girus) girdi almaktadır. Yani EK hipokampus ile neokorteks arasında küçük ama önemli bir arayüzdür. Bu derlemenin amacı entorinal korteksin anatomi, histoloji ve bağlantılarını özetlemek, bu konuda son yıllarda yapılmış çalışmaların sonuçlarını sunmak ve hipokampal oluşum ile entorinal korteksdeki yeni gelişmeleri vurgulamaktır.

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Cite This Article

İZCİ, Y., ERBAŞ, C., EZGÜ, M. C. (2022). Entorhinal Cortex: Where We Stand Now?. Journal of Neurological Sciences (Turkish), Cilt: 33 - Sayı: 2, 401–413. https://ajindex.com/articles/564892

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