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Journals / Journal of Clinical and Analytical Medicine / 2014 / Cilt: 5 - Sayı: 1

Kemik metastazı yapmış prostatın primer nöroendokrin tümörü

Primary neuroendocrine tumor of the prostate with bone metastasis

İlke Onur KAZAZ
Doğan Sabri TOK
Abdullah SİVRİKAYA
Ersagun KARAGÜZEL
Sevdegül MUNGAN
Pages
67–68
Publication Date
2022-10-18
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The pathological assessment of the biopsy revealed metastasis of a poorly-differen- tiated neuroendocrine carcinoma confirming the bone metastasis of the primary neuroendocrine tumor of the prostate.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Primary neuroendocrine tumors of the prostate are very rare and their biologic behaviour is not yet well described.
📊
Key Findings & Data:A 50-year-old man presented with a 6 months history of frequent urination, difficulty in urination and failure to empty the bladder.
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Conclusion & Impact:The pathological assessment of the biopsy revealed metastasis of a poorly-differen- tiated neuroendocrine carcinoma confirming the bone metastasis of the primary neuroendocrine tumor of the prostate.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Primary neuroendocrine tumors of the prostate are very rare and their biologic behaviour is not yet well described. A case of primary, prostatic, neuroendocrine tumor with bone metastasis is described. A 50-year-old man presented with a 6 months history of frequent urination, difficulty in urination and failure to empty the bladder. Transurethral prostate resection was performed and the pathological examination of the prostate tissue revealed a poorly-differentiated neuroen-docrine carcinoma. Meanwhile, cervical magnetic resonance imaging that was planned due to the presence of neck pain revealed a mass lesion in the right paravertebral soft tissue and a pathological compression fracture of the C6 vertebral body. The patient underwent an operation in which C6 corpectomy, placement of homogenous bone graft and obtaining a biopsy specimen were performed. The pathological assessment of the biopsy revealed metastasis of a poorly-differen- tiated neuroendocrine carcinoma confirming the bone metastasis of the primary neuroendocrine tumor of the prostate.

Özet

Prostatın primer nöroendokrin tümörleri çok nadir ve biyolojik davranışları henüzçok iyi açıklanamamış tümörlerdir. Bu makalede primer prostat nöroendokrin tümörü ve kemik metastazı olan bir olgu sunulmaktadır. Altı aydır sık idrara çıkma, işemede zorluk ve mesanesini tam boşaltamama şikayetleri mevcut olan 50 yaşında erkek hastaya, transüretral prostat rezeksiyonu yapıldı. Patoloji sonucu az diferansiye nöroendokrin karsinom olarak rapor edildi. Hastanın boyun ağrısı nedeniyle yapılan servikal manyetik rezonans tetkikinde sağ paravertebral yumuşak dokuda bir kitle ve C6 vertebrada patolojik kompresyon kırığı tespit edildi. Hastaya kitlenin eksizyonunu takiben, C6 korpektomi ve homojen kemik grefti konulması operasyonu yapıldı. Paravertebral kitlenin patolojik incelenmesi sonucu az diferansiye nöroendokrin tümor metastazı olduğu tespit edildi. Lezyonun prostatın primer nöroendokrin tümörünün kemik metastazı olduğu konfirme edilmiş oldu.

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Cite This Article

KAZAZ, İ. O., TOK, D. S., SİVRİKAYA, A., KARAGÜZEL, E., MUNGAN, S. (2022). Kemik metastazı yapmış prostatın primer nöroendokrin tümörü. Journal of Clinical and Analytical Medicine, Cilt: 5 - Sayı: 1, 67–68. https://ajindex.com/articles/561519

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