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Journals / Journal of Clinical and Analytical Medicine / 2014 / Cilt: 5 - Sayı: 3

Reye-like Sendromu Olan Çocuklarda Klinik Prezentasyon, Tedavi ve Prognoz

Clinical Presentation, Treatment and Prognosis in Children with Reye-like Syndrome

Şükrü ARSLAN
Cengizhan KILIÇASLAN
Dursun ODABAŞ
Hüseyin BİLGİN
Pages
191–194
Publication Date
2022-10-18
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In conclusion, Reye like syndrome occurs only rarelybut should be a part of the differential diagnosis of any encephalopathy ofunknown origin and above all if there is a history of ingestion of drugs, previous viral infection and vomiting.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:We performed a retrospective study to explore the mortality rates and prognosis of the Reye like syndrome in patients treated at Konya Research andEducation Hospital.
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Key Findings & Data:Twenty two children with ages between 5 months and 7years old were included in this study.
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Conclusion & Impact:In conclusion, Reye like syndrome occurs only rarelybut should be a part of the differential diagnosis of any encephalopathy ofunknown origin and above all if there is a history of ingestion of drugs, previous viral infection and vomiting.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

We performed a retrospective study to explore the mortality rates and prognosis of the Reye like syndrome in patients treated at Konya Research andEducation Hospital. Twenty two children with ages between 5 months and 7years old were included in this study. All patients were treated with intensivesupportive methods to manage body fluid, blood circulation, respiration, bodytemperature, and intracranial pressure. The main presenting features werehistory of fever (72.7%), profuse vomiting (63.6%), abnormal behavior andagitation (77.2%), and sudden onset of unconsciousness (100%). The etiologies of patients included viral illness, gastroenteritis, metabolic disorders, intoxication and hypoxia due to foreign body aspiration. No neurological deficitwas seen in the children who survived the disease. In our patients the mortality rate was 31.8%. In conclusion, Reye like syndrome occurs only rarelybut should be a part of the differential diagnosis of any encephalopathy ofunknown origin and above all if there is a history of ingestion of drugs, previous viral infection and vomiting. Our treatment protocol is safe and effectivein children with Reye like syndrome.

Özet

Konya Eğitim ve Araştırma Hastanesinde tedavi edilen Reye like Sendromuolan hastaların mortalite oranlarını ve prognozlarını araştırmak için retrospektif bir çalışma yaptık. Yaşları 5 ay ile 7 yaş arasında olan 22 çocuk çalışmaya dahil edildi. Tüm hastalar vücut sıvısı, kan dolaşımı, solunum, vücut ısısı ve intrakraniyel basıncını idare etmek için destekleyici yöntemlerle tedaviedildi. Temel prezentasyon özellikleri ateş (% 72,7), kusma (% 63,6), anormaldavranış ve ajitasyon (% 72,7) ve ani başlayan bilinç bulanıklığıdır (%100).Çalışmaya alınan hastalarda etiyoloji; viral hastalık, gastroenterit, metabolikhastalık, intoksikasyon ve yabancı cisim aspirasyonuna bağlı hipoksi. Hastalığı atlatan çocuklarda nörolojik defisit izlenmemiştir. Hastalarımızda mortalite oranı % 31,8 idi. Sonuç olarak, Reye like sendromu nadiren görülür; fakatnedeni bilinmeyen ensefalopatilerde, özellikle eğer viral enfeksiyon, kusma veilaç alım öyküsü varsa ayırıcı tanının bir parçası olmalıdır. Tedavi protokolümüz Reye like sendromu olan çocuklarda güvenilir ve etkilidir.

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Cite This Article

ARSLAN, Ş., KILIÇASLAN, C., ODABAŞ, D., BİLGİN, H. (2022). Reye-like Sendromu Olan Çocuklarda Klinik Prezentasyon, Tedavi ve Prognoz. Journal of Clinical and Analytical Medicine, Cilt: 5 - Sayı: 3, 191–194. https://ajindex.com/articles/561530

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