Journals / Journal of Clinical and Experimental Investigations / 2014 / Cilt: 5 - Sayı: 2

Biomarkers in the diagnosis of acute appendicitis

Akut apandisit tanısında biyobelirteçler

Pages
250–255
Publication Date
2022-10-18
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

When taken 11,6 x103 for leukocyte, 8.5 x103 for neutrophil, 3.9 for NLO, while specificity of total was 78.8%, sensitive 73.6% was found.Conclusion: Together evaluation of neutrophils, lymphocytes and NLR which are routinely used hemogram parameters in association of physical examination is seem to be more appropriate.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Patients who is presented to ED with the complaint of abdominal pain account an important number in the ED practice.
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Key Findings & Data:Methods: Data of 520 patients who were operated with the presumed diagnosis of appendicitis in our hospital between 01/01/2012 and 31/12/2013 were retrospectively screened.
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Conclusion & Impact:When taken 11,6 x103 for leukocyte, 8.5 x103 for neutrophil, 3.9 for NLO, while specificity of total was 78.8%, sensitive 73.6% was found.Conclusion: Together evaluation of neutrophils, lymphocytes and NLR which are routinely used hemogram parameters in association of physical examination is seem to be more appropriate.
🔬Design:Research Article
📍Scope:2012 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: Patients who is presented to ED with the complaint of abdominal pain account an important number in the ED practice. Availability of rapid and inexpensive tests is crucial in the differential diagnosis of these patients. Hemogram parameters is one of them. In this study, we investigated the biomarkers in hemogram parameters of the patients diagnosed with acute appendicitis. Methods: Data of 520 patients who were operated with the presumed diagnosis of appendicitis in our hospital between 01/01/2012 and 31/12/2013 were retrospectively screened. Of the 410 patients whom data were fully reached, leukocyte, neutrophil and lymphocyte counts, neutrophil / lymphocyte ratio (NLR), pathology results and at the admission time and superficial tissue ultrasonography (USG) reports if further investigation has been made were recorded.Results: According to the pathological diagnosis of 334 patients (81.5%), while appendicitis 76 patients (18.5%) was not appendicitis. When taken 11,6 x103 for leukocyte, 8.5 x103 for neutrophil, 3.9 for NLO, while specificity of total was 78.8%, sensitive 73.6% was found.Conclusion: Together evaluation of neutrophils, lymphocytes and NLR which are routinely used hemogram parameters in association of physical examination is seem to be more appropriate.

Özet

Amaç: Akut apandisit acil servis pratiğinde halen önemli bir yer tutmaktadır. Bu hastaların ayırıcı tanısında kullanılan testlerin hızlı, kolay ulaşılabilir ve ucuz olması gerekmektedir. Hemogram parametreleri bu testlerin başında gelmektedir. Bu çalışmada akut apandisit tanısı için hemogram parametelerinin etkinliği incelenmiştir. Yöntemler: Hastanemizde Ocak 2012 ile Aralık 2013 yılları arasında apandisit ön tanısıyla opere edilen 520 hastanın verileri retrospektif olarak incelendi. Verilerine tam olarak ulaşılan 410 hastanın hastaneye başvurduğunda alınan ilk tam kan sayımındaki lökosit, nötrofil, lenfosit sayımları, nötrofil/lenfosit oranları (NLO), patoloji sonuçları ve ileri tetkik olarak yapılmışsa yüzeyel doku ultrasonografi (USG) raporları kaydedildi.Bulgular: Hastaların patolojik tanılarına göre 334'ü (%81,5) apandisit iken 76'sı (%18,5) apandisit değildi. Lökosit için 11,6x103, nötrofil için 8,5x103, NLO için 3,9 alındığında toplamlarının sensitivitesi %73,6 iken spesifitesi %78,8 olarak bulundu.Sonuç: Akut apandisit tanısında fizik muayene bulguları eşliğinde rutin kullanılan hemogram parametrelerinden olan lökosit, nötrofil ve NLO'nun birlikte değerlendirilmesi daha kullanışlı olabilir.

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Cite This Article

DUMAN, A., TÜRKDOĞAN, K. A., KAPÇI, M., GÜLEN, B., AVCİL, M., YILMAZ, Y., UĞURLU, Y., ÖKKEŞ, T. (2022). Biomarkers in the diagnosis of acute appendicitis. Journal of Clinical and Experimental Investigations, Cilt: 5 - Sayı: 2, 250–255. https://ajindex.com/articles/561750

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