Journals / Journal of Clinical and Analytical Medicine / 2012 / Cilt: 3 - Sayı: 4

Cep telefonlarının yaydığı elektromanyetik alanın (EMA) sıçan modelinde femur kırık iyileşmesi üzerine etkisi

Healingthe effect of GSM mobile phone electromagnetic field on femur fracture healing in a rat model

Pages
388–392
Publication Date
2022-10-18
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Fracture healing, as assessed biomechanically, was significantly better in Group EM compared to controls in those sacrificed at 2nd week post-procedure (p

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: Biological effects of electromagnetic field (EMF) and their consequences on human health have been the subject of much interest and research in recent years.
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Key Findings & Data:The aim of this study was to investigate the effects of 900 MHz EMF on femur fracture healing in a rat model.
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Conclusion & Impact:Fracture healing, as assessed biomechanically, was significantly better in Group EM compared to controls in those sacrificed at 2nd week post-procedure (p
🔬Design:Modeling & Simulation
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Aim: Biological effects of electromagnetic field (EMF) and their consequences on human health have been the subject of much interest and research in recent years. The aim of this study was to investigate the effects of 900 MHz EMF on femur fracture healing in a rat model. Material and Method: After sixty male Sprague-Dawley rats were exposed to a closed right femur fracture under anesthesia, the reduction and fixation were done with a 21 g needle. Then, 900 MHz radiation (2 W peak output power and 1.04 mW/cm2 power density) was applied to EM group for one hour/day for seven days. The healing was assessed using radiological (Lane and Sandhu classification), histological (Huo scale for callus evaluation), and biomechanical (3-point bending) measures at 2nd, 4th and 6th weeks after fracture. Results: Fracture healing, as assessed radiologically and histopathologically, in Group EM and control animals was similar at 2nd, 4th and 6th weeks. Fracture healing, as assessed biomechanically, was significantly better in Group EM compared to controls in those sacrificed at 2nd week post-procedure (p

Özet

Amaç: Son zamanlarda cep telefonlarının elektromanyetik alanın biyolojik et-kileri ve insan sağlığına etkiler araştırmacıların çok dikkatini çekmiştir. Bu ça-lışmada amaç 900 MHz ile çalışan cep telefonlarının sıçan modellerinde fe-mur kırık iyileşmesi üzerine etkisini araştırmaktır. Gereç ve Yöntem: Altmış adet Sprague-Dawley sıçanda anestezi altında sağ femur kapalı kırığı oluş-turuldu. Hemen arkasından kapalı redüksiyon sonrası 21 G enjektör iğnesi ile tespit yapıldı. Bunlardan otuz adet sıçan EM grubuna alınarak 7 gün boyun-ca 1 saat/gün süresince 900 MHz radyasyon (2 W peak output power ve 1.04 mW/cm2 power density) uygulandı. Diğer otuz adet sıçan ise kontrol grubuna alınarak doğal iyileşme sürecine bırakıldı. Kırık iyileşmesi ikinci ,4. ve 6. hafta-larda radyolojik (Lane and Sandhu sınıflandırması), histolojik (Huo skalası) ve biyomekanik (3-point bending) olarak değerlendirildi. Bulgular: Histopatolojik ve radyolojik incelemede EM ve kontrol grubu arasında kırık iyileşmesi arasın-da fark izlenmedi. Biyomekanik incelemede 2. haftada EM grubunda kontrol grubundan istatistiksel olarak daha anlamlı bir hızlı iyileşme izlendi (p

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Cite This Article

ALTAY, M. A., ÖZBAĞ, D., GÖKTAŞ, U., ÜN, A., OKUMUŞ, M., KALENDER, A. M., ERTÜRK, C., GÜNER, S. (2022). Cep telefonlarının yaydığı elektromanyetik alanın (EMA) sıçan modelinde femur kırık iyileşmesi üzerine etkisi. Journal of Clinical and Analytical Medicine, Cilt: 3 - Sayı: 4, 388–392. https://ajindex.com/articles/561355

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References (15)

  1. Szentpali B. Human exposure to electromagnetic fields from mobile telephones. IEEE 1999;47:222-31
  2. Somosy Z. Radiation response of cell organelles. Micron 2000;31:165-81
  3. Fritze K, Sommer C, Schimtz B, Mies G, Hossmann KA, et al. Effect of global system for mobile communication (GSM) microwave exposure on blood-brain barrier permeability in rat. Acta Neuropathol 1997;94:465-70
  4. Jensh RP. Behavioral teratologic studies using microwave radiation: Is there an increased risk from exposure to cellular phones and microwave ovens? Reproduct Toxicol 1997; 11:601-11
  5. Li JR, Chou CK, McDougall JA, Dasgupta G, Wu HH, et al. TP53 Tumor suppressor protein in normal human fibroblasts does not respond to 837 MHz microwave exposure. Radiat Res 1999;151:710-6
  6. Dasdag S, Ketani MA, Akdag Z, Ersay AR, Sari I, et al. Whole-body microwave exposure emitted by cellular phones and testicular function of rats. Urol Res 1999;27:219-23
  7. Dasdag S, Akdag MZ, Ayyıldız O, Demirtas OC, Yayla M, Sert C. Do cellular phones alter blood parameters and birth weight of rats? Electro- and Magnetobiology 2000;19:107-13
  8. Sert C, Mustafa D, Düz MZ, Akşen F, Kaya A. The preventive effect on bone loss of 50-Hz, 1-mT electromagnetic field in ovariectomized rats. J Bone Miner Metab 2002; 20:345-49
  9. Stanosz S, Stanosz M, Wysocki K. The appreciation of bone growth factor in women with osteoporosis exposing on free transition magnetic field. Pol Merkur Lekarski 2004; 17:229-31
  10. Chang K, Chang WH. Pulsed electromagnetic fields prevent osteoporosis in an ovariectomized female rat model: a prostaglandin E2Y associated process. Bioelectromagnetics 2003; 24:189-98
  11. Zhang XY, Xue Y, Zhang Y. Effects of 0.4T rotating magnetic field exposure on density, strength, calcium and metabolism of rat thigh bones. Bioelectromagnetics 2006; 27:1-9
  12. Bonnarens F, Einhorn TA. Production of a standard closed fracture in laboratory animal bone. J Orthop Res 1984;2: 97-101
  13. Lane JM, Sandhu HS. Current approaches to experimental bone grafting. Orthop Clin North Amer 1987; 18:213-25
  14. Nakamura T, Kurokawa T, Orimo H. Increased mechanical strength of the vitamin D-replete rat femur by the treatment with a large dose of 24R,25(OH) 2D3. Bone 1989; 10: 117-23
  15. Huo MH, Troiano NW, Pelker RR, Gundberg CM, Friedlaender GE. The influence of ibuprofen on fracture repair: biomechanical, biochemical, histologic, and histomorphometric parameters in rats. J Orthop Res 1991; 9:383-90